← All factors / TF RECORD

SPT15

YER148W, TBP, TBP1, BTF1

View at SGD ↗

TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Pachkov et al
Fisher’s P-valueNo data
Information content10.14
Max PWM score9.27
Recommended cutoff6.97
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.440 0.080 0.120 0.040 0.960 0.080 1.000 0.001 0.680 0.240 0.160 
C | 0.120 0.120 0.001 0.001 0.040 0.001 0.001 0.200 0.040 0.240 0.120 
G | 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.280 0.040 0.160 
T | 0.440 0.800 0.880 0.960 0.001 0.920 0.001 0.800 0.001 0.480 0.560 
Position count matrix (PCM)
A |  44   8  12   4  96   8 100   0  68  24  16 
C |  12  12   0   0   4   0   0  20   4  24  12 
G |   0   0   0   0   0   0   0   0  28   4  16 
T |  44  80  88  96   0  92   0  80   0  48  56 
Position weight matrix (PWM)
A |  0.32 -1.39 -0.98 -2.08  1.10 -1.39  1.14 -5.77  0.75 -0.29 -0.69 
C | -0.41 -0.41 -5.19 -5.19 -1.50 -5.19 -5.19  0.11 -1.50  0.29 -0.41 
G | -5.19 -5.19 -5.19 -5.19 -5.19 -5.19 -5.19 -5.19  0.44 -1.50 -0.12 
T |  0.32  0.92  1.01  1.10 -5.77  1.06 -5.77  0.92 -5.77  0.41  0.56 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 2

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

SPT15Zhu et. al.P = No dataView matrix ↘
Sequence logo for SPT15
Fisher’s P-valueNo data
Information content10.38
Max PWM score10.51
Recommended cutoff7.88
Position frequency matrix (PFM)
A | 0.12 0.29 0.33 0.91 0.01 0.97 0.04 0.96 0.04 0.88 0.19 
C | 0.10 0.20 0.11 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.06 
G | 0.70 0.27 0.03 0.03 0.02 0.01 0.01 0.01 0.01 0.02 0.09 
T | 0.08 0.25 0.53 0.06 0.95 0.01 0.94 0.02 0.94 0.08 0.66 
Position count matrix (PCM)
A |  12  28  33  91   1  97   4  96   4  88  19 
C |  10  20  11   1   1   1   1   1   1   1   6 
G |  70  27   3   3   2   1   1   1   1   2   9 
T |   8  25  53   6  95   1  94   2  94   8  66 
Position weight matrix (PWM)
A | -0.98 -0.10  0.03  1.05 -3.47  1.11 -2.08  1.10 -2.08  1.01 -0.52 
C | -0.59  0.11 -0.49 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 -1.10 
G |  1.36  0.41 -1.79 -1.79 -2.20 -2.89 -2.89 -2.89 -2.89 -2.20 -0.69 
T | -1.39 -0.25  0.50 -1.67  1.09 -3.47  1.08 -2.77  1.08 -1.39  0.72 
SPT15Zhao and StormoP = No dataView matrix ↘
Sequence logo for SPT15
Fisher’s P-valueNo data
Information content0.413
Max PWM score1.64
Recommended cutoff1.23
Position frequency matrix (PFM)
A | 0.230 0.254 0.281 0.357 0.179 
C | 0.239 0.252 0.224 0.164 0.323 
G | 0.223 0.257 0.233 0.156 0.339 
T | 0.307 0.237 0.262 0.323 0.159 
Position count matrix (PCM)
A |  23  25  28  35  17 
C |  23  25  22  16  32 
G |  22  25  23  15  33 
T |  30  23  26  32  15 
Position weight matrix (PWM)
A | -0.33 -0.23 -0.13  0.11 -0.58 
C |  0.28  0.34  0.22 -0.09  0.58 
G |  0.21  0.36  0.26 -0.14  0.63 
T | -0.04 -0.30 -0.20  0.01 -0.70 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 1 genes

No Data

Genes affected by TF deletion 1 genes

No Data

Genes supported by both experiments 1 genes

No Data