S.ScerTFYeast transcription factor database Aaron Spivak
← All factors / TF RECORD

SUM1

YDR310C

View at SGD ↗

Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; also acts as general replication initiation factor; involved in telomere maintenance, chromatin silencing; regulated by pachytene checkpoint

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Pachkov et al
Fisher’s P-value5.24e-42
Information content13.37
Max PWM score11.35
Recommended cutoff9.62
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.392 0.004 0.001 0.428 0.001 0.920 0.003 0.479 0.989 0.972 0.527 
C | 0.052 0.488 0.001 0.008 0.988 0.018 0.518 0.119 0.009 0.020 0.046 
G | 0.557 0.001 0.999 0.008 0.010 0.060 0.459 0.009 0.002 0.003 0.052 
T | 0.001 0.509 0.001 0.556 0.002 0.002 0.020 0.392 0.001 0.005 0.374
Position count matrix (PCM)
A |  39   0   0  42   0  92   0  47  98  97  52 
C |   5  48   0   0  98   1  51  11   0   2   4 
G |  55   0  99   0   1   6  45   0   0   0   5 
T |   0  50   0  55   0   0   2  39   0   0  37
Position weight matrix (PWM)
A |  0.20 -4.38 -5.77  0.29 -5.77  1.06 -4.67  0.40  1.13  1.11  0.50 
C | -1.24  1.00 -5.19 -3.11  1.70 -2.30  1.06 -0.41 -3.00 -2.20 -1.36 
G |  1.13 -5.19  1.71 -3.11 -2.89 -1.10  0.94 -3.00 -4.50 -4.09 -1.24 
T | -5.77  0.46 -5.77  0.55 -5.08 -5.08 -2.77  0.20 -5.77 -4.16  0.16
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 6

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

SUM1Badis et. al.P = 0.0005608View matrix ↘
Sequence logo for SUM1
Fisher’s P-value0.0005608
Information content5.927
Max PWM score6.51
Recommended cutoff6.02
Position frequency matrix (PFM)
A | 0.52 0.62 0.97 0.01 0.08 0.24 0.29 0.15 
C | 0.08 0.02 0.01 0.01 0.01 0.01 0.05 0.15 
G | 0.08 0.02 0.01 0.01 0.01 0.01 0.05 0.11 
T | 0.32 0.34 0.01 0.97 0.90 0.75 0.61 0.59
Position count matrix (PCM)
A |  52  62  97   1   8  24  28  15 
C |   8   2   1   1   1   1   5  15 
G |   8   2   1   1   1   1   5  11 
T |  32  34   1  97  90  75  61  59
Position weight matrix (PWM)
A |  0.49  0.66  1.11 -3.47 -1.39 -0.29 -0.10 -0.76 
C | -0.81 -2.20 -2.89 -2.89 -2.89 -2.89 -1.28 -0.18 
G | -0.81 -2.20 -2.89 -2.89 -2.89 -2.89 -1.28 -0.49 
T |  0.00  0.06 -3.47  1.11  1.03  0.85  0.65  0.61
Badis et. al.
SUM1Foat et. al.P = 3.06e-28View matrix ↘
Sequence logo for SUM1
Fisher’s P-value3.06e-28
Information content9.665
Max PWM score9.63
Recommended cutoff8.12
Position frequency matrix (PFM)
A | 0.07 0.24 0.44 0.02 0.01 0.01 0.46 0.01 0.47 0.01 
C | 0.01 0.11 0.06 0.48 0.17 0.01 0.01 0.97 0.01 0.70 
G | 0.21 0.15 0.18 0.44 0.01 0.97 0.20 0.01 0.52 0.06 
T | 0.71 0.50 0.32 0.06 0.82 0.01 0.33 0.01 0.01 0.23
Position count matrix (PCM)
A |   7  24  44   2   1   1  46   1  47   1 
C |   1  11   6  48  17   1   1  97   1  70 
G |  21  15  18  44   1  97  20   1  52   6 
T |  71  50  32   6  82   1  33   1   1  23
Position weight matrix (PWM)
A | -1.52 -0.29  0.32 -2.77 -3.47 -3.47  0.36 -3.47  0.38 -3.47 
C | -2.89 -0.49 -1.10  0.98 -0.06 -2.89 -2.89  1.68 -2.89  1.36 
G |  0.15 -0.18  0.00  0.89 -2.89  1.68  0.11 -2.89  1.06 -1.10 
T |  0.80  0.45  0.00 -1.67  0.94 -3.47  0.03 -3.47 -3.47 -0.33
Foat et. al.
SUM1Harbison et. al.P = 4.57e-38View matrix ↘
Sequence logo for SUM1
Fisher’s P-value4.57e-38
Information content7.96
Max PWM score9.83
Recommended cutoff8.2
Position frequency matrix (PFM)
A | 0.238 0.098 0.061 0.422 0.029 0.863 0.065 0.453 0.747 0.777 0.486 
C | 0.101 0.377 0.041 0.063 0.920 0.013 0.448 0.130 0.060 0.075 0.102 
G | 0.542 0.051 0.836 0.037 0.015 0.097 0.451 0.052 0.105 0.048 0.090 
T | 0.119 0.475 0.062 0.478 0.036 0.028 0.035 0.365 0.088 0.099 0.323
Position count matrix (PCM)
A |  23   9   6  42   2  86   6  45  74  77  48 
C |  10  37   4   6  92   1  44  13   6   7  10 
G |  54   5  83   3   1   9  45   5  10   4   9 
T |  11  47   6  47   3   2   3  36   8   9  32
Position weight matrix (PWM)
A | -0.30 -1.18 -1.66  0.28 -2.40  0.99 -1.59  0.35  0.85  0.89  0.42 
C | -0.58  0.74 -1.48 -1.05  1.63 -2.63  0.91 -0.33 -1.10 -0.88 -0.57 
G |  1.10 -1.26  1.54 -1.58 -2.48 -0.62  0.92 -1.24 -0.54 -1.32 -0.69 
T | -0.99  0.39 -1.64  0.40 -2.18 -2.44 -2.21  0.13 -1.29 -1.17  0.01
Harbison et. al.
SUM1Macisaac et. alP = 2.33e-35View matrix ↘
Sequence logo for SUM1
Fisher’s P-value2.33e-35
Information content11.47
Max PWM score11.59
Recommended cutoff9.37
Position frequency matrix (PFM)
A | 0.458 0.331 0.327 0.029 0.025 0.361 0.008 0.958 0.012 0.359 0.882 0.910 0.441 0.240 
C | 0.180 0.155 0.095 0.438 0.004 0.027 0.975 0.008 0.381 0.175 0.023 0.019 0.133 0.111 
G | 0.157 0.199 0.423 0.010 0.970 0.012 0.001 0.033 0.595 0.008 0.091 0.027 0.095 0.194 
T | 0.205 0.314 0.155 0.523 0.001 0.600 0.016 0.001 0.012 0.458 0.004 0.044 0.331 0.456
Position count matrix (PCM)
A |  45  33  32   2   2  36   0  95   1  35  88  91  44  24 
C |  18  15   9  43   0   2  97   0  38  17   2   1  13  11 
G |  15  19  42   1  97   1   0   3  59   0   9   2   9  19 
T |  20  31  15  52   0  60   1   0   1  45   0   4  33  45
Position weight matrix (PWM)
A |  0.36  0.03  0.02 -2.40 -2.55  0.12 -3.69  1.10 -3.28  0.12  1.01  1.05  0.32 -0.29 
C |  0.00 -0.15 -0.64  0.89 -3.81 -1.90  1.69 -3.11  0.75 -0.03 -2.06 -2.25 -0.30 -0.48 
G | -0.14  0.10  0.85 -2.89  1.68 -2.71 -5.19 -1.70  1.20 -3.11 -0.68 -1.90 -0.64  0.07 
T | -0.45 -0.02 -0.72  0.49 -5.77  0.63 -3.00 -5.77 -3.28  0.36 -4.38 -1.98  0.03  0.35
Macisaac et. al
SUM1Zhu et. al.P = 0.0005179View matrix ↘
Sequence logo for SUM1
Fisher’s P-value0.0005179
Information content5.44
Max PWM score6.22
Recommended cutoff3.99
Position frequency matrix (PFM)
A | 0.83 0.71 0.42 0.27 0.71 0.56 0.27 0.13 
C | 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.03 
G | 0.03 0.01 0.01 0.01 0.01 0.01 0.01 0.01 
T | 0.13 0.27 0.56 0.71 0.27 0.42 0.71 0.83
Position count matrix (PCM)
A |  83  71  42  27  71  56  27  13 
C |   1   1   1   1   1   1   1   3 
G |   3   1   1   1   1   1   1   1 
T |  13  27  56  71  27  42  71  83
Position weight matrix (PWM)
A |  0.95  0.80  0.27 -0.17  0.80  0.56 -0.17 -0.90 
C | -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 -1.79 
G | -1.79 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 
T | -0.90 -0.17  0.56  0.80 -0.17  0.27  0.80  0.95
Zhu et. al.
SUM1Zhao and StormoP = 1View matrix ↘
Sequence logo for SUM1
Fisher’s P-value1
Information content2.235
Max PWM score3.4
Recommended cutoff3.31
Position frequency matrix (PFM)
A | 0.570 0.459 0.156 0.355 0.383 0.239 0.186 0.262 
C | 0.066 0.001 0.039 0.103 0.177 0.210 0.232 0.215 
G | 0.060 0.001 0.001 0.001 0.104 0.146 0.186 0.192 
T | 0.304 0.539 0.804 0.541 0.336 0.406 0.395 0.330
Position count matrix (PCM)
A |  56  45  15  35  38  23  18  26 
C |   6   0   3  10  17  21  23  21 
G |   6   0   0   0  10  14  18  19 
T |  30  53  80  54  33  40  39  33
Position weight matrix (PWM)
A |  0.58  0.36 -0.72  0.10  0.18 -0.29 -0.54 -0.20 
C | -1.00 -5.19 -1.53 -0.56 -0.02  0.15  0.25  0.18 
G | -1.10 -5.19 -5.19 -5.19 -0.55 -0.21  0.03  0.06 
T | -0.05  0.52  0.92  0.53  0.05  0.24  0.21  0.03
Zhao and Stormo
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 121 genes

YAL023C, YAL037W, YAR042W, YBR017C, YBR041W, YBR076W, YBR084W, YBR148W, YBR179C, YBR180W, YCL048W, YCL049C, YDL068W, YDL071C, YDL186W, YDL188C, YDL228C, YDR042C, YDR048C, YDR098C, YDR281C, YDR310C, YDR311W, YDR322W, YDR383C, YDR402C, YDR403W, YDR522C, YDR523C, YDR533C, YEL058W, YEL059C-A, YER105C, YER106W, YER187W, YER187W-A, YFL010W-A, YFL040W, YFR012W, YFR023W, YFR032C, YGL137W, YGL138C, YGL170C, YGR055W, YGR059W, YGR256W, YGR258C, YGR260W, YHR124W, YHR181W, YHR184W, YHR185C, YIR026C, YIR027C, YIR028W, YJL037W, YJL038C, YJL043W, YJL044C, YJR025C, YJR026W, YJR027W, YJR028W, YJR029W, YJR077C, YJR078W, YJR079W, YJR082C, YKL177W, YKL178C, YKL179C, YKR015C, YKR016W, YKR033C, YKR035W-A, YLL004W, YLL005C, YLR082C, YLR213C, YLR214W, YLR231C, YLR307W, YLR308W, YLR339C, YLR341W, YLR343W, YLR354C, YMR125W, YMR272C, YNL202W, YNL204C, YNL205C, YNL206C, YNL317W, YNL318C, YOL023W, YOL102C, YOR058C, YOR071C, YOR072W, YOR209C, YOR210W, YOR213C, YOR254C, YOR255W, YOR263C, YOR265W, YOR313C, YOR314W, YOR315W, YOR365C, YOR367W, YPL129W, YPL130W, YPL239W, YPL240C, YPL255W, YPL256C, YPL260W, YPR145W

Genes affected by TF deletion 289 genes

YCL048W, YDR368W, YGL230C, YHL012W, YGR280C, YHL048W, YLR216C, YNL052W, YNR061C, YOL047C, YNR063W, YOR255W, YEL077C, YLR463C, YOR071C, YPL019C, YBR005W, YCR013C, YER142C, YJR079W, YLR213C, YLR273C, YOL014W, YOL016C, YOR190W, YOR220W, YOR192C, YPL206C, YJR078W, YBR161W, YFR032C, YLR089C, YLR462W, YPR077C, YBR126C, YFL012W, YGR059W, YHR053C, YHR055C, YLR307W, YOL136C, YOR345C, YOR347C, YPL187W, YBR287W, YIL050W, YKL141W, YKL172W, YLR120C, YMR254C, YMR316C-A, YMR316W, YNL333W, YNL335W, YNL305C, YPL146C, YBR063C, YBR093C, YFL040W, YHR054C, YIR027C, YLR308W, YLR341W, YMR106C, YNL110C, YOL073C, YOR346W, YBR250W, YDR281C, YER085C, YGL138C, YIL051C, YKL142W, YKL206C, YMR316C-B, YNL332W, YNL334C, YNL336W, YDR042C, YGR284C, YIL124W, YJR024C, YJR060W, YMR018W, YNR071C, YDL072C, YDR230W, YER002W, YGL015C, YHR184W, YLR068W, YMR232W, YNL279W, YOR011W, YOR385W, YPL027W, YDR310C, YCL064C, YDR077W, YDR411C, YER124C, YHL021C, YJR025C, YKR015C, YMR017W, YNL055C, YNL057W, YNR064C, YOL024W, YPL214C, YPL246C, YPL218W, YBR230C, YDR223W, YHR185C, YHR126C, YKL112W, YLR099C, YMR171C, YOR072W, YOR388C, YLL005C, YLR350W, YOR298W, YPR054W, YPL276W, YCL026C-A, YHR215W, YKL178C, YLR194C, YML066C, YMR294W-A, YNR035C, YPL156C, YBR071W, YDR105C, YDR534C, YFR012W, YGR012W, YJR119C, YJR156C, YLL039C, YLR343W, YLR375W, YMR110C, YMR083W, YOL143C, YOL083W, YOR298C-A, YPL275W, YAR071W, YBL002W, YBL032W, YDR319C, YER035W, YGL084C, YGR187C, YIL053W, YKL177W, YKL150W, YML092C, YMR317W, YMR295C, YNR034W, YNL312W, YPL149W, YPL087W, YER187W-A, YIL096C, YLR232W, YNL034W, YOL058W, YBR173C, YGR136W, YKL096W, YLR040C, YLR414C, YPL033C, YBL098W, YBR045C, YGR295C, YKR088C, YLR231C, YLR233C, YLR294C, YML126C, YML130C, YML132W, YNR072W, YOL032W, YOR270C, YAL018C, YAL022C, YEL060C, YFR047C, YGR137W, YLR041W, YOR052C, YPL067C, YPR154W, YFL059W, YFR023W, YIR044C, YJL038C, YMR120C, YOL152W, YOR365C, YGR260W, YKL153W, YLR136C, YMR298W, YMR304C-A, YNL319W, YPL130W, YIR043C, YNL128W, YNL160W, YOL091W, YOR364W, YOR366W, YBR302C, YGR259C, YGR197C, YJL196C, YKL152C, YKL216W, YNL318C, YPL095C, YBL107C, YBR056W, YGL225W, YHR018C, YKR034W, YLR270W, YAR042W, YAR053W, YEL069C, YGL037C, YLR082C, YLR054C, YGL255W, YHL003C, YIL139C, YJR107W, YLR237W, YLR269C, YOR214C, YPL196W, YBR180W, YGR145W, YLR049C, YMR243C, YMR244W, YMR215W, YPL012W, YPL044C, YBR148W, YDL023C, YJL043W, YKL035W, YJR139C, YLR328W, YMR095C, YMR097C, YNL203C, YNL205C, YOL160W, YOL132W, YOR339C, YML047C, YML048W-A, YBR149W, YBR089W, YDL022W, YDR185C, YFL062W, YKL036C, YLR359W, YMR094W, YMR096W, YNL204C, YOL129W, YOL101C, YOL163W, YER073W, YER106W, YGR273C, YNL007C, YNR050C

Genes supported by both experiments 43 genes

YAR042W, YBR148W, YBR180W, YCL048W, YDR042C, YDR281C, YDR310C, YER106W, YER187W-A, YFL040W, YFR012W, YFR023W, YFR032C, YGL138C, YGR059W, YGR260W, YHR184W, YHR185C, YIR027C, YJL038C, YJL043W, YJR025C, YJR078W, YJR079W, YKL177W, YKL178C, YKR015C, YLL005C, YLR082C, YLR213C, YLR231C, YLR307W, YLR308W, YLR341W, YLR343W, YNL204C, YNL205C, YNL318C, YOR071C, YOR072W, YOR255W, YOR365C, YPL130W

Predicted TF–TF partners 5 genes

ABF1, MBP1, MET28, SKO1, STP1

Explore 5 original interaction plots →