← All factors / TF RECORD

UME1

YPL139C, WTM3

View at SGD ↗

Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Harbison et. al.
Fisher’s P-value1.46e-11
Information content12.15
Max PWM score11
Recommended cutoff8.96
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.868 0.797 0.011 0.011 0.797 0.976 0.976 0.404 0.011 0.404 0.976 
C | 0.007 0.007 0.007 0.007 0.007 0.007 0.007 0.221 0.007 0.007 0.007 
G | 0.114 0.007 0.543 0.971 0.185 0.007 0.007 0.185 0.614 0.007 0.007 
T | 0.011 0.190 0.440 0.011 0.011 0.011 0.011 0.190 0.368 0.583 0.011 
Position count matrix (PCM)
A |  86  79   1   1  79  97  97  40   1  40  97 
C |   0   0   0   0   0   0   0  22   0   0   0 
G |  11   0  54  97  18   0   0  18  61   0   0 
T |   1  19  44   1   1   1   1  19  36  58   1 
Position weight matrix (PWM)
A |  1.00  0.91 -3.37 -3.37  0.91  1.12  1.12  0.23 -3.37  0.23  1.12 
C | -3.25 -3.25 -3.25 -3.25 -3.25 -3.25 -3.25  0.21 -3.25 -3.25 -3.25 
G | -0.46 -3.25  1.10  1.69  0.03 -3.25 -3.25  0.03  1.23 -3.25 -3.25 
T | -3.37 -0.52  0.32 -3.37 -3.37 -3.37 -3.37 -0.52  0.14  0.60 -3.37 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 2

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

UME1_AFoat et. al.P = 3.73e-05View matrix ↘
Sequence logo for UME1_A
Fisher’s P-value3.73e-05
Information content17.31
Max PWM score18.71
Recommended cutoff9.88
Position frequency matrix (PFM)
A | 0.53 0.30 0.07 0.97 0.01 0.01 0.42 0.71 0.39 0.10 0.01 0.56 0.06 0.04 0.91 0.01 0.59 0.38 0.39 
C | 0.02 0.33 0.08 0.01 0.01 0.01 0.38 0.03 0.60 0.01 0.55 0.01 0.05 0.02 0.01 0.97 0.18 0.01 0.30 
G | 0.45 0.32 0.68 0.01 0.97 0.20 0.04 0.01 0.01 0.39 0.15 0.43 0.55 0.02 0.07 0.01 0.10 0.01 0.01 
T | 0.01 0.05 0.17 0.01 0.01 0.78 0.16 0.25 0.01 0.51 0.30 0.01 0.35 0.92 0.01 0.01 0.13 0.60 0.30 
Position count matrix (PCM)
A |  53  30   7  97   1   1  42  71  39  10   1  56   6   4  91   1  59  38  39 
C |   2  33   8   1   1   1  38   3  60   1  55   1   5   2   1  97  18   1  30 
G |  45  32  68   1  97  20   4   1   1  39  15  43  55   2   7   1  10   1   1 
T |   1   5  17   1   1  78  16  25   1  51  30   1  35  92   1   1  13  60  30 
Position weight matrix (PWM)
A |  0.50 -0.06 -1.52  1.11 -3.47 -3.47  0.27  0.80  0.20 -1.16 -3.47  0.56 -1.67 -2.08  1.05 -3.47  0.61  0.17  0.20 
C | -2.20  0.61 -0.81 -2.89 -2.89 -2.89  0.75 -1.79  1.20 -2.89  1.12 -2.89 -1.28 -2.20 -2.89  1.68  0.00 -2.89  0.51 
G |  0.92  0.58  1.33 -2.89  1.68  0.11 -1.50 -2.89 -2.89  0.77 -0.18  0.87  1.12 -2.20 -0.94 -2.89 -0.59 -2.89 -2.89 
T | -3.47 -1.86 -0.63 -3.47 -3.47  0.89 -0.69 -0.25 -3.47  0.47 -0.06 -3.47  0.09  1.06 -3.47 -3.47 -0.90  0.63 -0.06 
UME1_BFoat et. al.P = 0.0002832View matrix ↘
Sequence logo for UME1_B
Fisher’s P-value0.0002832
Information content12.36
Max PWM score11.48
Recommended cutoff11.21
Position frequency matrix (PFM)
A | 0.10 0.81 0.48 0.01 0.01 0.01 0.01 0.01 0.16 0.45 
C | 0.23 0.01 0.07 0.97 0.91 0.01 0.97 0.58 0.44 0.01 
G | 0.15 0.01 0.44 0.01 0.01 0.97 0.01 0.01 0.37 0.28 
T | 0.53 0.17 0.01 0.01 0.07 0.01 0.01 0.41 0.02 0.26 
Position count matrix (PCM)
A |  10  81  48   1   1   1   1   1  16  45 
C |  23   1   7  97  91   1  97  57  44   1 
G |  15   1  44   1   1  97   1   1  37  28 
T |  53  17   1   1   7   1   1  41   2  26 
Position weight matrix (PWM)
A | -1.16  0.93  0.41 -3.47 -3.47 -3.47 -3.47 -3.47 -0.69  0.34 
C |  0.25 -2.89 -0.94  1.68  1.62 -2.89  1.68  1.17  0.89 -2.89 
G | -0.18 -2.89  0.89 -2.89 -2.89  1.68 -2.89 -2.89  0.72  0.44 
T |  0.50 -0.63 -3.47 -3.47 -1.52 -3.47 -3.47  0.25 -2.77 -0.21 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 1 genes

No Data

Genes affected by TF deletion 173 genes

YBR006W, YGL169W, YGL232W, YGR278W, YMR010W, YML114C, YAL068C, YGR095C, YHR146W, YJL115W, YKL043W, YNL275W, YOR071C, YPL021W, YDR207C, YPR157W, YMR042W, YNR058W, YPL206C, YPL240C, YBR222C, YLR026C, YMR191W, YNL240C, YPL016W, YPR138C, YDL171C, YGR001C, YHR053C, YHR055C, YOL136C, YGL077C, YLR154C, YMR314W, YNL333W, YNL335W, YBR093C, YOL109W, YLR183C, YML022W, YNL334C, YOR160W, YOR132W, YIL090W, YOR261C, YPL182C, YGL019W, YLR033W, YLR438C-A, YLR412W, YOR075W, YGR116W, YDR071C, YHL017W, YIL117C, YJR025C, YJR094C, YNR066C, YPL186C, YDL135C, YEL020C, YFR041C, YJL124C, YOR074C, YOR386W, YGL153W, YMR113W, YOL118C, YOR357C, YJL223C, YLR192C, YMR260C, YMR294W-A, YNR035C, YPL156C, YBR101C, YFL016C, YGR012W, YIR010W, YJR150C, YMR144W, YOL117W, YOL149W, YOR298C-A, YCL027W, YGR219W, YGR253C, YER060W, YLR232W, YNL095C, YNL065W, YOL002C, YDR232W, YGL055W, YHR132W-A, YLR040C, YLR042C, YLR416C, YMR204C, YMR236W, YMR180C, YNL289W, YOR049C, YPL066W, YPR098C, YBL098W, YLR231C, YNL031C, YNL064C, YNL100W, YNR074C, YDR209C, YHR163W, YLR041W, YBR082C, YDR146C, YDR541C, YKL001C, YMR147W, YMR151W, YOL152W, YOL122C, YOR367W, YCL038C, YGR260W, YIL062C, YJR005W, YJL167W, YMR272C, YBR083W, YDR145W, YDR481C, YGR078C, YKL218C, YNR044W, YBL107C, YDR088C, YLR297W, YMR035W, YDR214W, YHR200W, YOR027W, YOR059C, YOR091W, YGL255W, YIL165C, YMR034C, YOL038W, YBR244W, YGR177C, YLR047C, YLR049C, YML018C, YMR181C, YMR243C, YPL040C, YCL004W, YDR492W, YIL044C, YLR174W, YPL134C, YJL046W, YMR098C, YOL161C, YOL101C, YOR342C, YLR173W, YML075C, YML107C, YNL007C, YNL013C, YPL139C, YPR180W