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TOD6

YBL054W, PBF1

View at SGD ↗

PAC motif binding protein involved in rRNA and ribosome biogenesis; subunit of the RPD3L histone deacetylase complex; Myb-like HTH transcription factor, similar to Dot6p; hypophosphorylated by rapamycin treatment in a Sch9p-dependent manne

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Zhu et. al.
Fisher’s P-value0.01306
Information content13.43
Max PWM score12.53
Recommended cutoff6.43
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.65 0.07 0.02 0.01 0.01 0.96 0.01 0.01 0.05 0.14 
C | 0.05 0.40 0.78 0.03 0.97 0.01 0.01 0.96 0.02 0.66 
G | 0.10 0.44 0.19 0.05 0.01 0.01 0.02 0.01 0.87 0.19 
T | 0.20 0.10 0.01 0.91 0.01 0.02 0.96 0.02 0.06 0.02 
Position count matrix (PCM)
A |  65   7   2   1   1  96   1   1   5  14 
C |   5  40  78   3  97   1   1  96   2  66 
G |  10  44  19   5   1   1   2   1  87  19 
T |  20  10   1  91   1   2  96   2   6   2 
Position weight matrix (PWM)
A |  0.71 -1.52 -2.77 -3.47 -3.47  1.10 -3.47 -3.47 -1.86 -0.83 
C | -1.28  0.80  1.47 -1.79  1.68 -2.89 -2.89  1.67 -2.20  1.30 
G | -0.59  0.89  0.05 -1.28 -2.89 -2.89 -2.20 -2.89  1.58  0.05 
T | -0.47 -1.16 -3.47  1.05 -3.47 -2.77  1.10 -2.77 -1.67 -2.77 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 3

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

TOD6Badis et. al.P = 0.02187View matrix ↘
Sequence logo for TOD6
Fisher’s P-value0.02187
Information content11.78
Max PWM score10.4
Recommended cutoff9.99
Position frequency matrix (PFM)
A | 0.02 0.01 0.97 0.01 0.01 0.11 0.05 0.11 
C | 0.94 0.01 0.01 0.01 0.01 0.48 0.50 0.58 
G | 0.02 0.97 0.01 0.01 0.97 0.39 0.41 0.20 
T | 0.02 0.01 0.01 0.97 0.01 0.02 0.05 0.11 
Position count matrix (PCM)
A |   2   1  97   1   1  11   5  11 
C |  94   1   1   1   1  48  50  57 
G |   2  97   1   1  97  39  41  20 
T |   2   1   1  97   1   2   5  11 
Position weight matrix (PWM)
A | -2.77 -3.47  1.11 -3.47 -3.47 -1.07 -1.86 -1.07 
C |  1.65 -2.89 -2.89 -2.89 -2.89  0.98  1.02  1.17 
G | -2.20  1.68 -2.89 -2.89  1.68  0.77  0.82  0.11 
T | -2.77 -3.47 -3.47  1.11 -3.47 -2.77 -1.86 -1.07 
TOD6Foat et. al.P = 1View matrix ↘
Sequence logo for TOD6
Fisher’s P-value1
Information content15.98
Max PWM score16.87
Recommended cutoff12.65
Position frequency matrix (PFM)
A | 0.13 0.12 0.95 0.68 0.01 0.91 0.20 0.14 0.36 0.02 0.33 0.03 0.01 0.88 0.01 0.47 0.56 
C | 0.02 0.10 0.03 0.22 0.95 0.05 0.42 0.01 0.10 0.75 0.59 0.01 0.01 0.01 0.43 0.04 0.01 
G | 0.42 0.29 0.01 0.10 0.01 0.02 0.28 0.14 0.49 0.14 0.07 0.01 0.97 0.10 0.49 0.12 0.02 
T | 0.44 0.49 0.01 0.01 0.03 0.01 0.09 0.71 0.04 0.10 0.01 0.95 0.01 0.01 0.07 0.37 0.42 
Position count matrix (PCM)
A |  13  12  95  68   1  91  20  14  36   2  33   3   1  88   1  47  56 
C |   2  10   3  22  95   5  42   1  10  75  59   1   1   1  43   4   1 
G |  42  28   1  10   1   2  28  14  49  14   7   1  97  10  49  12   2 
T |  44  49   1   1   3   1   9  71   4  10   1  95   1   1   7  37  42 
Position weight matrix (PWM)
A | -0.90 -0.98  1.09  0.75 -3.47  1.05 -0.47 -0.83  0.12 -2.77  0.03 -2.37 -3.47  1.01 -3.47  0.38  0.56 
C | -2.20 -0.59 -1.79  0.20  1.66 -1.28  0.85 -2.89 -0.59  1.43  1.19 -2.89 -2.89 -2.89  0.87 -1.50 -2.89 
G |  0.85  0.48 -2.89 -0.59 -2.89 -2.20  0.44 -0.25  1.00 -0.25 -0.94 -2.89  1.68 -0.59  1.00 -0.41 -2.20 
T |  0.32  0.43 -3.47 -3.47 -2.37 -3.47 -1.27  0.80 -2.08 -1.16 -3.47  1.09 -3.47 -3.47 -1.52  0.15  0.27 
TOD6Zhao and StormoP = 0.04576View matrix ↘
Sequence logo for TOD6
Fisher’s P-value0.04576
Information content5.186
Max PWM score5.96
Recommended cutoff4.43
Position frequency matrix (PFM)
A | 0.193 0.160 0.049 0.776 0.011 0.038 
C | 0.348 0.222 0.851 0.010 0.001 0.788 
G | 0.305 0.258 0.001 0.038 0.099 0.014 
T | 0.155 0.359 0.099 0.177 0.888 0.161 
Position count matrix (PCM)
A |  19  16   4  77   1   3 
C |  34  22  85   1   0  78 
G |  30  25   0   3   9   1 
T |  15  35   9  17  88  16 
Position weight matrix (PWM)
A | -0.51 -0.69 -1.88  0.89 -3.37 -2.13 
C |  0.66  0.21  1.55 -2.89 -5.19  1.48 
G |  0.53  0.36 -5.19 -1.56 -0.60 -2.55 
T | -0.72  0.12 -1.17 -0.59  1.02 -0.69 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 1 genes

No Data

Genes affected by TF deletion 1 genes

No Data

Genes supported by both experiments 1 genes

No Data

Predicted TF–TF partners 4 genes

DOT6, EDS1, GCR2, STB3

Explore 4 original interaction plots →