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YHP1

YDR451C

View at SGD ↗

One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Macisaac et. al
Fisher’s P-value0.06083
Information content9.089
Max PWM score7.18
Recommended cutoff7.18
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.012 0.964 0.964 0.012 0.012 0.012 
C | 0.012 0.012 0.012 0.012 0.012 0.012 
G | 0.012 0.012 0.012 0.012 0.012 0.964 
T | 0.964 0.012 0.012 0.964 0.964 0.012 
Position count matrix (PCM)
A |   1  96  96   1   1   1 
C |   1   1   1   1   1   1 
G |   1   1   1   1   1  96 
T |  96   1   1  96  96   1 
Position weight matrix (PWM)
A | -3.28  1.10  1.10 -3.28 -3.28 -3.28 
C | -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 
G | -2.71 -2.71 -2.71 -2.71 -2.71  1.68 
T |  1.10 -3.28 -3.28  1.10  1.10 -3.28 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 3

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

YHP1Foat et. al.P = 0.006965View matrix ↘
Sequence logo for YHP1
Fisher’s P-value0.006965
Information content16.67
Max PWM score15.01
Recommended cutoff9.33
Position frequency matrix (PFM)
A | 0.58 0.01 0.01 0.05 0.01 0.01 0.18 0.97 0.01 0.11 0.01 0.32 0.97 
C | 0.03 0.92 0.74 0.01 0.01 0.02 0.55 0.01 0.01 0.87 0.01 0.26 0.01 
G | 0.01 0.01 0.25 0.01 0.01 0.96 0.26 0.01 0.03 0.01 0.43 0.34 0.01 
T | 0.39 0.05 0.01 0.94 0.97 0.01 0.01 0.01 0.95 0.01 0.56 0.08 0.01 
Position count matrix (PCM)
A |  57   1   1   5   1   1  18  97   1  11   1  32  97 
C |   3  92  74   1   1   2  55   1   1  87   1  26   1 
G |   1   1  25   1   1  96  26   1   3   1  43  34   1 
T |  39   5   1  94  97   1   1   1  95   1  56   8   1 
Position weight matrix (PWM)
A |  0.59 -3.47 -3.47 -1.86 -3.47 -3.47 -0.58  1.11 -3.47 -1.07 -3.47  0.00  1.11 
C | -1.79  1.63  1.41 -2.89 -2.89 -2.20  1.12 -2.89 -2.89  1.58 -2.89  0.37 -2.89 
G | -2.89 -2.89  0.33 -2.89 -2.89  1.67  0.37 -2.89 -1.79 -2.89  0.87  0.64 -2.89 
T |  0.20 -1.86 -3.47  1.08  1.11 -3.47 -3.47 -3.47  1.09 -3.47  0.56 -1.39 -3.47 
YHP1Harbison et. al.P = 0.06083View matrix ↘
Sequence logo for YHP1
Fisher’s P-value0.06083
Information content9.093
Max PWM score7.18
Recommended cutoff7.18
Position frequency matrix (PFM)
A | 0.012 0.964 0.964 0.012 0.012 0.012 
C | 0.012 0.012 0.012 0.012 0.012 0.012 
G | 0.012 0.012 0.012 0.012 0.012 0.965 
T | 0.964 0.012 0.012 0.964 0.964 0.012 
Position count matrix (PCM)
A |   1  96  96   1   1   1 
C |   1   1   1   1   1   1 
G |   1   1   1   1   1  96 
T |  96   1   1  96  96   1 
Position weight matrix (PWM)
A | -3.28  1.10  1.10 -3.28 -3.28 -3.28 
C | -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 
G | -2.71 -2.71 -2.71 -2.71 -2.71  1.68 
T |  1.10 -3.28 -3.28  1.10  1.10 -3.28 
YHP1Morozov et. al.P = 1View matrix ↘
Sequence logo for YHP1
Fisher’s P-value1
Information content9.339
Max PWM score16.98
Recommended cutoff8.54
Position frequency matrix (PFM)
A | 0.720 0.058 0.255 0.214 0.063 0.136 0.112 0.185 0.278 0.225 0.604 0.273 0.154 0.190 0.583 0.570 0.768 0.220 0.343 0.506 0.616 0.048 0.687 
C | 0.054 0.051 0.217 0.315 0.663 0.370 0.209 0.388 0.186 0.207 0.220 0.440 0.217 0.167 0.131 0.279 0.068 0.224 0.327 0.019 0.048 0.823 0.134 
G | 0.170 0.241 0.058 0.214 0.095 0.421 0.151 0.174 0.349 0.102 0.106 0.067 0.572 0.432 0.091 0.083 0.099 0.062 0.080 0.040 0.227 0.074 0.113 
T | 0.055 0.650 0.471 0.257 0.179 0.074 0.528 0.254 0.187 0.466 0.070 0.219 0.058 0.211 0.195 0.068 0.065 0.493 0.249 0.436 0.109 0.056 0.067 
Position count matrix (PCM)
A |  72   5  25  21   6  13  11  18  27  22  60  27  15  19  58  56  76  22  34  50  61   4  68 
C |   5   5  21  31  66  37  20  38  18  20  22  44  21  16  13  27   6  22  32   1   4  82  13 
G |  17  24   5  21   9  42  15  17  34  10  10   6  57  43   9   8   9   6   8   4  22   7  11 
T |   5  65  47  25  17   7  52  25  18  46   7  21   5  21  19   6   6  49  24  43  10   5   6 
Position weight matrix (PWM)
A |  0.81 -1.71 -0.23 -0.40 -1.63 -0.86 -1.05 -0.55 -0.14 -0.35  0.64 -0.16 -0.73 -0.52  0.60  0.58  0.88 -0.37  0.07  0.46  0.65 -1.90  0.76 
C | -1.20 -1.26  0.19  0.56  1.30  0.72  0.15  0.77  0.03  0.14  0.20  0.89  0.19 -0.07 -0.32  0.44 -0.97  0.22  0.60 -2.25 -1.32  1.52 -0.30 
G | -0.06  0.29 -1.13  0.17 -0.64  0.85 -0.18 -0.03  0.66 -0.57 -0.53 -0.99  1.16  0.88 -0.68 -0.77 -0.60 -1.07 -0.81 -1.50  0.23 -0.89 -0.47 
T | -1.76  0.71  0.39 -0.22 -0.58 -1.46  0.50 -0.23 -0.54  0.38 -1.52 -0.38 -1.71 -0.42 -0.50 -1.55 -1.59  0.43 -0.25  0.31 -1.08 -1.74 -1.56 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 92 genes

YAR009C, YAR018C, YBR174C, YBR176W, YBR248C, YBR292C, YCR028C, YDL017W, YDL018C, YDL064W, YDL065C, YDL092W, YDL094C, YDL146W, YDR028C, YDR029W, YDR080W, YDR117C, YDR118W, YDR127W, YDR136C, YDR138W, YDR190C, YDR191W, YDR210W-D, YDR273W, YDR279W, YEL032W, YER013W, YER133W, YER135C, YER138C, YFR023W, YGL137W, YGL138C, YGL159W, YGR004W, YGR056W, YGR092W, YGR150C, YHR001W, YHR028C, YHR062C, YIL048W, YIL075C, YJL037W, YJL038C, YJL145W, YJR010C-A, YKL161C, YKL177W, YKL179C, YLL016W, YLR011W, YLR020C, YLR021W, YLR085C, YLR086W, YLR222C, YLR275W, YLR311C, YLR312C, YLR312W-A, YLR330W, YMR106C, YMR197C, YMR198W, YMR257C, YMR270C, YMR283C, YNL131W, YNL187W, YNL210W, YNL211C, YNR006W, YNR067C, YOL115W, YOR004W, YOR059C, YOR102W, YOR148C, YOR188W, YOR214C, YOR297C, YOR298W, YOR353C, YPL159C, YPL208W, YPL209C, YPR047W, YPR092W, YPR118W

Genes affected by TF deletion 62 genes

YBR006W, YDR222W, YPL015C, YOR381W, YDR034C-A, YDR365W-B, YDR399W, YML113W, YPL014W, YPL016W, YLR374C, YMR103C, YGR250C, YLR120C, YNL303W, YNL305C, YJL017W, YMR104C, YDR340W, YLR121C, YCR021C, YDR074W, YOR267C, YPL247C, YKL051W, YLR251W, YML120C, YMR023C, YOR384W, YPR150W, YFR017C, YMR084W, YMR145C, YGR008C, YIR035C, YLR375W, YOL083W, YER064C, YNR034W, YPL087W, YOR273C, YGR138C, YLR414C, YOR019W, YNL033W, YGR139W, YOL158C, YNL160W, YBR054W, YLR297W, YEL067C, YLR428C, YDR055W, YMR034C, YBR214W, YMR181C, YMR250W, YOR092W, YGR057C, YCL040W, YHR110W, YNR019W