← All factors / TF RECORD

YAP6

YDR259C, HAL7

View at SGD ↗

Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation of expression of genes involved in carbohydrate metabolism

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Aligned Matrix
Fisher’s P-value9.74e-14
Information content8.662
Max PWM score9.9
Recommended cutoff6.04
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.102 0.009 0.889 0.005 0.424 0.035 0.885 0.734 0.323 0.151 
C | 0.067 0.020 0.036 0.834 0.031 0.075 0.068 0.052 0.217 0.657 
G | 0.086 0.017 0.038 0.020 0.536 0.055 0.022 0.044 0.224 0.074 
T | 0.745 0.956 0.037 0.143 0.009 0.834 0.026 0.171 0.236 0.118 
Position count matrix (PCM)
A |  10   0  88   0  42   3  88  73  32  15 
C |   6   2   3  83   3   7   6   5  21  65 
G |   8   1   3   2  53   5   2   4  22   7 
T |  74  95   3  14   0  83   2  17  23  11 
Position weight matrix (PWM)
A | -1.14 -3.57  1.02 -4.16  0.28 -2.21  1.02  0.83  0.01 -0.75 
C | -0.99 -2.20 -1.61  1.53 -1.76 -0.88 -0.97 -1.24  0.19  1.29 
G | -0.74 -2.36 -1.56 -2.20  1.09 -1.19 -2.10 -1.41  0.22 -0.89 
T |  0.85  1.09 -2.16 -0.81 -3.57  0.96 -2.51 -0.63 -0.30 -1.00 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 8

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

YAP6_AFoat et. al.P = 7.42e-07View matrix ↘
Sequence logo for YAP6_A
Fisher’s P-value7.42e-07
Information content17.44
Max PWM score14.74
Recommended cutoff8.52
Position frequency matrix (PFM)
A | 0.01 0.69 0.74 0.01 0.11 0.01 0.01 0.97 0.01 0.04 0.51 0.01 0.63 
C | 0.01 0.01 0.15 0.01 0.52 0.01 0.01 0.01 0.01 0.94 0.21 0.97 0.01 
G | 0.01 0.27 0.10 0.97 0.37 0.01 0.44 0.01 0.97 0.01 0.20 0.01 0.36 
T | 0.97 0.03 0.01 0.01 0.01 0.97 0.55 0.01 0.01 0.01 0.08 0.01 0.01 
Position count matrix (PCM)
A |   1  69  74   1  11   1   1  97   1   4  51   1  63 
C |   1   1  15   1  52   1   1   1   1  94  21  97   1 
G |   1  27  10  97  37   1  44   1  97   1  20   1  36 
T |  97   3   1   1   1  97  55   1   1   1   8   1   1 
Position weight matrix (PWM)
A | -3.47  0.77  0.84 -3.47 -1.07 -3.47 -3.47  1.11 -3.47 -2.08  0.47 -3.47  0.68 
C | -2.89 -2.89 -0.18 -2.89  1.06 -2.89 -2.89 -2.89 -2.89  1.65  0.15  1.68 -2.89 
G | -2.89  0.41 -0.59  1.68  0.72 -2.89  0.89 -2.89  1.68 -2.89  0.11 -2.89  0.69 
T |  1.11 -2.37 -3.47 -3.47 -3.47  1.11  0.54 -3.47 -3.47 -3.47 -1.39 -3.47 -3.47 
YAP6_BFoat et. al.P = 1View matrix ↘
Sequence logo for YAP6_B
Fisher’s P-value1
Information content21.4
Max PWM score23.66
Recommended cutoff17.75
Position frequency matrix (PFM)
A | 0.42 0.79 0.40 0.97 0.01 0.01 0.05 0.23 0.39 0.22 0.11 0.10 0.08 0.83 0.18 0.27 0.01 0.15 0.01 0.02 0.01 0.34 0.31 0.59 
C | 0.02 0.01 0.23 0.01 0.01 0.03 0.68 0.01 0.13 0.01 0.84 0.14 0.51 0.01 0.36 0.51 0.11 0.29 0.01 0.01 0.97 0.57 0.03 0.04 
G | 0.34 0.20 0.33 0.01 0.01 0.95 0.20 0.62 0.24 0.32 0.03 0.30 0.27 0.15 0.16 0.05 0.87 0.26 0.01 0.01 0.01 0.01 0.01 0.15 
T | 0.23 0.01 0.03 0.01 0.97 0.01 0.07 0.15 0.24 0.46 0.02 0.46 0.13 0.01 0.31 0.17 0.01 0.31 0.97 0.96 0.01 0.08 0.65 0.23 
Position count matrix (PCM)
A |  42  79  40  97   1   1   5  23  39  22  11  10   8  83  18  27   1  15   1   2   1  34  31  59 
C |   2   1  23   1   1   3  68   1  13   1  84  14  51   1  36  51  11  28   1   1  97  56   3   4 
G |  34  20  33   1   1  95  20  62  24  32   3  30  27  15  16   5  87  26   1   1   1   1   1  15 
T |  23   1   3   1  97   1   7  15  24  46   2  46  13   1  31  17   1  31  97  96   1   8  65  23 
Position weight matrix (PWM)
A |  0.27  0.90  0.22  1.11 -3.47 -3.47 -1.86 -0.33  0.20 -0.37 -1.07 -1.16 -1.39  0.95 -0.58 -0.17 -3.47 -0.76 -3.47 -2.77 -3.47  0.06 -0.03  0.61 
C | -2.20 -2.89  0.25 -2.89 -2.89 -1.79  1.33 -2.89 -0.33 -2.89  1.54 -0.25  1.04 -2.89  0.69  1.04 -0.49  0.48 -2.89 -2.89  1.68  1.15 -1.79 -1.50 
G |  0.64  0.11  0.61 -2.89 -2.89  1.66  0.11  1.24  0.29  0.58 -1.79  0.51  0.41 -0.18 -0.12 -1.28  1.58  0.37 -2.89 -2.89 -2.89 -2.89 -2.89 -0.18 
T | -0.33 -3.47 -2.37 -3.47  1.11 -3.47 -1.52 -0.76 -0.29  0.36 -2.77  0.36 -0.90 -3.47 -0.03 -0.63 -3.47 -0.03  1.11  1.10 -3.47 -1.39  0.71 -0.33 
YAP6_CFoat et. al.P = 2.35e-06View matrix ↘
Sequence logo for YAP6_C
Fisher’s P-value2.35e-06
Information content16.2
Max PWM score14.94
Recommended cutoff11.62
Position frequency matrix (PFM)
A | 0.42 0.03 0.97 0.83 0.01 0.16 0.68 0.86 0.85 0.01 0.02 0.01 0.01 
C | 0.06 0.01 0.01 0.01 0.04 0.64 0.30 0.07 0.01 0.01 0.01 0.01 0.25 
G | 0.52 0.85 0.01 0.01 0.94 0.20 0.01 0.06 0.11 0.97 0.01 0.10 0.01 
T | 0.01 0.12 0.01 0.16 0.01 0.01 0.01 0.01 0.03 0.01 0.96 0.88 0.74 
Position count matrix (PCM)
A |  42   3  97  83   1  16  68  86  85   1   2   1   1 
C |   6   1   1   1   4  64  30   7   1   1   1   1  25 
G |  52  85   1   1  94  20   1   6  11  97   1  10   1 
T |   1  12   1  16   1   1   1   1   3   1  96  88  74 
Position weight matrix (PWM)
A |  0.27 -2.37  1.11  0.95 -3.47 -0.69  0.75  0.99  0.98 -3.47 -2.77 -3.47 -3.47 
C | -1.10 -2.89 -2.89 -2.89 -1.50  1.27  0.51 -0.94 -2.89 -2.89 -2.89 -2.89  0.33 
G |  1.06  1.55 -2.89 -2.89  1.65  0.11 -2.89 -1.10 -0.49  1.68 -2.89 -0.59 -2.89 
T | -3.47 -0.98 -3.47 -0.69 -3.47 -3.47 -3.47 -3.47 -2.37 -3.47  1.10  1.01  0.84 
YAP6Harbison et. al.P = 3.30e-05View matrix ↘
Sequence logo for YAP6
Fisher’s P-value3.30e-05
Information content10.48
Max PWM score8.28
Recommended cutoff4.47
Position frequency matrix (PFM)
A | 0.012 0.012 0.964 0.012 0.012 0.964 0.964 
C | 0.012 0.012 0.012 0.965 0.012 0.012 0.012 
G | 0.012 0.012 0.012 0.012 0.012 0.012 0.012 
T | 0.964 0.964 0.012 0.012 0.964 0.012 0.012 
Position count matrix (PCM)
A |   1   1  96   1   1  96  96 
C |   1   1   1  96   1   1   1 
G |   1   1   1   1   1   1   1 
T |  96  96   1   1  96   1   1 
Position weight matrix (PWM)
A | -3.28 -3.28  1.10 -3.28 -3.28  1.10  1.10 
C | -2.71 -2.71 -2.71  1.68 -2.71 -2.71 -2.71 
G | -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 
T |  1.10  1.10 -3.28 -3.28  1.10 -3.28 -3.28 
YAP6Macisaac et. alP = 2.47e-09View matrix ↘
Sequence logo for YAP6
Fisher’s P-value2.47e-09
Information content8.462
Max PWM score7.93
Recommended cutoff7.76
Position frequency matrix (PFM)
A | 0.147 0.001 0.972 0.001 0.660 0.009 0.780 0.606 
C | 0.037 0.037 0.001 0.944 0.001 0.028 0.055 0.156 
G | 0.156 0.001 0.018 0.009 0.311 0.009 0.046 0.055 
T | 0.660 0.961 0.009 0.046 0.028 0.954 0.119 0.183 
Position count matrix (PCM)
A |  14   0  97   0  66   0  78  60 
C |   3   3   0  94   0   2   5  15 
G |  15   0   1   0  31   0   4   5 
T |  66  96   0   4   2  95  11  18 
Position weight matrix (PWM)
A | -0.78 -5.77  1.11 -5.77  0.72 -3.57  0.89  0.64 
C | -1.58 -1.58 -5.19  1.66 -5.19 -1.86 -1.19 -0.14 
G | -0.14 -5.19 -2.30 -3.00  0.55 -3.00 -1.36 -1.19 
T |  0.72  1.10 -3.57 -1.94 -2.44  1.09 -0.99 -0.56 
YAP6Morozov et. al.P = 4.32e-13View matrix ↘
Sequence logo for YAP6
Fisher’s P-value4.32e-13
Information content8.963
Max PWM score10.08
Recommended cutoff6.21
Position frequency matrix (PFM)
A | 0.095 0.010 0.877 0.005 0.390 0.039 0.900 0.752 0.323 0.127 
C | 0.071 0.017 0.041 0.818 0.035 0.082 0.070 0.037 0.222 0.725 
G | 0.076 0.019 0.040 0.021 0.569 0.062 0.018 0.042 0.230 0.059 
T | 0.757 0.955 0.041 0.156 0.006 0.817 0.012 0.169 0.224 0.089 
Position count matrix (PCM)
A |   9   1  87   0  39   3  90  75  32  12 
C |   7   1   4  81   3   8   7   3  22  72 
G |   7   1   4   2  56   6   1   4  23   5 
T |  75  95   4  15   0  81   1  16  22   8 
Position weight matrix (PWM)
A | -1.21 -3.47  1.01 -4.16  0.20 -2.10  1.03  0.85  0.01 -0.92 
C | -0.93 -2.36 -1.48  1.51 -1.64 -0.79 -0.94 -1.58  0.21  1.39 
G | -0.86 -2.25 -1.50 -2.15  1.15 -1.07 -2.30 -1.46  0.25 -1.12 
T |  0.86  1.09 -2.05 -0.72 -3.98  0.94 -3.28 -0.64 -0.36 -1.28 
YAP6Zhu et. al.P = 4.68e-09View matrix ↘
Sequence logo for YAP6
Fisher’s P-value4.68e-09
Information content9.581
Max PWM score13.21
Recommended cutoff6.66
Position frequency matrix (PFM)
A | 0.23 0.13 0.11 0.25 0.04 0.49 0.03 0.03 0.89 0.04 0.17 0.07 0.65 0.83 
C | 0.14 0.09 0.43 0.23 0.11 0.41 0.02 0.02 0.03 0.56 0.05 0.09 0.19 0.06 
G | 0.59 0.33 0.11 0.07 0.65 0.04 0.06 0.11 0.05 0.10 0.72 0.04 0.06 0.07 
T | 0.04 0.44 0.34 0.44 0.20 0.06 0.89 0.84 0.03 0.30 0.06 0.81 0.10 0.03 
Position count matrix (PCM)
A |  23  13  11  25   4  49   3   3  89   4  17   7  65  83 
C |  14   9  43  23  11  41   2   2   3  56   5   9  19   6 
G |  59  33  11   7  65   4   6  11   5  10  72   4   6   7 
T |   4  44  34  44  20   6  89  84   3  30   6  81  10   3 
Position weight matrix (PWM)
A | -0.33 -0.90 -1.07 -0.25 -2.08  0.43 -2.37 -2.37  1.02 -2.08 -0.63 -1.52  0.71  0.95 
C | -0.25 -0.69  0.87  0.25 -0.49  0.82 -2.20 -2.20 -1.79  1.13 -1.28 -0.69  0.05 -1.10 
G |  1.19  0.61 -0.49 -0.94  1.28 -1.50 -1.10 -0.49 -1.28 -0.59  1.39 -1.50 -1.10 -0.94 
T | -2.08  0.32  0.06  0.32 -0.47 -1.67  1.02  0.97 -2.37 -0.06 -1.67  0.93 -1.16 -2.37 
YAP6Zhao and StormoP = 1View matrix ↘
Sequence logo for YAP6
Fisher’s P-value1
Information content0.7224
Max PWM score3.75
Recommended cutoff3.25
Position frequency matrix (PFM)
A | 0.259 0.248 0.293 0.279 0.285 0.265 0.296 0.455 
C | 0.216 0.217 0.228 0.224 0.209 0.198 0.207 0.129 
G | 0.310 0.299 0.260 0.271 0.282 0.290 0.293 0.296 
T | 0.216 0.236 0.219 0.226 0.224 0.247 0.204 0.119 
Position count matrix (PCM)
A |  25  24  29  27  28  26  29  45 
C |  21  21  22  22  20  19  20  12 
G |  31  29  26  27  28  28  29  29 
T |  21  23  21  22  22  24  20  11 
Position weight matrix (PWM)
A | -0.21 -0.25 -0.09 -0.14 -0.12 -0.19 -0.08  0.35 
C |  0.18  0.19  0.24  0.22  0.15  0.10  0.14 -0.33 
G |  0.54  0.51  0.37  0.41  0.45  0.48  0.49  0.50 
T | -0.39 -0.30 -0.38 -0.35 -0.36 -0.26 -0.45 -0.99 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 167 genes

YAL064W, YBL029W, YBL030C, YBR157C, YBR158W, YDL037C, YDL245C, YDL246C, YDR042C, YDR077W, YDR259C, YDR441C, YDR442W, YDR524C, YDR525W, YEL006W, YEL007W, YEL040W, YEL044W, YEL045C, YEL046C, YEL047C, YEL055C, YEL069C, YEL070W, YER001W, YER007C-A, YER028C, YER045C, YER073W, YER158C, YFL004W, YFL034C-B, YGL005C, YGL135W, YGL136C, YGL158W, YGR035C, YGR060W, YGR108W, YGR190C, YGR192C, YGR221C, YGR234W, YGR238C, YGR249W, YHL034C, YHL041W, YHR047C, YHR049W, YIL012W, YIL013C, YIL015C-A, YIL056W, YIL099W, YIL118W, YIL119C, YIL122W, YIL170W, YIL171W, YIL172C, YIR013C, YIR014W, YIR017C, YIR018W, YIR019C, YIR020C, YIR021W, YIR022W, YIR023W, YIR034C, YIR035C, YIR038C, YJL048C, YJL105W, YJL148W, YJL191W, YJL192C, YJL216C, YJL217W, YJL219W, YJL221C, YJR094C, YJR094W-A, YJR100C, YJR145C, YJR146W, YJR147W, YJR158W, YJR159W, YKL044W, YKL109W, YKL110C, YKR039W, YKR102W, YLL052C, YLL053C, YLR028C, YLR074C, YLR075W, YLR081W, YLR105C, YLR121C, YLR294C, YLR295C, YLR296W, YLR304C, YLR354C, YLR367W, YLR368W, YLR413W, YML116W, YML131W, YMR014W, YMR017W, YMR082C, YMR125W, YMR135C, YMR136W, YMR319C, YMR320W, YNL066W, YNL087W, YNL145W, YNL178W, YNL179C, YNL180C, YNL337W, YNL338W, YNL339C, YNR050C, YNR067C, YOL121C, YOL151W, YOL154W, YOL155C, YOL156W, YOL157C, YOL158C, YOR028C, YOR029W, YOR032C, YOR042W, YOR049C, YOR153W, YOR167C, YOR168W, YOR170W, YOR178C, YOR179C, YOR180C, YOR181W, YOR223W, YOR236W, YOR272W, YOR277C, YOR278W, YOR315W, YOR369C, YOR381W, YPL143W, YPL198W, YPR013C, YPR065W, YPR148C, YPR149W, YPR192W

Genes affected by TF deletion 22 genes

YMR192W, YBL097W, YFL013W-A, YGL075C, YKL139W, YBR093C, YDR281C, YHR127W, YOR043W, YJR148W, YFL051C, YOR141C, YDL233W, YER159C, YBR144C, YPL130W, YGR016W, YGL191W, YKR101W, YDR061W, YMR034C, YDR485C