S.ScerTFYeast transcription factor database Aaron Spivak
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TOS8

YGL096W

View at SGD ↗

Homeodomain-containing protein and putative transcription factor found associated with chromatin; target of SBF transcription factor; induced during meiosis and under cell-damaging conditions; similar to Cup9p transcription factor

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Badis et. al.
Fisher’s P-value0.3927
Information content8.592
Max PWM score7.21
Recommended cutoff4.52
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.01 0.01 0.01 0.01 0.97 0.64 
C | 0.16 0.01 0.01 0.97 0.01 0.07 
G | 0.01 0.97 0.01 0.01 0.01 0.07 
T | 0.82 0.01 0.97 0.01 0.01 0.22
Position count matrix (PCM)
A |   1   1   1   1  97  64 
C |  16   1   1  97   1   7 
G |   1  97   1   1   1   7 
T |  82   1  97   1   1  22
Position weight matrix (PWM)
A | -3.47 -3.47 -3.47 -3.47  1.11  0.69 
C | -0.12 -2.89 -2.89  1.68 -2.89 -0.94 
G | -2.89  1.68 -2.89 -2.89 -2.89 -0.94 
T |  0.94 -3.47  1.11 -3.47 -3.47 -0.37
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 1

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

TOS8Foat et. al.P = 1View matrix ↘
Sequence logo for TOS8
Fisher’s P-value1
Information content13.19
Max PWM score13.95
Recommended cutoff10.46
Position frequency matrix (PFM)
A | 0.97 0.07 0.21 0.21 0.94 0.01 0.30 0.41 0.77 0.02 0.35 0.37 0.40 
C | 0.01 0.31 0.01 0.77 0.01 0.97 0.39 0.58 0.05 0.84 0.01 0.16 0.55 
G | 0.01 0.01 0.42 0.01 0.01 0.01 0.01 0.01 0.12 0.09 0.64 0.01 0.01 
T | 0.01 0.61 0.37 0.01 0.04 0.01 0.31 0.01 0.06 0.04 0.01 0.47 0.05
Position count matrix (PCM)
A |  97   7  21  21  94   1  30  41  77   2  35  37  40 
C |   1  31   1  77   1  97  39  57   5  84   1  16  55 
G |   1   1  42   1   1   1   1   1  12   9  64   1   1 
T |   1  61  37   1   4   1  31   1   6   4   1  47   5
Position weight matrix (PWM)
A |  1.11 -1.52 -0.42 -0.42  1.08 -3.47 -0.06  0.25  0.88 -2.77  0.09  0.15  0.22 
C | -2.89  0.54 -2.89  1.45 -2.89  1.68  0.77  1.17 -1.28  1.54 -2.89 -0.12  1.12 
G | -2.89 -2.89  0.85 -2.89 -2.89 -2.89 -2.89 -2.89 -0.41 -0.69  1.27 -2.89 -2.89 
T | -3.47  0.65  0.15 -3.47 -2.08 -3.47 -0.03 -3.47 -1.67 -2.08 -3.47  0.38 -1.86
Foat et. al.
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 49 genes

YAL053W, YAL054C, YBL027W, YBL028C, YBL109W, YBL111C, YBL112C, YBL113C, YBR050C, YBR127C, YDL082W, YDL083C, YDR252W, YDR543C, YDR544C, YDR545W, YER189W, YER190W, YGR296W, YHR091C, YHR193C, YHR194W, YIL018W, YJL005W, YJR065C, YJR066W, YJR116W, YJR123W, YKL049C, YLL065W, YLR143W, YLR207W, YLR463C, YLR465C, YLR467W, YNL045W, YNL069C, YNL239W, YNL240C, YNR029C, YNR030W, YNR037C, YNR038W, YOR313C, YOR314W, YOR318C, YOR319W, YPR131C, YPR132W

Genes affected by TF deletion 25 genes

YDL100C, YDR222W, YHR146W, YPL014W, YDL037C, YDR132C, YHR085W, YLR342W, YOL136C, YBR129C, YMR104C, YLR035C, YMR023C, YMR145C, YLL067C, YNL289W, YGR139W, YBR054W, YKR032W, YLR297W, YMR034C, YBR244W, YOL101C, YGL096W, YKR003W