← All factors / TF RECORD
XBP1
YIL101C
Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate
01 / RECOMMENDED MATRIX
Best-performing DNA-binding model.
Fisher’s P-value4.11e-12
Information content12.73
Max PWM score12.44
Recommended cutoff6.9
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.01 0.05 0.03 0.01 0.01 0.85 0.15 0.30 0.81 0.29 C | 0.14 0.63 0.01 0.97 0.01 0.01 0.01 0.01 0.16 0.08 G | 0.69 0.01 0.01 0.01 0.97 0.01 0.83 0.68 0.01 0.03 T | 0.16 0.31 0.95 0.01 0.01 0.13 0.01 0.01 0.02 0.60
Position count matrix (PCM)
A | 1 5 3 1 1 85 15 30 81 28 C | 14 63 1 97 1 1 1 1 16 8 G | 69 1 1 1 97 1 83 68 1 3 T | 16 31 95 1 1 13 1 1 2 60
Position weight matrix (PWM)
A | -3.47 -1.86 -2.37 -3.47 -3.47 0.98 -0.76 -0.06 0.93 -0.10 C | -0.25 1.25 -2.89 1.68 -2.89 -2.89 -2.89 -2.89 -0.12 -0.81 G | 1.34 -2.89 -2.89 -2.89 1.68 -2.89 1.53 1.33 -2.89 -1.79 T | -0.69 -0.03 1.09 -3.47 -3.47 -0.90 -3.47 -3.47 -2.77 0.63
02 / COMPARATIVE BENCHMARKS
Alternative candidate matrices 7
Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.
XBP1Badis et. al.P = 4.08e-09View matrix ↘
Fisher’s P-value4.08e-09
Information content8.395
Max PWM score7.62
Recommended cutoff7.62
Position frequency matrix (PFM)
A | 0.12 0.01 0.01 0.01 0.97 0.40 C | 0.50 0.01 0.97 0.01 0.01 0.08 G | 0.07 0.01 0.01 0.97 0.01 0.50 T | 0.31 0.97 0.01 0.01 0.01 0.03
Position count matrix (PCM)
A | 12 1 1 1 97 40 C | 50 1 97 1 1 8 G | 7 1 1 97 1 50 T | 31 97 1 1 1 3
Position weight matrix (PWM)
A | -0.98 -3.47 -3.47 -3.47 1.11 0.22 C | 1.02 -2.89 1.68 -2.89 -2.89 -0.81 G | -0.94 -2.89 -2.89 1.68 -2.89 1.02 T | -0.03 1.11 -3.47 -3.47 -3.47 -2.37
XBP1_BFoat et. al.P = 0.08952View matrix ↘
Fisher’s P-value0.08952
Information content16.32
Max PWM score14.29
Recommended cutoff7.73
Position frequency matrix (PFM)
A | 0.01 0.71 0.19 0.90 0.01 0.25 0.01 0.97 0.01 0.03 0.01 0.10 C | 0.33 0.01 0.01 0.01 0.97 0.01 0.97 0.01 0.97 0.01 0.29 0.08 G | 0.01 0.22 0.36 0.08 0.01 0.26 0.01 0.01 0.01 0.93 0.70 0.80 T | 0.66 0.06 0.45 0.01 0.01 0.48 0.01 0.01 0.01 0.02 0.01 0.02
Position count matrix (PCM)
A | 1 71 19 90 1 25 1 97 1 3 1 10 C | 33 1 1 1 97 1 97 1 97 1 28 8 G | 1 22 36 8 1 26 1 1 1 93 70 80 T | 66 6 45 1 1 48 1 1 1 2 1 2
Position weight matrix (PWM)
A | -3.47 0.80 -0.52 1.03 -3.47 -0.25 -3.47 1.11 -3.47 -2.37 -3.47 -1.16 C | 0.61 -2.89 -2.89 -2.89 1.68 -2.89 1.68 -2.89 1.68 -2.89 0.48 -0.81 G | -2.89 0.20 0.69 -0.81 -2.89 0.37 -2.89 -2.89 -2.89 1.64 1.36 1.49 T | 0.72 -1.67 0.34 -3.47 -3.47 0.41 -3.47 -3.47 -3.47 -2.77 -3.47 -2.77
XBP1Harbison et. al.P = 2.57e-08View matrix ↘
Fisher’s P-value2.57e-08
Information content12.87
Max PWM score10.02
Recommended cutoff5.64
Position frequency matrix (PFM)
A | 0.012 0.012 0.012 0.012 0.012 0.965 0.012 C | 0.965 0.012 0.012 0.965 0.012 0.012 0.012 G | 0.012 0.012 0.012 0.012 0.965 0.012 0.965 T | 0.012 0.965 0.965 0.012 0.012 0.012 0.012
Position count matrix (PCM)
A | 1 1 1 1 1 96 1 C | 96 1 1 96 1 1 1 G | 1 1 1 1 96 1 96 T | 1 96 96 1 1 1 1
Position weight matrix (PWM)
A | -3.28 -3.28 -3.28 -3.28 -3.28 1.10 -3.28 C | 1.68 -2.71 -2.71 1.68 -2.71 -2.71 -2.71 G | -2.71 -2.71 -2.71 -2.71 1.68 -2.71 1.68 T | -3.28 1.10 1.10 -3.28 -3.28 -3.28 -3.28
XBP1Macisaac et. alP = 1.30e-10View matrix ↘
Fisher’s P-value1.30e-10
Information content11.32
Max PWM score10.3
Recommended cutoff8.4
Position frequency matrix (PFM)
A | 0.001 0.001 0.113 0.032 0.967 0.210 0.032 0.484 C | 0.676 0.016 0.854 0.016 0.001 0.001 0.032 0.210 G | 0.113 0.001 0.001 0.936 0.016 0.788 0.935 0.129 T | 0.210 0.982 0.032 0.016 0.016 0.001 0.001 0.177
Position count matrix (PCM)
A | 0 0 11 3 96 21 3 48 C | 67 1 85 1 0 0 3 21 G | 11 0 0 93 1 78 93 12 T | 21 98 3 1 1 0 0 17
Position weight matrix (PWM)
A | -5.77 -5.77 -1.04 -2.30 1.11 -0.42 -2.30 0.41 C | 1.32 -2.42 1.56 -2.42 -5.19 -5.19 -1.73 0.15 G | -0.47 -5.19 -5.19 1.65 -2.42 1.48 1.65 -0.33 T | -0.42 1.12 -2.30 -3.00 -3.00 -5.77 -5.77 -0.59
XBP1Zhu J and MQ ZhangP = 6.03e-08View matrix ↘
Fisher’s P-value6.03e-08
Information content10.64
Max PWM score13.31
Recommended cutoff7.11
Position frequency matrix (PFM)
A | 0.20 0.20 0.07 0.02 0.02 0.02 0.78 0.39 0.15 0.39 0.15 0.44 C | 0.15 0.39 0.73 0.02 0.93 0.02 0.02 0.05 0.15 0.46 0.24 0.12 G | 0.54 0.24 0.15 0.02 0.02 0.93 0.17 0.49 0.68 0.07 0.44 0.34 T | 0.12 0.17 0.05 0.93 0.02 0.02 0.02 0.07 0.02 0.07 0.17 0.10
Position count matrix (PCM)
A | 20 20 7 2 2 2 78 39 15 39 15 44 C | 15 39 73 2 93 2 2 5 15 46 24 12 G | 54 24 15 2 2 93 17 49 68 7 44 34 T | 12 17 5 93 2 2 2 7 2 7 17 10
Position weight matrix (PWM)
A | -0.47 -0.47 -1.52 -2.77 -2.77 -2.77 0.89 0.20 -0.76 0.20 -0.76 0.32 C | -0.18 0.77 1.40 -2.20 1.64 -2.20 -2.20 -1.28 -0.18 0.94 0.29 -0.41 G | 1.10 0.29 -0.18 -2.20 -2.20 1.64 -0.06 1.00 1.33 -0.94 0.89 0.64 T | -0.98 -0.63 -1.86 1.07 -2.77 -2.77 -2.77 -1.52 -2.77 -1.52 -0.63 -1.16
XBP1Zhu et. al.P = 6.41e-12View matrix ↘
Fisher’s P-value6.41e-12
Information content10.7
Max PWM score11.31
Recommended cutoff7.26
Position frequency matrix (PFM)
A | 0.07 0.02 0.01 0.01 0.02 0.95 0.28 0.52 0.27 0.42 0.08 C | 0.34 0.68 0.03 0.96 0.01 0.01 0.02 0.07 0.13 0.16 0.23 G | 0.07 0.02 0.01 0.01 0.96 0.03 0.68 0.34 0.36 0.32 0.12 T | 0.52 0.28 0.95 0.02 0.01 0.01 0.02 0.07 0.24 0.10 0.57
Position count matrix (PCM)
A | 7 2 1 1 2 95 28 52 27 42 8 C | 34 68 3 96 1 1 2 7 13 16 23 G | 7 2 1 1 96 3 68 34 36 32 12 T | 52 28 95 2 1 1 2 7 24 10 56
Position weight matrix (PWM)
A | -1.52 -2.77 -3.47 -3.47 -2.77 1.09 -0.13 0.49 -0.17 0.27 -1.39 C | 0.64 1.33 -1.79 1.67 -2.89 -2.89 -2.20 -0.94 -0.33 -0.12 0.25 G | -0.94 -2.20 -2.89 -2.89 1.67 -1.79 1.33 0.64 0.69 0.58 -0.41 T | 0.49 -0.13 1.09 -2.77 -3.47 -3.47 -2.77 -1.52 -0.29 -1.16 0.58
XBP1Zhao and StormoP = 6.47e-08View matrix ↘
Fisher’s P-value6.47e-08
Information content4.783
Max PWM score5.67
Recommended cutoff5.67
Position frequency matrix (PFM)
A | 0.071 0.066 0.026 0.066 0.708 C | 0.453 0.136 0.847 0.068 0.045 G | 0.062 0.036 0.035 0.836 0.175 T | 0.414 0.761 0.092 0.030 0.072
Position count matrix (PCM)
A | 7 6 2 6 70 C | 45 13 84 6 4 G | 6 3 3 83 17 T | 41 76 9 3 7
Position weight matrix (PWM)
A | -1.51 -1.58 -2.51 -1.58 0.79 C | 0.92 -0.28 1.55 -0.97 -1.39 G | -1.07 -1.61 -1.64 1.54 -0.03 T | 0.26 0.87 -1.25 -2.37 -1.49
03 / EXPERIMENTAL CONTEXT
Gene-level annotations and interactions.
Genes bound in ChIP-chip experiments 25 genes
YAL009W, YAL010C, YAL011W, YAR010C, YBL027W, YBL028C, YBR127C, YDL215C, YDR019C, YDR451C, YDR452W, YFR016C, YHR051W, YHR193C, YHR194W, YIL018W, YIR017C, YIR018W, YJL045W, YJL112W, YLL037W, YLL039C, YLR143W, YMR183C, YMR184W
Genes affected by TF deletion 41 genes
YKL111C, YLR025W, YLR436C, YNL211C, YPL017C, YPL049C, YNL019C, YPL016W, YPR109W, YHR085W, YIR034C, YBR093C, YFR006W, YDR281C, YLR119W, YJR148W, YLR099C, YPL058C, YBR291C, YBR046C, YNL065W, YKL090W, YPL066W, YPL063W, YHR097C, YKL001C, YPL162C, YHR068W, YPL095C, YFL008W, YMR034C, YOR212W, YHR135C, YHR140W, YLR113W, YNL296W, YOL160W, YDL216C, YDR485C, YNR050C, YNL328C
Predicted TF–TF partners 3 genes
HSF1, MOT2, STB3