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YRR1

YOR162C, PDR2

View at SGD ↗

Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Macisaac et. al
Fisher’s P-value4.90e-07
Information content16.45
Max PWM score14.39
Recommended cutoff13.12
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.001 0.211 0.263 0.001 0.053 0.053 0.001 0.945 0.001 0.001 0.001 0.315 
C | 0.001 0.105 0.053 0.158 0.053 0.001 0.105 0.001 0.945 0.736 0.997 0.001 
G | 0.053 0.001 0.001 0.001 0.893 0.001 0.001 0.001 0.001 0.262 0.001 0.631 
T | 0.945 0.683 0.683 0.840 0.001 0.945 0.893 0.053 0.053 0.001 0.001 0.053 
Position count matrix (PCM)
A |   0  21  26   0   5   5   0  94   0   0   0  31 
C |   0  10   5  15   5   0  10   0  94  73  99   0 
G |   5   0   0   0  89   0   0   0   0  26   0  63 
T |  94  68  68  84   0  94  89   5   5   0   0   5 
Position weight matrix (PWM)
A | -5.77 -0.42 -0.20 -5.77 -1.80 -1.80 -5.77  1.08 -5.77 -5.77 -5.77 -0.02 
C | -5.19 -0.54 -1.22 -0.13 -1.22 -5.19 -0.54 -5.19  1.66  1.41  1.71 -5.19 
G | -1.22 -5.19 -5.19 -5.19  1.60 -5.19 -5.19 -5.19 -5.19  0.38 -5.19  1.25 
T |  1.08  0.76  0.76  0.97 -5.77  1.08  1.03 -1.80 -1.80 -5.77 -5.77 -1.80 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 5

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

YRR1Badis et. al.P = 0.5975View matrix ↘
Sequence logo for YRR1
Fisher’s P-value0.5975
Information content9.638
Max PWM score10.26
Recommended cutoff5.17
Position frequency matrix (PFM)
A | 0.16 0.22 0.89 0.19 0.28 0.04 0.01 0.01 0.03 0.06 
C | 0.16 0.08 0.01 0.09 0.33 0.22 0.97 0.97 0.01 0.41 
G | 0.10 0.04 0.02 0.04 0.08 0.07 0.01 0.01 0.94 0.14 
T | 0.58 0.66 0.08 0.68 0.32 0.67 0.01 0.01 0.02 0.39 
Position count matrix (PCM)
A |  16  22  89  19  28   4   1   1   3   6 
C |  16   8   1   9  33  22  97  97   1  41 
G |  10   4   2   4   8   7   1   1  94  14 
T |  57  66   8  68  32  67   1   1   2  39 
Position weight matrix (PWM)
A | -0.69 -0.37  1.02 -0.52 -0.13 -2.08 -3.47 -3.47 -2.37 -1.67 
C | -0.12 -0.81 -2.89 -0.69  0.61  0.20  1.68  1.68 -2.89  0.82 
G | -0.59 -1.50 -2.20 -1.50 -0.81 -0.94 -2.89 -2.89  1.65 -0.25 
T |  0.59  0.72 -1.39  0.75  0.00  0.74 -3.47 -3.47 -2.77  0.20 
YRR1Foat et. al.P = 8.48e-06View matrix ↘
Sequence logo for YRR1
Fisher’s P-value8.48e-06
Information content12.85
Max PWM score14.81
Recommended cutoff10.64
Position frequency matrix (PFM)
A | 0.13 0.08 0.14 0.92 0.03 0.95 0.47 0.43 0.02 0.97 0.01 0.43 0.13 0.66 0.04 
C | 0.14 0.11 0.63 0.01 0.36 0.03 0.13 0.02 0.71 0.01 0.08 0.56 0.08 0.01 0.04 
G | 0.01 0.01 0.15 0.06 0.03 0.01 0.02 0.01 0.01 0.01 0.58 0.01 0.55 0.18 0.77 
T | 0.72 0.80 0.07 0.01 0.58 0.01 0.38 0.55 0.27 0.01 0.34 0.01 0.24 0.14 0.15 
Position count matrix (PCM)
A |  13   8  14  92   3  95  47  43   2  97   1  43  13  66   4 
C |  14  11  63   1  36   3  13   2  71   1   8  56   8   1   4 
G |   1   1  15   6   3   1   2   1   1   1  57   1  55  18  77 
T |  72  80   7   1  57   1  38  55  27   1  34   1  24  14  15 
Position weight matrix (PWM)
A | -0.90 -1.39 -0.83  1.06 -2.37  1.09  0.38  0.30 -2.77  1.11 -3.47  0.30 -0.90  0.72 -2.08 
C | -0.25 -0.49  1.25 -2.89  0.69 -1.79 -0.33 -2.20  1.37 -2.89 -0.81  1.13 -0.81 -2.89 -1.50 
G | -2.89 -2.89 -0.18 -1.10 -1.79 -2.89 -2.20 -2.89 -2.89 -2.89  1.17 -2.89  1.12  0.00  1.45 
T |  0.81  0.92 -1.52 -3.47  0.59 -3.47  0.17  0.54 -0.17 -3.47  0.06 -3.47 -0.29 -0.83 -0.76 
YRR1Morozov et. al.P = 0.2133View matrix ↘
Sequence logo for YRR1
Fisher’s P-value0.2133
Information content5.755
Max PWM score7.18
Recommended cutoff3.62
Position frequency matrix (PFM)
A | 0.066 0.414 0.282 0.050 0.140 0.015 
C | 0.846 0.106 0.095 0.845 0.084 0.056 
G | 0.054 0.177 0.487 0.021 0.672 0.805 
T | 0.034 0.303 0.136 0.083 0.104 0.123 
Position count matrix (PCM)
A |   6  41  28   5  14   1 
C |  84  10   9  84   8   5 
G |   5  17  48   2  67  80 
T |   3  30  13   8  10  12 
Position weight matrix (PWM)
A | -1.58  0.26 -0.13 -1.86 -0.83 -3.06 
C |  1.55 -0.53 -0.64  1.55 -0.76 -1.17 
G | -1.20 -0.02  1.00 -2.15  1.32  1.50 
T | -2.24 -0.05 -0.86 -1.35 -1.12 -0.96 
YRR1Zhu et. al.P = 0.9775View matrix ↘
Sequence logo for YRR1
Fisher’s P-value0.9775
Information content13.55
Max PWM score12.17
Recommended cutoff6.47
Position frequency matrix (PFM)
A | 0.34 0.01 0.01 0.01 0.92 0.73 0.88 0.01 0.83 0.87 
C | 0.05 0.96 0.01 0.02 0.01 0.03 0.01 0.01 0.01 0.06 
G | 0.60 0.01 0.97 0.96 0.05 0.12 0.01 0.01 0.01 0.05 
T | 0.01 0.02 0.01 0.01 0.01 0.12 0.10 0.97 0.15 0.02 
Position count matrix (PCM)
A |  34   1   1   1  92  73  88   1  83  87 
C |   5  96   1   2   1   3   1   1   1   6 
G |  60   1  97  96   5  12   1   1   1   5 
T |   1   2   1   1   1  12  10  97  15   2 
Position weight matrix (PWM)
A |  0.06 -3.47 -3.47 -3.47  1.06  0.82  1.01 -3.47  0.95  1.00 
C | -1.28  1.67 -2.89 -2.20 -2.89 -1.79 -2.89 -2.89 -2.89 -1.10 
G |  1.20 -2.89  1.68  1.67 -1.28 -0.41 -2.89 -2.89 -2.89 -1.28 
T | -3.47 -2.77 -3.47 -3.47 -3.47 -0.98 -1.16  1.11 -0.76 -2.77 
YRR1Zhao and StormoP = 0.6951View matrix ↘
Sequence logo for YRR1
Fisher’s P-value0.6951
Information content5.884
Max PWM score6.65
Recommended cutoff4.6
Position frequency matrix (PFM)
A | 0.650 0.266 0.261 0.080 0.030 0.001 0.146 
C | 0.068 0.142 0.261 0.242 0.817 0.997 0.046 
G | 0.106 0.103 0.160 0.135 0.152 0.001 0.725 
T | 0.175 0.490 0.319 0.543 0.001 0.001 0.083 
Position count matrix (PCM)
A |  65  26  26   8   3   0  14 
C |   6  14  26  24  81  99   4 
G |  10  10  16  13  15   0  72 
T |  17  49  31  54   0   0   8 
Position weight matrix (PWM)
A |  0.71 -0.18 -0.20 -1.39 -2.37 -5.77 -0.78 
C | -0.97 -0.24  0.37  0.30  1.51  1.71 -1.36 
G | -0.53 -0.56 -0.12 -0.29 -0.17 -5.19  1.39 
T | -0.60  0.43 -0.00  0.53 -5.77 -5.77 -1.35 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 157 genes

YAL062W, YAR007C, YAR008W, YBL068W, YBL070C, YBL089W, YBL108W, YBR076W, YBR109C, YBR110W, YBR167C, YBR168W, YBR185C, YBR186W, YBR204C, YBR205W, YBR206W, YCL002C, YCL006C, YCL007C, YCL008C, YCL009C, YCL010C, YCR002C, YCR004C, YCR005C, YCR006C, YCR008W, YCR012W, YCR030C, YCR096C, YDL091C, YDL092W, YDL094C, YDL104C, YDL114W, YDL115C, YDR020C, YDR021W, YDR030C, YDR031W, YDR061W, YDR066C, YDR080W, YDR098C-A, YDR098C-B, YDR102C, YDR103W, YDR136C, YDR138W, YDR279W, YDR286C, YDR287W, YDR292C, YDR318W, YDR322W, YDR473C, YER013W, YER133W, YER134C, YER138C, YFL066C, YFL067W, YFR007W, YFR056C, YGL178W, YGL192W, YGL194C, YGR091W, YGR093W, YGR184C, YGR188C, YGR287C, YGR288W, YHL012W, YHL013C, YHL050C, YHR041C, YHR042W, YHR044C, YHR045W, YHR123W, YHR171W, YIL043C, YIL048W, YIL075C, YJL023C, YJR010C-A, YJR088C, YJR089W, YJR098C, YJR099W, YJR100C, YJR154W, YKR003W, YKR094C, YKR095W, YLL014W, YLR055C, YLR056W, YLR083C, YLR097C, YLR103C, YLR104W, YLR265C, YLR269C, YLR271W, YLR360W, YLR373C, YLR375W, YLR412W, YLR428C, YLR430W, YML072C, YML112W, YMR060C, YMR061W, YMR071C, YMR072W, YMR099C, YMR100W, YMR126C, YMR187C, YMR204C, YNL048W, YNL049C, YNL083W, YNL084C, YNL126W, YNL272C, YNL323W, YNL325C, YNR011C, YNR012W, YNR054C, YOL099C, YOL144W, YOL145C, YOR090C, YOR091W, YOR115C, YOR188W, YOR353C, YOR368W, YOR386W, YPL070W, YPL071C, YPL073C, YPL159C, YPR007C, YPR068C, YPR087W, YPR092W, YPR107C, YPR108W, YPR118W, YPR198W

Genes affected by TF deletion 53 genes

YDR068W, YKR012C, YHR146W, YJL115W, YDL127W, YMR189W, YPL014W, YML027W, YBR129C, YFR006W, YGR286C, YAR007C, YMR199W, YOR074C, YMR145C, YNR016C, YIL054W, YNL309W, YNR035C, YBR135W, YNL310C, YIR015W, YNL065W, YOL002C, YGL055W, YLR108C, YLR046C, YNL289W, YGR139W, YNL290W, YDR482C, YLL013C, YLL044W, YLR326W, YLR358C, YLR390W, YNL195C, YOR304C-A, YOR367W, YBL037W, YCL002C, YCL038C, YDR357C, YJL167W, YNR047W, YBR054W, YLR297W, YOR027W, YMR034C, YBR244W, YMR181C, YOL101C, YPL165C

Genes supported by both experiments 2 genes

YAR007C, YCL002C