S.ScerTFYeast transcription factor database Aaron Spivak
← All factors / TF RECORD

SUT1

YGL162W

View at SGD ↗

Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Harbison et. al.
Fisher’s P-value3.26e-21
Information content10.34
Max PWM score12.28
Recommended cutoff8.79
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.097 0.044 0.021 0.009 0.070 0.086 0.198 0.268 0.136 0.090 
C | 0.142 0.730 0.402 0.026 0.308 0.164 0.345 0.478 0.263 0.029 
G | 0.616 0.182 0.568 0.957 0.583 0.698 0.324 0.181 0.544 0.847 
T | 0.144 0.044 0.009 0.009 0.039 0.052 0.133 0.073 0.057 0.034
Position count matrix (PCM)
A |   9   4   2   0   7   8  19  26  13   9 
C |  14  73  40   2  30  16  34  47  26   2 
G |  61  18  56  95  58  69  32  18  54  84 
T |  14   4   0   0   3   5  13   7   5   3
Position weight matrix (PWM)
A | -1.19 -1.98 -2.72 -3.57 -1.52 -1.31 -0.48 -0.18 -0.86 -1.27 
C | -0.24  1.40  0.80 -1.93  0.54 -0.09  0.65  0.98  0.38 -1.83 
G |  1.23  0.01  1.15  1.67  1.18  1.36  0.59  0.01  1.11  1.55 
T | -0.80 -1.98 -3.57 -3.57 -2.10 -1.82 -0.88 -1.48 -1.73 -2.24
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 2

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

SUT1Foat et. al.P = 3.92e-20View matrix ↘
Sequence logo for SUT1
Fisher’s P-value3.92e-20
Information content14.12
Max PWM score14.58
Recommended cutoff8.42
Position frequency matrix (PFM)
A | 0.01 0.07 0.42 0.60 0.05 0.01 0.01 0.01 0.01 0.21 0.16 0.39 
C | 0.47 0.48 0.16 0.05 0.90 0.06 0.86 0.68 0.01 0.05 0.02 0.49 
G | 0.26 0.44 0.30 0.32 0.01 0.79 0.12 0.30 0.97 0.73 0.76 0.06 
T | 0.26 0.01 0.12 0.02 0.03 0.14 0.01 0.01 0.01 0.01 0.06 0.06
Position count matrix (PCM)
A |   1   7  42  60   5   1   1   1   1  21  16  39 
C |  47  48  16   5  90   6  86  68   1   5   2  49 
G |  26  44  30  32   1  79  12  30  97  73  76   6 
T |  26   1  12   2   3  14   1   1   1   1   6   6
Position weight matrix (PWM)
A | -3.47 -1.52  0.27  0.63 -1.86 -3.47 -3.47 -3.47 -3.47 -0.42 -0.69  0.20 
C |  0.96  0.98 -0.12 -1.28  1.61 -1.10  1.56  1.33 -2.89 -1.28 -2.20  1.00 
G |  0.37  0.89  0.51  0.58 -2.89  1.48 -0.41  0.51  1.68  1.40  1.44 -1.10 
T | -0.21 -3.47 -0.98 -2.77 -2.37 -0.83 -3.47 -3.47 -3.47 -3.47 -1.67 -1.67
Foat et. al.
SUT1Macisaac et. alP = 1.57e-19View matrix ↘
Sequence logo for SUT1
Fisher’s P-value1.57e-19
Information content8.108
Max PWM score9.23
Recommended cutoff6.68
Position frequency matrix (PFM)
A | 0.155 0.299 0.023 0.065 0.001 0.304 0.276 
C | 0.516 0.030 0.954 0.228 0.176 0.135 0.060 
G | 0.139 0.670 0.008 0.678 0.815 0.550 0.619 
T | 0.190 0.001 0.015 0.029 0.008 0.011 0.045
Position count matrix (PCM)
A |  15  29   2   6   0  30  27 
C |  51   3  95  22  17  13   6 
G |  13  67   0  67  81  55  61 
T |  19   0   1   2   0   1   4
Position weight matrix (PWM)
A | -0.72 -0.07 -2.63 -1.59 -5.77 -0.05 -0.15 
C |  1.05 -1.79  1.67  0.24 -0.02 -0.29 -1.10 
G | -0.26  1.31 -3.11  1.33  1.51  1.12  1.24 
T | -0.52 -5.77 -3.06 -2.40 -3.69 -3.37 -1.96
Macisaac et. al
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 172 genes

YAL053W, YAL054C, YAL063C, YAL064W, YAR050W, YAR060C, YAR061W, YBL029W, YBL041W, YBL042C, YBL043W, YBL044W, YBL045C, YBL054W, YBL055C, YBR069C, YBR158W, YBR298C, YBR299W, YCR024C, YCR096C, YDL047W, YDL214C, YDL245C, YDL246C, YDR042C, YDR077W, YDR084C, YDR098C-A, YDR098C-B, YDR133C, YDR134C, YDR194C, YDR195W, YDR220C, YDR222W, YDR343C, YDR441C, YDR442W, YEL040W, YEL069C, YER013W, YER015W, YER044C, YER045C, YER145C, YER146W, YGL001C, YGL055W, YGL056C, YGL145W, YGL146C, YGL158W, YGL162W, YGL202W, YGR035C, YGR067C, YGR069W, YGR140W, YGR218W, YGR249W, YGR271W, YGR289C, YHL027W, YHR028C, YHR049W, YHR080C, YHR081W, YHR094C, YHR095W, YHR213W, YIL012W, YIL013C, YIL099W, YIL119C, YIL122W, YIL170W, YIL171W, YIL172C, YIR020C, YJL105W, YJL191W, YJL192C, YJL194W, YJL196C, YJL216C, YJR011C, YJR127C, YJR158W, YKL062W, YKL094W, YKL096W, YKL109W, YKL110C, YKL118W, YKR009C, YKR074W, YKR075C, YKR097W, YKR102W, YLL033W, YLL034C, YLL052C, YLL053C, YLR049C, YLR083C, YLR112W, YLR153C, YLR174W, YLR235C, YLR236C, YLR237W, YLR261C, YLR262C, YLR304C, YLR311C, YLR312C, YLR312W-A, YLR339C, YLR341W, YLR413W, YML116W, YMR011W, YMR016C, YMR019W, YMR037C, YMR056C, YMR070W, YMR081C, YMR135C, YMR136W, YMR279C, YNL038W, YNL117W, YNL118C, YNL178W, YNL179C, YNL180C, YNL231C, YOL121C, YOL156W, YOL157C, YOL159C, YOR049C, YOR050C, YOR082C, YOR084W, YOR098C, YOR099W, YOR107W, YOR136W, YOR153W, YOR161C, YOR178C, YOR318C, YOR319W, YPL026C, YPL062W, YPL156C, YPL177C, YPL188W, YPL200W, YPL201C, YPL220W, YPL230W, YPR006C, YPR016C, YPR065W, YPR148C, YPR151C, YPR192W, YPR198W

Genes affected by TF deletion 57 genes

YOR065W, YMR189W, YPL016W, YLL034C, YOR317W, YML027W, YBR129C, YIR031C, YKR102W, YMR133W, YNL116W, YLR183C, YNL300W, YOR043W, YMR023C, YGR161C, YLR099C, YIR040C, YOR357C, YPR054W, YPL276W, YBR265W, YNR035C, YPL092W, YJR119C, YJR125C, YER064C, YNL312W, YIL100W, YNL065W, YLR042C, YNL289W, YDR019C, YPL222W, YOR367W, YDL242W, YNL322C, YPL127C, YPL163C, YCR069W, YHR018C, YLR297W, YOR247W, YHR200W, YPR159W, YBR244W, YLR049C, YBR152W, YFR026C, YKL035W, YLR019W, YMR276W, YHR043C, YHR073W, YJL013C, YMR155W, YGL162W

Genes supported by both experiments 4 genes

YGL162W, YKR102W, YLL034C, YLR049C

Predicted TF–TF partners 37 genes

AFT2, CRZ1, CST6, GIS1, GSM1, HAP2, HAP4, HAP5, HMS1, IME1, MBP1, MET28, MIG1, MIG2, MIG3, MSN2, MSN4, NHP10, OAF1, PDR1, PDR3, PDR8, PHD1, RGM1, RGT1, RPH1, RPN4, RSC3, RSF2, STB1, STP1, STP2, SWI4, UME6, USV1, YER130C, YER184C

Explore 37 original interaction plots →