THI2
YBR240C, phoF, PHO6
Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes
Best-performing DNA-binding model.
View and copy the recommended matrices ↘
A | 0.242 0.037 0.537 0.997 0.911 0.020 0.001 0.077 0.319 0.590 0.959 0.001 0.978 0.506 0.114 0.251 C | 0.088 0.001 0.294 0.001 0.020 0.815 0.429 0.436 0.040 0.001 0.001 0.001 0.001 0.020 0.822 0.271 G | 0.508 0.961 0.001 0.001 0.001 0.031 0.037 0.365 0.001 0.001 0.020 0.997 0.020 0.473 0.020 0.001 T | 0.162 0.001 0.168 0.001 0.068 0.134 0.533 0.121 0.640 0.408 0.020 0.001 0.001 0.001 0.044 0.477
A | 24 3 53 99 91 2 0 7 31 59 95 0 97 50 11 25 C | 8 0 29 0 2 81 42 43 4 0 0 0 0 2 82 27 G | 50 96 0 0 0 3 3 36 0 0 2 99 2 47 2 0 T | 16 0 16 0 6 13 53 12 64 40 2 0 0 0 4 47
A | -0.28 -2.16 0.52 1.14 1.05 -2.77 -5.77 -1.42 -0.00 0.61 1.10 -5.77 1.12 0.46 -1.03 -0.24 C | -0.72 -5.19 0.49 -5.19 -2.20 1.51 0.87 0.88 -1.50 -5.19 -5.19 -5.19 -5.19 -2.20 1.52 0.41 G | 1.04 1.68 -5.19 -5.19 -5.19 -1.76 -1.58 0.71 -5.19 -5.19 -2.20 1.71 -2.20 0.97 -2.20 -5.19 T | -0.68 -5.77 -0.64 -5.77 -1.55 -0.87 0.51 -0.97 0.69 0.24 -2.77 -5.77 -5.77 -5.77 -1.98 0.40
Alternative candidate matrices 5
Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.
THI2_AFoat et. al.P = 8.21e-08View matrix ↘
A | 0.38 0.55 0.78 0.03 0.01 0.01 0.37 0.22 0.47 0.05 0.22 0.01 0.01 0.97 0.22 0.06 0.03 C | 0.55 0.01 0.01 0.95 0.96 0.97 0.01 0.43 0.28 0.19 0.33 0.01 0.01 0.01 0.01 0.01 0.01 G | 0.05 0.44 0.01 0.01 0.01 0.01 0.03 0.33 0.16 0.26 0.23 0.95 0.97 0.01 0.75 0.70 0.88 T | 0.02 0.01 0.20 0.01 0.02 0.01 0.59 0.02 0.09 0.50 0.22 0.03 0.01 0.01 0.02 0.23 0.08
A | 38 55 78 3 1 1 37 22 47 5 22 1 1 97 22 6 3 C | 55 1 1 95 96 97 1 43 28 19 33 1 1 1 1 1 1 G | 5 44 1 1 1 1 3 33 16 26 23 95 97 1 75 70 88 T | 2 1 20 1 2 1 59 2 9 50 22 3 1 1 2 23 8
A | 0.17 0.54 0.89 -2.37 -3.47 -3.47 0.15 -0.37 0.38 -1.86 -0.37 -3.47 -3.47 1.11 -0.37 -1.67 -2.37 C | 1.12 -2.89 -2.89 1.66 1.67 1.68 -2.89 0.87 0.44 0.05 0.61 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 G | -1.28 0.89 -2.89 -2.89 -2.89 -2.89 -1.79 0.61 -0.12 0.37 0.25 1.66 1.68 -2.89 1.43 1.36 1.59 T | -2.77 -3.47 -0.47 -3.47 -2.77 -3.47 0.61 -2.77 -1.27 0.45 -0.37 -2.37 -3.47 -3.47 -2.77 -0.33 -1.39
THI2_BFoat et. al.P = 0.0005271View matrix ↘
A | 0.35 0.01 0.52 0.01 0.01 0.04 0.31 0.34 0.12 0.07 0.28 0.02 0.33 0.01 0.01 0.97 0.11 0.81 0.03 C | 0.01 0.11 0.45 0.01 0.06 0.43 0.01 0.06 0.25 0.49 0.18 0.48 0.14 0.06 0.01 0.01 0.10 0.17 0.84 G | 0.18 0.69 0.02 0.96 0.01 0.19 0.14 0.57 0.30 0.16 0.01 0.05 0.36 0.01 0.97 0.01 0.15 0.01 0.01 T | 0.46 0.19 0.01 0.02 0.93 0.35 0.54 0.04 0.33 0.28 0.53 0.45 0.18 0.93 0.01 0.01 0.64 0.01 0.12
A | 35 1 52 1 1 4 31 34 12 7 28 2 33 1 1 97 11 81 3 C | 1 11 45 1 6 43 1 6 25 49 18 48 14 6 1 1 10 17 84 G | 18 69 2 96 1 19 14 56 30 16 1 5 36 1 97 1 15 1 1 T | 46 19 1 2 93 35 54 4 33 28 53 45 18 93 1 1 64 1 12
A | 0.09 -3.47 0.49 -3.47 -3.47 -2.08 -0.03 0.06 -0.98 -1.52 -0.13 -2.77 0.03 -3.47 -3.47 1.11 -1.07 0.93 -2.37 C | -2.89 -0.49 0.92 -2.89 -1.10 0.87 -2.89 -1.10 0.33 1.00 0.00 0.98 -0.25 -1.10 -2.89 -2.89 -0.59 -0.06 1.54 G | 0.00 1.34 -2.20 1.67 -2.89 0.05 -0.25 1.15 0.51 -0.12 -2.89 -1.28 0.69 -2.89 1.68 -2.89 -0.18 -2.89 -2.89 T | 0.36 -0.52 -3.47 -2.77 1.07 0.09 0.52 -2.08 0.03 -0.13 0.50 0.34 -0.58 1.07 -3.47 -3.47 0.69 -3.47 -0.98
THI2Harbison et. al.P = 6.81e-13View matrix ↘
A | 0.154 0.568 0.940 0.866 0.147 0.060 0.141 0.317 0.472 0.908 0.097 0.927 C | 0.034 0.203 0.049 0.033 0.645 0.339 0.441 0.005 0.014 0.048 0.020 0.061 G | 0.755 0.013 0.004 0.048 0.046 0.060 0.249 0.084 0.068 0.005 0.802 0.004 T | 0.056 0.217 0.007 0.053 0.162 0.540 0.169 0.593 0.445 0.039 0.081 0.007
A | 15 56 94 86 14 6 14 31 47 90 9 92 C | 3 20 4 3 64 33 44 0 1 4 2 6 G | 75 1 0 4 4 6 24 8 6 0 80 0 T | 5 21 0 5 16 54 16 59 44 3 8 0
A | -0.73 0.57 1.08 1.00 -0.78 -1.67 -0.82 -0.01 0.39 1.04 -1.19 1.06 C | -1.67 0.12 -1.30 -1.70 1.28 0.63 0.90 -3.58 -2.55 -1.32 -2.20 -1.08 G | 1.43 -2.63 -3.81 -1.32 -1.36 -1.10 0.32 -0.76 -0.97 -3.58 1.49 -3.81 T | -1.74 -0.39 -3.82 -1.80 -0.68 0.52 -0.64 0.62 0.33 -2.10 -1.37 -3.82
THI2Morozov et. al.P = 1View matrix ↘
A | 0.066 0.108 0.074 0.250 0.219 0.155 0.204 0.267 0.471 0.375 0.411 0.406 0.336 0.450 0.159 0.181 0.131 0.131 C | 0.878 0.076 0.058 0.300 0.167 0.291 0.311 0.496 0.198 0.265 0.188 0.298 0.276 0.148 0.359 0.613 0.569 0.046 G | 0.042 0.726 0.747 0.208 0.465 0.184 0.243 0.144 0.224 0.200 0.213 0.185 0.233 0.222 0.160 0.135 0.154 0.659 T | 0.014 0.089 0.121 0.242 0.149 0.370 0.241 0.092 0.106 0.160 0.188 0.111 0.155 0.180 0.321 0.071 0.147 0.164
A | 6 10 7 25 21 15 20 26 47 37 41 40 33 45 15 18 13 13 C | 87 7 5 30 16 29 31 49 19 26 18 29 27 14 35 61 56 4 G | 4 72 74 20 46 18 24 14 22 20 21 18 23 22 16 13 15 65 T | 1 8 12 24 14 37 24 9 10 16 18 11 15 18 32 7 14 16
A | -1.58 -1.09 -1.46 -0.25 -0.38 -0.72 -0.45 -0.18 0.39 0.16 0.25 0.24 0.05 0.34 -0.70 -0.57 -0.89 -0.89 C | 1.58 -0.86 -1.13 0.51 -0.07 0.48 0.55 1.01 0.10 0.39 0.04 0.50 0.43 -0.20 0.69 1.23 1.15 -1.36 G | -1.46 1.39 1.42 0.14 0.95 0.02 0.30 -0.22 0.22 0.11 0.17 0.03 0.26 0.21 -0.12 -0.29 -0.16 1.30 T | -3.13 -1.28 -0.97 -0.28 -0.76 0.15 -0.28 -1.25 -1.10 -0.69 -0.53 -1.06 -0.72 -0.58 0.00 -1.51 -0.78 -0.67
THI2Pachkov et alP = 3.89e-16View matrix ↘
A | 0.081 0.001 0.518 1.000 1.000 0.001 0.001 0.053 0.347 0.728 1.000 0.001 1.000 0.643 0.100 C | 0.001 0.001 0.436 0.001 0.001 0.809 0.403 0.450 0.001 0.001 0.001 0.001 0.001 0.001 0.830 G | 0.919 1.000 0.001 0.001 0.001 0.001 0.001 0.429 0.001 0.001 0.001 1.000 0.001 0.357 0.069 T | 0.001 0.001 0.046 0.001 0.001 0.191 0.597 0.068 0.653 0.272 0.001 0.001 0.001 0.001 0.001
A | 8 0 51 100 100 0 0 5 34 72 100 0 100 64 10 C | 0 0 43 0 0 80 40 45 0 0 0 0 0 0 83 G | 91 100 0 0 0 0 0 42 0 0 0 100 0 35 6 T | 0 0 4 0 0 19 59 6 65 27 0 0 0 0 0
A | -1.37 -5.77 0.48 1.14 1.14 -5.77 -5.77 -1.80 0.08 0.82 1.14 -5.77 1.14 0.70 -1.16 C | -5.19 -5.19 0.88 -5.19 -5.19 1.50 0.81 0.92 -5.19 -5.19 -5.19 -5.19 -5.19 -5.19 1.53 G | 1.63 1.71 -5.19 -5.19 -5.19 -5.19 -5.19 0.87 -5.19 -5.19 -5.19 1.71 -5.19 0.68 -0.96 T | -5.77 -5.77 -1.94 -5.77 -5.77 -0.52 0.62 -1.55 0.71 -0.16 -5.77 -5.77 -5.77 -5.77 -5.77
Gene-level annotations and interactions.
Genes bound in ChIP-chip experiments 30 genes
YBL058W, YBL059C-A, YDR179C, YDR179W-A, YDR473C, YER076C, YER138C, YER183C, YGL178W, YGL183C, YGR273C, YGR277C, YGR278W, YHR003C, YIL151C, YJL203W, YJL204C, YJR037W, YLR031W, YLR423C, YLR424W, YLR429W, YMR257C, YNL212W, YNL213C, YOL077W-A, YOL078W, YOL080C, YOL144W, YOL145C
Genes affected by TF deletion 401 genes
YBL090W, YCR012W, YCR040W, YDR432W, YER178W, YGR280C, YGR282C, YIL148W, YJR085C, YMR010W, YNL016W, YNL081C, YOR253W, YOR225W, YOR257W, YPL239W, YDL064W, YDL131W, YDR188W, YDR192C, YEL046C, YFR032C-A, YGL009C, YHR143W, YHR174W, YLR025W, YLR056W, YLR062C, YLR406C, YMR194W, YNL211C, YOR008C, YPL049C, YBR029C, YBR001C, YBR031W, YBL087C, YCR013C, YDR063W, YDR397C, YER117W, YER146W, YGR279C, YKR042W, YKR013W, YMR044W, YNL078W, YOR252W, YOR194C, YOR226C, YCR097W-A, YAL069W, YDL061C, YGR155W, YHR142W, YHR143W-A, YJL052W, YLR061W, YMR225C, YNL244C, YOR382W, YCR082W, YFR005C, YGR063C, YHR081W, YHR053C, YHR025W, YHR055C, YIR034C, YJR143C, YJR116W, YLR340W, YLR372W, YLR374C, YMR071C, YMR134W, YNL147W, YNL149C, YOR285W, YOR347C, YOR351C, YPR050C, YPR020W, YPR052C, YPL187W, YAR068W, YBL027W, YBL059W, YBR283C, YBR253W, YGL103W, YGR180C, YHR208W, YIL016W, YML085C, YMR286W, YMR256C, YNL307C, YNR032C-A, YOR103C, YPL142C, YPL144W, YBR091C, YBR067C, YDR461W, YFR006W, YGR034W, YGR064W, YHR021C, YJR146W, YJR117W, YLR339C, YMR074C, YNL110C, YNL146W, YOL077W-A, YOL109W, YOR286W, YPR013C, YPL271W, YPR051W, YAR062W, YBL026W, YBR252W, YCL018W, YDL191W, YDR281C, YER056C, YER087C-A, YGL102C, YGR211W, YGR181W, YGR215W, YIL015W, YJL178C, YLR185W, YML024W, YML055W, YML084W, YML026C, YNL302C, YNL306W, YPL143W, YBR010W, YDR378C, YER155C, YJR094W-A, YLR287C-A, YNL030W, YOR265W, YPL183W-A, YBR169C, YDL133C-A, YDL136W, YDR224C, YFR044C, YHR123W, YKL053C-A, YLR066W, YLR038C, YLR439W, YMR230W, YNL279W, YNL283C, YOR045W, YBL092W, YBR009C, YBR011C, YDR077W, YDR373W, YDR377W, YER154W, YGR285C, YNL055C, YOR234C, YPL249C-A, YJR148W, YAL012W, YAL045C, YBR162W-A, YBR196C, YDL075W, YDR225W, YJL122W, YKL081W, YLR065C, YOR078W, YBR070C, YDR502C, YGR037C, YLR344W, YLR348C, YOL144W, YOL146W, YOL086C, YOR293W, YOR327C, YOR357C, YBL003C, YGR254W, YGR192C, YKL209C, YKL178C, YMR260C, YNR037C, YPL092W, YCR088W, YDR139C, YDR471W, YFL017W-A, YHR064C, YLL010C, YLR343W, YMR138W, YMR112C, YNL150W, YNL184C, YOL143C, YPR053C, YOR221C, YBL028C, YBR262C, YGR189C, YIL027C, YJL188C, YKL177W, YLR161W, YML030W, YML094W, YML095C-A, YMR323W, YOR170W, YDR086C, YER131W, YGL189C, YHR010W, YIL158W, YIL162W, YKR057W, YKR093W, YLR262C-A, YLR234W, YLR264W, YOR239W, YPL225W, YBR171W, YHR190W, YKL058W, YLR040C, YLR104W, YLR420W, YNL285W, YNL259C, YOR393W, YPL037C, YDL058W, YCR060W, YDR447C, YHR005C-A, YHL001W, YIL127C, YJR063W, YKR092C, YLR292C, YML126C, YNL066W, YOL026C, YOR210W, YDL081C, YDL083C, YGL056C, YKL120W, YLR041W, YLR043C, YML009C, YOR020C, YOR084W, YCR097W, YDR510W, YFL026W, YHR072W-A, YKL032C, YKL003C, YLL050C, YLR388W, YOL126C, YPR062W, YDR322C-A, YDR357C, YGL087C, YGL089C, YLR170C, YBR109C, YBR145W, YDL045W-A, YDR115W, YLL014W, YLR325C, YNL190W, YNL162W, YOL121C, YPL281C, YBR268W, YJR004C, YKL216W, YKL156W, YLR167W, YMR303C, YNR044W, YNL322C, YDR056C, YDR454C, YDR396W, YDR428C, YER164W, YGL191W, YJR104C, YLR303W, YOR277C, YOR247W, YAL033W, YER019C-A, YGL031C, YGR148C, YHR136C, YHR141C, YMR245W, YPL013C, YCR028C-A, YIL133C, YKR094C, YLR237W, YLR302C, YMR003W, YNL070W, YOL040C, YOL071W, YOR276W, YOR248W, YAL030W, YBR210W, YBR244W, YGL030W, YGL032C, YGR114C, YGR118W, YJL136C, YKL069W, YLR051C, YLR421C, YPL071C, YBR118W, YBR090C, YFL034C-A, YFL037W, YGR027C, YJR135W-A, YKL006W, YKL008C, YLR332W, YOR307C, YOR369C, YPR044C, YCL007C, YCL009C, YDL182W, YDL184C, YIL008W, YJR009C, YKL164C, YLR150W, YLR180W, YLR212C, YML108W, YNR055C, YOR183W, YPL170W, YLR390W-A, YLR395C, YLR333C, YMR155W, YOL127W, YOL159C, YPR039W, YPR073C, YPR011C, YPR043W, YBL018C, YBR280C, YDL211C, YGR209C, YKL160W, YKL163W, YLR147C, YML081C-A, YOR182C, YPL165C, YPL107W, YPL171C, YIL115C, YIL173W
Genes supported by both experiments 2 genes
YOL077W-A, YOL144W
Predicted TF–TF partners 1 genes
STP1