← All factors / TF RECORD

UGA3

YDL170W

View at SGD ↗

Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Morozov et. al.
Fisher’s P-value5.53e-05
Information content8.541
Max PWM score11.41
Recommended cutoff8.17
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.042 0.200 0.055 0.408 0.743 0.584 0.106 0.335 0.030 0.042 
C | 0.704 0.709 0.150 0.071 0.058 0.104 0.327 0.519 0.020 0.050 
G | 0.082 0.037 0.583 0.467 0.150 0.234 0.469 0.033 0.833 0.861 
T | 0.172 0.054 0.213 0.054 0.049 0.078 0.098 0.114 0.117 0.047 
Position count matrix (PCM)
A |   4  20   5  40  74  58  10  33   3   4 
C |  70  70  15   7   5  10  32  51   2   5 
G |   8   3  58  46  15  23  46   3  83  86 
T |  17   5  21   5   4   7   9  11  11   4 
Position weight matrix (PWM)
A | -2.03 -0.47 -1.76  0.24  0.84  0.60 -1.10  0.05 -2.37 -2.03 
C |  1.36  1.37 -0.18 -0.93 -1.13 -0.55  0.60  1.06 -2.20 -1.28 
G | -0.79 -1.58  1.18  0.95 -0.18  0.26  0.96 -1.70  1.53  1.57 
T | -0.62 -1.78 -0.41 -1.78 -1.88 -1.41 -1.18 -1.03 -1.01 -1.92 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 6

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

UGA3Badis et. al.P = 0.6999View matrix ↘
Sequence logo for UGA3
Fisher’s P-value0.6999
Information content12.23
Max PWM score10.3
Recommended cutoff5.15
Position frequency matrix (PFM)
A | 0.04 0.01 0.01 0.01 0.01 0.02 0.86 
C | 0.29 0.01 0.97 0.01 0.01 0.27 0.02 
G | 0.63 0.97 0.01 0.97 0.97 0.69 0.02 
T | 0.04 0.01 0.01 0.01 0.01 0.02 0.10 
Position count matrix (PCM)
A |   4   1   1   1   1   2  86 
C |  28   1  97   1   1  27   2 
G |  63  97   1  97  97  69   2 
T |   4   1   1   1   1   2  10 
Position weight matrix (PWM)
A | -2.08 -3.47 -3.47 -3.47 -3.47 -2.77  0.99 
C |  0.48 -2.89  1.68 -2.89 -2.89  0.41 -2.20 
G |  1.25  1.68 -2.89  1.68  1.68  1.34 -2.20 
T | -2.08 -3.47 -3.47 -3.47 -3.47 -2.77 -1.16 
UGA3_AFoat et. al.P = 1View matrix ↘
Sequence logo for UGA3_A
Fisher’s P-value1
Information content20.43
Max PWM score23.55
Recommended cutoff17.66
Position frequency matrix (PFM)
A | 0.48 0.37 0.01 0.03 0.59 0.01 0.39 0.31 0.46 0.13 0.28 0.24 0.29 0.51 0.14 0.12 0.01 0.01 0.72 0.04 0.05 0.97 0.01 0.39 0.60 0.25 
C | 0.12 0.40 0.54 0.79 0.08 0.96 0.01 0.22 0.25 0.12 0.34 0.19 0.21 0.04 0.63 0.38 0.73 0.38 0.16 0.11 0.93 0.01 0.93 0.01 0.34 0.01 
G | 0.38 0.23 0.01 0.01 0.01 0.01 0.23 0.21 0.28 0.05 0.07 0.56 0.33 0.14 0.12 0.01 0.26 0.15 0.01 0.60 0.01 0.01 0.05 0.02 0.01 0.02 
T | 0.02 0.01 0.45 0.17 0.32 0.02 0.37 0.27 0.01 0.71 0.30 0.01 0.18 0.30 0.11 0.50 0.01 0.46 0.11 0.26 0.01 0.01 0.01 0.58 0.06 0.73 
Position count matrix (PCM)
A |  48  37   1   3  59   1  39  31  46  13  28  24  28  51  14  12   1   1  72   4   5  97   1  39  60  25 
C |  12  40  54  79   8  96   1  22  25  12  34  19  21   4  63  38  73  38  16  11  93   1  93   1  34   1 
G |  38  23   1   1   1   1  23  21  28   5   7  56  33  14  12   1  26  15   1  60   1   1   5   2   1   2 
T |   2   1  45  17  32   2  37  27   1  71  30   1  18  30  11  50   1  46  11  26   1   1   1  57   6  73 
Position weight matrix (PWM)
A |  0.41  0.15 -3.47 -2.37  0.61 -3.47  0.20 -0.03  0.36 -0.90 -0.13 -0.29 -0.10  0.47 -0.83 -0.98 -3.47 -3.47  0.81 -2.08 -1.86  1.11 -3.47  0.20  0.63 -0.25 
C | -0.41  0.80  1.10  1.48 -0.81  1.67 -2.89  0.20  0.33 -0.41  0.64  0.05  0.15 -1.50  1.25  0.75  1.40  0.75 -0.12 -0.49  1.64 -2.89  1.64 -2.89  0.64 -2.89 
G |  0.75  0.25 -2.89 -2.89 -2.89 -2.89  0.25  0.15  0.44 -1.28 -0.94  1.13  0.61 -0.25 -0.41 -2.89  0.37 -0.18 -2.89  1.20 -2.89 -2.89 -1.28 -2.20 -2.89 -2.20 
T | -2.77 -3.47  0.34 -0.63  0.00 -2.77  0.15 -0.17 -3.47  0.80 -0.06 -3.47 -0.58 -0.06 -1.07  0.45 -3.47  0.36 -1.07 -0.21 -3.47 -3.47 -3.47  0.59 -1.67  0.82 
UGA3_BFoat et. al.P = 9.53e-07View matrix ↘
Sequence logo for UGA3_B
Fisher’s P-value9.53e-07
Information content16.53
Max PWM score16.95
Recommended cutoff9.32
Position frequency matrix (PFM)
A | 0.04 0.71 0.49 0.05 0.01 0.35 0.01 0.10 0.11 0.01 0.43 0.46 0.03 0.21 0.37 0.01 
C | 0.01 0.04 0.02 0.01 0.97 0.10 0.04 0.01 0.56 0.04 0.22 0.09 0.01 0.57 0.05 0.79 
G | 0.86 0.22 0.45 0.01 0.01 0.55 0.01 0.73 0.31 0.35 0.01 0.01 0.95 0.01 0.01 0.01 
T | 0.09 0.02 0.04 0.93 0.01 0.01 0.94 0.16 0.01 0.60 0.35 0.45 0.01 0.22 0.57 0.19 
Position count matrix (PCM)
A |   4  71  49   5   1  35   1  10  11   1  43  46   3  21  37   1 
C |   1   4   2   1  97  10   4   1  56   4  22   9   1  56   5  79 
G |  86  22  45   1   1  55   1  73  31  35   1   1  95   1   1   1 
T |   9   2   4  93   1   1  94  16   1  60  35  45   1  22  56  19 
Position weight matrix (PWM)
A | -2.08  0.80  0.43 -1.86 -3.47  0.09 -3.47 -1.16 -1.07 -3.47  0.30  0.36 -2.37 -0.42  0.15 -3.47 
C | -2.89 -1.50 -2.20 -2.89  1.68 -0.59 -1.50 -2.89  1.13 -1.50  0.20 -0.69 -2.89  1.15 -1.28  1.48 
G |  1.56  0.20  0.92 -2.89 -2.89  1.12 -2.89  1.40  0.54  0.66 -2.89 -2.89  1.66 -2.89 -2.89 -2.89 
T | -1.27 -2.77 -2.08  1.07 -3.47 -3.47  1.08 -0.69 -3.47  0.63  0.09  0.34 -3.47 -0.37  0.58 -0.52 
UGA3_CFoat et. al.P = 0.01531View matrix ↘
Sequence logo for UGA3_C
Fisher’s P-value0.01531
Information content17.3
Max PWM score16.4
Recommended cutoff8.3
Position frequency matrix (PFM)
A | 0.86 0.19 0.68 0.94 0.01 0.01 0.37 0.01 0.01 0.02 0.01 0.20 0.24 0.97 0.01 
C | 0.12 0.39 0.31 0.01 0.01 0.20 0.01 0.01 0.09 0.01 0.07 0.01 0.06 0.01 0.06 
G | 0.01 0.39 0.01 0.04 0.01 0.79 0.61 0.01 0.19 0.09 0.92 0.78 0.01 0.01 0.54 
T | 0.01 0.03 0.01 0.01 0.97 0.01 0.01 0.97 0.71 0.88 0.01 0.01 0.69 0.01 0.39 
Position count matrix (PCM)
A |  86  19  68  94   1   1  37   1   1   2   1  20  24  97   1 
C |  12  39  31   1   1  20   1   1   9   1   7   1   6   1   6 
G |   1  39   1   4   1  79  61   1  19   9  92  78   1   1  54 
T |   1   3   1   1  97   1   1  97  71  88   1   1  69   1  39 
Position weight matrix (PWM)
A |  0.99 -0.52  0.75  1.08 -3.47 -3.47  0.15 -3.47 -3.47 -2.77 -3.47 -0.47 -0.29  1.11 -3.47 
C | -0.41  0.77  0.54 -2.89 -2.89  0.11 -2.89 -2.89 -0.69 -2.89 -0.94 -2.89 -1.10 -2.89 -1.10 
G | -2.89  0.77 -2.89 -1.50 -2.89  1.48  1.22 -2.89  0.05 -0.69  1.63  1.47 -2.89 -2.89  1.10 
T | -3.47 -2.37 -3.47 -3.47  1.11 -3.47 -3.47  1.11  0.80  1.01 -3.47 -3.47  0.77 -3.47  0.20 
UGA3Harbison et. al.P = 0.3436View matrix ↘
Sequence logo for UGA3
Fisher’s P-value0.3436
Information content13.28
Max PWM score11.4
Recommended cutoff9.66
Position frequency matrix (PFM)
A | 0.012 0.012 0.012 0.250 0.250 0.250 0.250 0.012 0.012 0.012 
C | 0.964 0.964 0.012 0.250 0.250 0.250 0.250 0.964 0.012 0.012 
G | 0.012 0.012 0.964 0.250 0.250 0.250 0.250 0.012 0.964 0.964 
T | 0.012 0.012 0.012 0.250 0.250 0.250 0.250 0.012 0.012 0.012 
Position count matrix (PCM)
A |   1   1   1  25  25  25  25   1   1   1 
C |  96  96   1  25  25  25  25  96   1   1 
G |   1   1  96  25  25  25  25   1  96  96 
T |   1   1   1  25  25  25  25   1   1   1 
Position weight matrix (PWM)
A | -3.28 -3.28 -3.28 -0.25 -0.25 -0.25 -0.25 -3.28 -3.28 -3.28 
C |  1.68  1.68 -2.71  0.33  0.33  0.33  0.33  1.68 -2.71 -2.71 
G | -2.71 -2.71  1.68  0.33  0.33  0.33  0.33 -2.71  1.68  1.68 
T | -3.28 -3.28 -3.28 -0.25 -0.25 -0.25 -0.25 -3.28 -3.28 -3.28 
UGA3Macisaac et. alP = 0.3436View matrix ↘
Sequence logo for UGA3
Fisher’s P-value0.3436
Information content13.28
Max PWM score11.4
Recommended cutoff9.66
Position frequency matrix (PFM)
A | 0.012 0.012 0.012 0.250 0.250 0.250 0.250 0.012 0.012 0.012 
C | 0.964 0.964 0.012 0.250 0.250 0.250 0.250 0.964 0.012 0.012 
G | 0.012 0.012 0.964 0.250 0.250 0.250 0.250 0.012 0.964 0.964 
T | 0.012 0.012 0.012 0.250 0.250 0.250 0.250 0.012 0.012 0.012 
Position count matrix (PCM)
A |   1   1   1  25  25  25  25   1   1   1 
C |  96  96   1  25  25  25  25  96   1   1 
G |   1   1  96  25  25  25  25   1  96  96 
T |   1   1   1  25  25  25  25   1   1   1 
Position weight matrix (PWM)
A | -3.28 -3.28 -3.28 -0.25 -0.25 -0.25 -0.25 -3.28 -3.28 -3.28 
C |  1.68  1.68 -2.71  0.33  0.33  0.33  0.33  1.68 -2.71 -2.71 
G | -2.71 -2.71  1.68  0.33  0.33  0.33  0.33 -2.71  1.68  1.68 
T | -3.28 -3.28 -3.28 -0.25 -0.25 -0.25 -0.25 -3.28 -3.28 -3.28 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 53 genes

YAL017W, YAL018C, YAL049C, YBL106C, YBR102C, YBR103W, YDL092W, YDL094C, YDL132W, YDL154W, YDL189W, YDL190C, YDL206W, YDR159W, YDR177W, YDR394W, YER105C, YER106W, YFL002W-A, YFL002W-B, YFR023W, YFR057W, YGL083W, YGL084C, YGL115W, YGL227W, YGR017W, YGR188C, YHR016C, YHR017W, YHR123W, YHR164C, YJR083C, YJR084W, YKL078W, YKL080W, YKR102W, YLR273C, YLR274W, YML124C, YMR135W-A, YNL105W, YNL225C, YOL076W, YOL077C, YOR102W, YOR128C, YOR190W, YPL039W, YPL040C, YPL116W, YPL117C, YPL258C

Genes affected by TF deletion 81 genes

YNL275W, YOR377W, YBR005W, YCR009C, YGL166W, YMR009W, YOL014W, YOL016C, YOR220W, YOR226C, YGR120C, YMR189W, YHR053C, YMR316W, YBR093C, YOL139C, YOL109W, YBL026W, YBR288C, YDR281C, YBR010W, YLR284C, YLR257W, YOR385W, YIL117C, YOR202W, YBR166C, YDL135C, YDL075W, YGR161C, YJL124C, YLR097C, YOR327C, YDL170W, YHR215W, YLR194C, YPL156C, YBR101C, YMR112C, YMR142C, YOL149W, YOR298C-A, YPL273W, YAR071W, YBL028C, YDL201W, YER035W, YGL148W, YGR253C, YKL214C, YML063W, YML094W, YML095C-A, YMR321C, YPL117C, YDR210W, YGR136W, YGR142W, YLR292C, YLR294C, YNL031C, YNL096C, YOL032W, YBR174C, YDR209C, YGR135W, YGR137W, YKL120W, YOR052C, YGR019W, YKL001C, YIL066C, YLR172C, YDR481C, YDL241W, YER100W, YGR195W, YLR167W, YPL129W, YBR244W, YNL007C

Genes supported by both experiments 1 genes

YPL117C

Predicted TF–TF partners 3 genes

GIS1, MSN4, RGM1

Explore 3 original interaction plots →