S.ScerTFYeast transcription factor database Aaron Spivak
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UPC2

YDR213W, MOX4

View at SGD ↗

Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of DAN/TIR gene products; Ecm22p homolog; relocates from intracellular membranes to perinuclear foci on sterol depletion

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Foat et. al.
Fisher’s P-value0.0006282
Information content17.17
Max PWM score14.72
Recommended cutoff9.95
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.61 0.01 0.01 0.02 0.95 0.01 0.01 0.01 0.01 0.01 0.04 0.01 
C | 0.01 0.39 0.15 0.01 0.01 0.97 0.95 0.01 0.04 0.18 0.01 0.45 
G | 0.37 0.01 0.01 0.96 0.01 0.01 0.01 0.01 0.94 0.75 0.01 0.26 
T | 0.01 0.60 0.84 0.01 0.03 0.01 0.03 0.97 0.01 0.07 0.94 0.28
Position count matrix (PCM)
A |  61   1   1   2  95   1   1   1   1   1   4   1 
C |   1  39  15   1   1  97  95   1   4  18   1  45 
G |  37   1   1  96   1   1   1   1  94  75   1  26 
T |   1  60  84   1   3   1   3  97   1   7  94  28
Position weight matrix (PWM)
A |  0.65 -3.47 -3.47 -2.77  1.09 -3.47 -3.47 -3.47 -3.47 -3.47 -2.08 -3.47 
C | -2.89  0.77 -0.18 -2.89 -2.89  1.68  1.66 -2.89 -1.50  0.00 -2.89  0.92 
G |  0.72 -2.89 -2.89  1.67 -2.89 -2.89 -2.89 -2.89  1.65  1.43 -2.89  0.37 
T | -3.47  0.63  0.97 -3.47 -2.37 -3.47 -2.37  1.11 -3.47 -1.52  1.08 -0.13
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 1

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

UPC2Badis et. al.P = 0.0454View matrix ↘
Sequence logo for UPC2
Fisher’s P-value0.0454
Information content7.7
Max PWM score6.67
Recommended cutoff4.45
Position frequency matrix (PFM)
A | 0.59 0.37 0.97 0.01 0.01 0.82 
C | 0.03 0.01 0.01 0.97 0.01 0.05 
G | 0.29 0.01 0.01 0.01 0.97 0.09 
T | 0.09 0.61 0.01 0.01 0.01 0.04
Position count matrix (PCM)
A |  59  37  97   1   1  82 
C |   3   1   1  97   1   5 
G |  28   1   1   1  97   9 
T |   9  61   1   1   1   4
Position weight matrix (PWM)
A |  0.61  0.15  1.11 -3.47 -3.47  0.94 
C | -1.79 -2.89 -2.89  1.68 -2.89 -1.28 
G |  0.48 -2.89 -2.89 -2.89  1.68 -0.69 
T | -1.27  0.65 -3.47 -3.47 -3.47 -2.08
Badis et. al.
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 120 genes

YAR009C, YBR109C, YBR110W, YBR159W, YBR163W, YCL002C, YCL006C, YCL007C, YCL008C, YCL009C, YCL010C, YCR002C, YCR004C, YCR005C, YCR006C, YCR008W, YCR012W, YCR032W, YDL013W, YDL092W, YDL094C, YDL179W, YDR045C, YDR056C, YDR057W, YDR066C, YDR075W, YDR080W, YDR179C, YDR179W-A, YDR183W, YDR210W-D, YDR279W, YDR282C, YDR286C, YDR287W, YDR294C, YDR370C, YDR371W, YDR372C, YDR373W, YDR404C, YDR405W, YDR472W, YER044C, YER066C-A, YER068W, YER138C, YFR007W, YFR041C, YFR042W, YGL116W, YGR004W, YGR126W, YGR187C, YGR188C, YGR200C, YHR171W, YHR209W, YIL014W, YIL048W, YIL139C, YJL094C, YJL193W, YJL195C, YJR012C, YJR013W, YJR088C, YJR089W, YJR098C, YJR099W, YJR100C, YJR102C, YJR103W, YJR108W, YJR132W, YJR142W, YJR154W, YKL039W, YKL040C, YKL077W, YLL014W, YLR097C, YLR269C, YLR271W, YLR446W, YMR052W, YMR125W, YMR193W, YNL012W, YNL013C, YNL076W, YNL258C, YNL284C, YNR011C, YNR012W, YNR054C, YOL024W, YOL049W, YOL050C, YOL102C, YOR102W, YOR115C, YOR209C, YOR210W, YOR263C, YOR265W, YOR280C, YOR282W, YOR309C, YOR310C, YOR365C, YOR367W, YOR368W, YPL113C, YPL208W, YPL209C, YPR122W, YPR139C, YPR140W

Genes affected by TF deletion 23 genes

YMR220W, YER011W, YMR134W, YDR314C, YBR093C, YFR006W, YNL300W, YLR100W, YOL053W, YLR099C, YLR101C, YOR010C, YKR055W, YML012W, YML097C, YHR189W, YGR176W, YDR213W, YGR177C, YLR366W, YOR306C, YBL018C, YER077C

Predicted TF–TF partners 1 genes

TEC1

Explore 1 original interaction plots →