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STB4

YMR019W

View at SGD ↗

Protein that binds Sin3p in a two-hybrid assay; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins; computational analysis suggests a role in regulation of expression of genes encoding transporters

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Pachkov et al
Fisher’s P-value4.93e-10
Information content15.45
Max PWM score12.31
Recommended cutoff11.54
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.001 0.116 0.106 0.447 0.001 0.001 0.001 0.001 0.967 
C | 0.079 0.813 0.001 0.001 0.285 1.000 1.000 0.001 0.001 
G | 0.001 0.068 0.890 0.553 0.001 0.001 0.001 1.000 0.033 
T | 0.921 0.004 0.004 0.001 0.715 0.001 0.001 0.001 0.001 
Position count matrix (PCM)
A |   0  11  10  44   0   0   0   0  96 
C |   7  81   0   0  28 100 100   0   0 
G |   0   6  89  55   0   0   0 100   3 
T |  92   0   0   0  71   0   0   0   0 
Position weight matrix (PWM)
A | -5.77 -1.01 -1.10  0.33 -5.77 -5.77 -5.77 -5.77  1.11 
C | -0.82  1.51 -5.19 -5.19  0.46  1.71  1.71 -5.19 -5.19 
G | -5.19 -0.97  1.60  1.12 -5.19 -5.19 -5.19  1.71 -1.70 
T |  1.06 -4.38 -4.38 -5.77  0.80 -5.77 -5.77 -5.77 -5.77 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 4

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

STB4Badis et. al.P = 1.01e-05View matrix ↘
Sequence logo for STB4
Fisher’s P-value1.01e-05
Information content10.61
Max PWM score8.98
Recommended cutoff7.13
Position frequency matrix (PFM)
A | 0.09 0.01 0.01 0.01 0.01 0.97 0.75 
C | 0.43 0.01 0.97 0.01 0.01 0.01 0.01 
G | 0.09 0.01 0.01 0.97 0.97 0.01 0.01 
T | 0.39 0.97 0.01 0.01 0.01 0.01 0.23 
Position count matrix (PCM)
A |   9   1   1   1   1  97  75 
C |  43   1  97   1   1   1   1 
G |   9   1   1  97  97   1   1 
T |  39  97   1   1   1   1  23 
Position weight matrix (PWM)
A | -1.27 -3.47 -3.47 -3.47 -3.47  1.11  0.85 
C |  0.87 -2.89  1.68 -2.89 -2.89 -2.89 -2.89 
G | -0.69 -2.89 -2.89  1.68  1.68 -2.89 -2.89 
T |  0.20  1.11 -3.47 -3.47 -3.47 -3.47 -0.33 
STB4Foat et. al.P = 0.02065View matrix ↘
Sequence logo for STB4
Fisher’s P-value0.02065
Information content18.88
Max PWM score20.64
Recommended cutoff10.84
Position frequency matrix (PFM)
A | 0.34 0.07 0.16 0.01 0.01 0.72 0.16 0.02 0.11 0.16 0.59 0.20 0.15 0.30 0.01 0.95 0.84 0.01 0.10 0.01 
C | 0.01 0.49 0.01 0.01 0.97 0.01 0.63 0.87 0.21 0.37 0.30 0.01 0.43 0.29 0.95 0.02 0.07 0.05 0.01 0.04 
G | 0.34 0.05 0.82 0.09 0.01 0.05 0.20 0.07 0.36 0.46 0.05 0.06 0.37 0.05 0.03 0.02 0.08 0.50 0.01 0.48 
T | 0.32 0.39 0.01 0.89 0.01 0.22 0.01 0.04 0.32 0.01 0.06 0.73 0.05 0.35 0.01 0.01 0.01 0.44 0.88 0.48 
Position count matrix (PCM)
A |  34   7  16   1   1  72  16   2  11  16  59  20  15  30   1  95  84   1  10   1 
C |   1  49   1   1  97   1  63  87  21  37  30   1  43  28  95   2   7   5   1   4 
G |  34   5  82   9   1   5  20   7  36  46   5   6  37   5   3   2   8  50   1  48 
T |  32  39   1  89   1  22   1   4  32   1   6  73   5  35   1   1   1  44  88  48 
Position weight matrix (PWM)
A |  0.06 -1.52 -0.69 -3.47 -3.47  0.81 -0.69 -2.77 -1.07 -0.69  0.61 -0.47 -0.76 -0.06 -3.47  1.09  0.97 -3.47 -1.16 -3.47 
C | -2.89  1.00 -2.89 -2.89  1.68 -2.89  1.25  1.58  0.15  0.72  0.51 -2.89  0.87  0.48  1.66 -2.20 -0.94 -1.28 -2.89 -1.50 
G |  0.64 -1.28  1.52 -0.69 -2.89 -1.28  0.11 -0.94  0.69  0.94 -1.28 -1.10  0.72 -1.28 -1.79 -2.20 -0.81  1.02 -2.89  0.98 
T |  0.00  0.20 -3.47  1.02 -3.47 -0.37 -3.47 -2.08  0.00 -3.47 -1.67  0.82 -1.86  0.09 -3.47 -3.47 -3.47  0.32  1.01  0.41 
STB4Harbison et. al.P = 1.64e-06View matrix ↘
Sequence logo for STB4
Fisher’s P-value1.64e-06
Information content11.97
Max PWM score10.2
Recommended cutoff10.04
Position frequency matrix (PFM)
A | 0.015 0.015 0.015 0.162 0.310 0.310 0.015 0.015 0.967 
C | 0.009 0.961 0.009 0.100 0.190 0.190 0.961 0.009 0.009 
G | 0.009 0.009 0.961 0.576 0.190 0.190 0.009 0.961 0.009 
T | 0.967 0.015 0.015 0.162 0.310 0.310 0.015 0.015 0.015 
Position count matrix (PCM)
A |   1   1   1  16  31  31   1   1  96 
C |   0  96   0  10  19  19  96   0   0 
G |   0   0  96  57  19  19   0  96   0 
T |  96   1   1  16  31  31   1   1   1 
Position weight matrix (PWM)
A | -3.06 -3.06 -3.06 -0.68 -0.03 -0.03 -3.06 -3.06  1.11 
C | -3.00  1.68 -3.00 -0.59  0.05  0.05  1.68 -3.00 -3.00 
G | -3.00 -3.00  1.68  1.16  0.05  0.05 -3.00  1.68 -3.00 
T |  1.11 -3.06 -3.06 -0.68 -0.03 -0.03 -3.06 -3.06 -3.06 
STB4Macisaac et. alP = 1.64e-06View matrix ↘
Sequence logo for STB4
Fisher’s P-value1.64e-06
Information content11.97
Max PWM score10.2
Recommended cutoff10.04
Position frequency matrix (PFM)
A | 0.015 0.015 0.015 0.162 0.310 0.310 0.015 0.015 0.967 
C | 0.009 0.961 0.009 0.100 0.190 0.190 0.961 0.009 0.009 
G | 0.009 0.009 0.961 0.576 0.190 0.190 0.009 0.961 0.009 
T | 0.967 0.015 0.015 0.162 0.310 0.310 0.015 0.015 0.015 
Position count matrix (PCM)
A |   1   1   1  16  31  31   1   1  96 
C |   0  96   0  10  19  19  96   0   0 
G |   0   0  96  57  19  19   0  96   0 
T |  96   1   1  16  31  31   1   1   1 
Position weight matrix (PWM)
A | -3.06 -3.06 -3.06 -0.68 -0.03 -0.03 -3.06 -3.06  1.11 
C | -3.00  1.68 -3.00 -0.59  0.05  0.05  1.68 -3.00 -3.00 
G | -3.00 -3.00  1.68  1.16  0.05  0.05 -3.00  1.68 -3.00 
T |  1.11 -3.06 -3.06 -0.68 -0.03 -0.03 -3.06 -3.06 -3.06 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 117 genes

YAL007C, YAR007C, YAR008W, YAR009C, YAR027W, YBL050W, YBL051C, YBR046C, YBR047W, YBR065C, YBR095C, YBR096W, YBR120C, YBR222C, YBR224W, YBR225W, YBR232C, YBR256C, YBR257W, YBR292C, YCR105W, YDL017W, YDL018C, YDL057W, YDL073W, YDL074C, YDR089W, YDR090C, YDR294C, YDR318W, YDR322C-A, YDR323C, YDR372C, YDR373W, YDR440W, YDR537C, YDR539W, YEL002C, YEL020C, YER066C-A, YER068W, YER138C, YER181C, YER183C, YFR041C, YFR042W, YGL137W, YGL138C, YGL156W, YGR017W, YGR094W, YGR289C, YHL038C, YHR068W, YHR084W, YIL035C, YIL048W, YIL166C, YJL003W, YJL004C, YJL023C, YJL094C, YJL193W, YJL195C, YJR098C, YJR099W, YJR154W, YKL135C, YKL202W, YKL203C, YLL055W, YLL056C, YLL057C, YLL058W, YLL059C, YLL060C, YLL061W, YLL062C, YLR199C, YLR200W, YLR273C, YLR274W, YLR330W, YML036W, YML037C, YMR031C, YMR032W, YMR034C, YMR035W, YNL082W, YNL083W, YNL084C, YNL117W, YNL118C, YNL272C, YNR011C, YNR012W, YNR054C, YOL105C, YOR058C, YOR112W, YOR115C, YOR215C, YOR297C, YOR298W, YPL076W, YPL077C, YPL215W, YPL243W, YPL244C, YPR021C, YPR082C, YPR083W, YPR107C, YPR108W, YPR128C, YPR129W

Genes affected by TF deletion 22 genes

YHR146W, YLR461W, YMR042W, YAL001C, YBR222C, YGR151C, YPL016W, YBR093C, YBR129C, YDR281C, YOR229W, YEL008W, YMR023C, YEL020C, YLR099C, YFL048C, YPL254W, YNL289W, YMR035W, YMR034C, YFR001W, YBL051C

Genes supported by both experiments 5 genes

YBL051C, YBR222C, YEL020C, YMR034C, YMR035W

Predicted TF–TF partners 3 genes

ARG81, RDS2, SUT2

Explore 3 original interaction plots →