S.ScerTFYeast transcription factor database Aaron Spivak
← All factors / TF RECORD

SMP1

YBR182C

View at SGD ↗

Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Morozov et. al.
Fisher’s P-value2.16e-07
Information content7.482
Max PWM score8.32
Recommended cutoff6.07
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.364 0.003 0.960 0.092 0.426 0.251 0.324 0.009 0.974 0.009 
C | 0.529 0.019 0.022 0.191 0.135 0.153 0.090 0.073 0.004 0.058 
G | 0.063 0.002 0.011 0.056 0.161 0.118 0.097 0.058 0.018 0.531 
T | 0.044 0.976 0.008 0.661 0.278 0.479 0.489 0.860 0.003 0.402
Position count matrix (PCM)
A |  36   0  96   9  42  25  32   0  97   0 
C |  52   1   2  19  13  15   9   7   0   5 
G |   6   0   1   5  16  11   9   5   1  53 
T |   4  97   0  66  27  47  48  86   0  40
Position weight matrix (PWM)
A |  0.13 -4.67  1.10 -1.25  0.29 -0.24  0.01 -3.57  1.11 -3.57 
C |  1.08 -2.25 -2.10  0.06 -0.29 -0.16 -0.69 -0.90 -3.81 -1.13 
G | -1.05 -4.50 -2.80 -1.17 -0.11 -0.42 -0.62 -1.13 -2.30  1.08 
T | -1.98  1.12 -3.69  0.73 -0.14  0.40  0.42  0.99 -4.67  0.23
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 6

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

SMP1Foat et. al.P = 2.81e-10View matrix ↘
Sequence logo for SMP1
Fisher’s P-value2.81e-10
Information content15.46
Max PWM score14.69
Recommended cutoff7.55
Position frequency matrix (PFM)
A | 0.40 0.03 0.73 0.05 0.97 0.58 0.05 0.01 0.74 0.01 0.52 0.01 0.26 
C | 0.22 0.50 0.01 0.92 0.01 0.22 0.67 0.94 0.17 0.97 0.01 0.04 0.73 
G | 0.36 0.01 0.26 0.01 0.01 0.19 0.01 0.01 0.09 0.01 0.43 0.01 0.01 
T | 0.01 0.46 0.01 0.02 0.01 0.01 0.28 0.04 0.01 0.01 0.04 0.94 0.01
Position count matrix (PCM)
A |  40   3  73   5  97  57   5   1  74   1  52   1  26 
C |  22  50   1  92   1  22  67  94  17  97   1   4  73 
G |  36   1  26   1   1  19   1   1   9   1  43   1   1 
T |   1  46   1   2   1   1  28   4   1   1   4  94   1
Position weight matrix (PWM)
A |  0.22 -2.37  0.82 -1.86  1.11  0.59 -1.86 -3.47  0.84 -3.47  0.49 -3.47 -0.21 
C |  0.20  1.02 -2.89  1.63 -2.89  0.20  1.31  1.65 -0.06  1.68 -2.89 -1.50  1.40 
G |  0.69 -2.89  0.37 -2.89 -2.89  0.05 -2.89 -2.89 -0.69 -2.89  0.87 -2.89 -2.89 
T | -3.47  0.36 -3.47 -2.77 -3.47 -3.47 -0.13 -2.08 -3.47 -3.47 -2.08  1.08 -3.47
Foat et. al.
SMP1Harbison et. al.P = 0.002823View matrix ↘
Sequence logo for SMP1
Fisher’s P-value0.002823
Information content18.24
Max PWM score14.42
Recommended cutoff9.46
Position frequency matrix (PFM)
A | 0.965 0.012 0.012 0.965 0.012 0.012 0.965 0.488 0.488 0.488 0.488 0.012 0.965 0.012 
C | 0.012 0.965 0.012 0.012 0.965 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 
G | 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.965 
T | 0.012 0.012 0.965 0.012 0.012 0.965 0.012 0.488 0.488 0.488 0.488 0.965 0.012 0.012
Position count matrix (PCM)
A |  96   1   1  96   1   1  96  48  48  48  48   1  96   1 
C |   1  96   1   1  96   1   1   1   1   1   1   1   1   1 
G |   1   1   1   1   1   1   1   1   1   1   1   1   1  96 
T |   1   1  96   1   1  96   1  48  48  48  48  96   1   1
Position weight matrix (PWM)
A |  1.10 -3.28 -3.28  1.10 -3.28 -3.28  1.10  0.42  0.42  0.42  0.42 -3.28  1.10 -3.28 
C | -2.71  1.68 -2.71 -2.71  1.68 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 
G | -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71  1.68 
T | -3.28 -3.28  1.10 -3.28 -3.28  1.10 -3.28  0.42  0.42  0.42  0.42  1.10 -3.28 -3.28
Harbison et. al.
SMP1Macisaac et. alP = 0.002823View matrix ↘
Sequence logo for SMP1
Fisher’s P-value0.002823
Information content18.2
Max PWM score14.42
Recommended cutoff9.46
Position frequency matrix (PFM)
A | 0.964 0.012 0.012 0.964 0.012 0.012 0.964 0.488 0.488 0.488 0.488 0.012 0.964 0.012 
C | 0.012 0.964 0.012 0.012 0.964 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 
G | 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.964 
T | 0.012 0.012 0.964 0.012 0.012 0.964 0.012 0.488 0.488 0.488 0.488 0.964 0.012 0.012
Position count matrix (PCM)
A |  96   1   1  96   1   1  96  48  48  48  48   1  96   1 
C |   1  96   1   1  96   1   1   1   1   1   1   1   1   1 
G |   1   1   1   1   1   1   1   1   1   1   1   1   1  96 
T |   1   1  96   1   1  96   1  48  48  48  48  96   1   1
Position weight matrix (PWM)
A |  1.10 -3.28 -3.28  1.10 -3.28 -3.28  1.10  0.42  0.42  0.42  0.42 -3.28  1.10 -3.28 
C | -2.71  1.68 -2.71 -2.71  1.68 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 
G | -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71 -2.71  1.68 
T | -3.28 -3.28  1.10 -3.28 -3.28  1.10 -3.28  0.42  0.42  0.42  0.42  1.10 -3.28 -3.28
Macisaac et. al
SMP1Zhu J and MQ ZhangP = 1.25e-09View matrix ↘
Sequence logo for SMP1
Fisher’s P-value1.25e-09
Information content14.24
Max PWM score17.37
Recommended cutoff9.12
Position frequency matrix (PFM)
A | 0.38 0.27 0.35 0.03 0.03 0.26 0.03 0.03 0.91 0.21 0.42 0.44 0.65 0.03 0.91 0.09 0.27 0.88 0.30 0.23 
C | 0.17 0.18 0.03 0.65 0.03 0.03 0.88 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.45 0.03 0.15 0.33 
G | 0.25 0.15 0.59 0.03 0.03 0.35 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.85 0.03 0.03 0.24 0.17 
T | 0.21 0.39 0.03 0.29 0.91 0.35 0.06 0.91 0.03 0.74 0.52 0.50 0.29 0.91 0.03 0.03 0.24 0.06 0.30 0.27
Position count matrix (PCM)
A |  38  27  35   3   3  26   3   3  91  21  42  44  65   3  91   9  27  88  30  23 
C |  17  18   3  65   3   3  88   3   3   3   3   3   3   3   3   3  45   3  15  33 
G |  25  15  59   3   3  35   3   3   3   3   3   3   3   3   3  85   3   3  24  17 
T |  21  39   3  28  91  35   6  91   3  74  52  50  28  91   3   3  24   6  30  27
Position weight matrix (PWM)
A |  0.17 -0.17  0.09 -2.37 -2.37 -0.21 -2.37 -2.37  1.05 -0.42  0.27  0.32  0.71 -2.37  1.05 -1.27 -0.17  1.01 -0.06 -0.33 
C | -0.06  0.00 -1.79  1.28 -1.79 -1.79  1.59 -1.79 -1.79 -1.79 -1.79 -1.79 -1.79 -1.79 -1.79 -1.79  0.92 -1.79 -0.18  0.61 
G |  0.33 -0.18  1.19 -1.79 -1.79  0.66 -1.79 -1.79 -1.79 -1.79 -1.79 -1.79 -1.79 -1.79 -1.79  1.55 -1.79 -1.79  0.29 -0.06 
T | -0.42  0.20 -2.37 -0.10  1.05  0.09 -1.67  1.05 -2.37  0.84  0.49  0.45 -0.10  1.05 -2.37 -2.37 -0.29 -1.67 -0.06 -0.17
Zhu J and MQ Zhang
SMP1Zhu et. al.P = 1View matrix ↘
Sequence logo for SMP1
Fisher’s P-value1
Information content6.86
Max PWM score11.39
Recommended cutoff7.01
Position frequency matrix (PFM)
A | 0.57 0.09 0.18 0.13 0.41 0.10 0.75 0.87 0.10 0.08 0.63 0.50 0.64 0.20 0.17 0.53 
C | 0.10 0.55 0.62 0.15 0.13 0.23 0.13 0.02 0.02 0.05 0.03 0.04 0.09 0.26 0.28 0.10 
G | 0.14 0.16 0.05 0.09 0.11 0.03 0.05 0.02 0.02 0.13 0.23 0.06 0.15 0.15 0.27 0.10 
T | 0.20 0.20 0.15 0.64 0.35 0.63 0.08 0.10 0.87 0.75 0.10 0.40 0.13 0.39 0.28 0.27
Position count matrix (PCM)
A |  56   9  18  13  41  10  75  87  10   8  63  50  64  20  17  53 
C |  10  55  62  15  13  23  13   2   2   5   3   4   9  26  28  10 
G |  14  16   5   9  11   3   5   2   2  13  23   6  15  15  27  10 
T |  20  20  15  64  35  63   8  10  87  75  10  40  13  39  28  27
Position weight matrix (PWM)
A |  0.58 -1.27 -0.58 -0.90  0.25 -1.16  0.85  1.00 -1.16 -1.39  0.68  0.45  0.69 -0.47 -0.63  0.50 
C | -0.59  1.12  1.24 -0.18 -0.33  0.25 -0.33 -2.20 -2.20 -1.28 -1.79 -1.50 -0.69  0.37  0.44 -0.59 
G | -0.25 -0.12 -1.28 -0.69 -0.49 -1.79 -1.28 -2.20 -2.20 -0.33  0.25 -1.10 -0.18 -0.18  0.41 -0.59 
T | -0.47 -0.47 -0.76  0.69  0.09  0.68 -1.39 -1.16  1.00  0.85 -1.16  0.22 -0.90  0.20 -0.13 -0.17
Zhu et. al.
SMP1Zhao and StormoP = 1View matrix ↘
Sequence logo for SMP1
Fisher’s P-value1
Information content2.2
Max PWM score4.09
Recommended cutoff3.6
Position frequency matrix (PFM)
A | 0.259 0.241 0.237 0.226 0.261 0.292 0.290 0.041 
C | 0.254 0.269 0.284 0.302 0.261 0.225 0.187 0.030 
G | 0.218 0.211 0.194 0.196 0.199 0.175 0.150 0.919 
T | 0.269 0.280 0.284 0.276 0.280 0.307 0.373 0.009
Position count matrix (PCM)
A |  25  24  23  22  26  29  28   4 
C |  25  26  28  30  26  22  18   3 
G |  21  21  19  19  19  17  15  91 
T |  26  28  28  27  28  30  37   0
Position weight matrix (PWM)
A | -0.21 -0.28 -0.30 -0.35 -0.20 -0.09 -0.10 -2.05 
C |  0.34  0.40  0.46  0.52  0.37  0.22  0.04 -1.79 
G |  0.19  0.16  0.07  0.09  0.10 -0.03 -0.18  1.63 
T | -0.17 -0.13 -0.12 -0.15 -0.13 -0.04  0.15 -3.57
Zhao and Stormo
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 181 genes

YAL022C, YBL001C, YBL037W, YBL087C, YBL106C, YBL109W, YBL111C, YBL112C, YBL113C, YBR057C, YBR181C, YBR182C, YBR183W, YBR188C, YBR189W, YBR190W, YBR191W, YBR298C, YBR299W, YCR073C, YDL060W, YDL061C, YDL075W, YDL076C, YDR048C, YDR309C, YDR342C, YDR350C, YDR351W, YDR366C, YDR368W, YDR418W, YDR420W, YDR500C, YDR501W, YDR543C, YDR544C, YDR545W, YEL040W, YEL054C, YER001W, YER011W, YER074W, YER132C, YFL063W, YFL064C, YFL065C, YFR031C-A, YGL030W, YGL031C, YGL077C, YGL115W, YGL134W, YGL135W, YGL136C, YGL259W, YGR117C, YGR118W, YGR143W, YGR190C, YGR282C, YGR283C, YHL027W, YHL034C, YHL041W, YHR021C, YHR021W-A, YHR030C, YHR080C, YHR081W, YHR087W, YHR091C, YHR193C, YHR194W, YHR195W, YIL015C-A, YIL122W, YIL133C, YIL174W, YIL175W, YIR013C, YIR014W, YIR020C, YIR039C, YJL039C, YJL189W, YJL190C, YJL191W, YJL192C, YJL225C, YJR044C, YJR100C, YJR158W, YKL096W, YKL163W, YKL164C, YKL180W, YKL185W, YKL186C, YKR102W, YKR105C, YKR106W, YLL065W, YLR047C, YLR048W, YLR074C, YLR075W, YLR105C, YLR287C, YLR300W, YLR332W, YLR368W, YLR387C, YLR388W, YLR389C, YLR390W, YLR390W-A, YLR392C, YLR393W, YLR394W, YLR413W, YLR463C, YLR465C, YLR467W, YML026C, YML111W, YML132W, YML133C, YMR013C, YMR014W, YMR015C, YMR165C, YMR251W-A, YNL065W, YNL066W, YNL087W, YNL097C, YNL113W, YNL115C, YNL145W, YNL236W, YNL288W, YNL302C, YNL337W, YNL338W, YNL339C, YNR050C, YOL077W-A, YOL078W, YOL080C, YOL121C, YOR134W, YOR137C, YOR138C, YOR140W, YOR236W, YOR268C, YOR269W, YOR318C, YOR319W, YOR323C, YOR325W, YOR369C, YPL018W, YPL019C, YPL050C, YPL059W, YPL060C-A, YPL090C, YPL143W, YPL175W, YPL176C, YPL192C, YPL198W, YPL251W, YPL253C, YPL257W-A, YPL257W-B, YPL283C, YPR124W, YPR198W

Genes affected by TF deletion 24 genes

YHL014C, YPL046C, YPL016W, YBR066C, YDR468C, YDL188C, YJR146W, YMR133W, YAR062W, YDR281C, YBL093C, YER089C, YKL148C, YLR234W, YIL097W, YNL197C, YKL188C, YHR136C, YMR251W, YBR053C, YBL106C, YBR023C, YMR034C, YBR182C

Genes supported by both experiments 2 genes

YBL106C, YBR182C