← All factors / TF RECORD
SIP4
YJL089W
C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
01 / RECOMMENDED MATRIX
Best-performing DNA-binding model.
Fisher’s P-value6.99e-18
Information content15.3
Max PWM score14.25
Recommended cutoff11.45
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.005 0.005 0.011 0.263 0.007 0.032 0.717 0.904 0.057 0.008 0.088 0.767 0.475 C | 0.960 0.003 0.006 0.231 0.231 0.193 0.013 0.004 0.087 0.013 0.003 0.005 0.206 G | 0.005 0.905 0.812 0.120 0.023 0.423 0.003 0.003 0.003 0.962 0.904 0.223 0.306 T | 0.030 0.087 0.171 0.386 0.739 0.352 0.267 0.089 0.853 0.017 0.005 0.005 0.014
Position count matrix (PCM)
A | 0 0 1 26 0 3 71 90 5 0 8 76 47 C | 96 0 0 23 23 19 1 0 8 1 0 0 20 G | 0 90 81 12 2 42 0 0 0 96 90 22 30 T | 3 8 17 38 73 35 26 8 85 1 0 0 1
Position weight matrix (PWM)
A | -4.16 -4.16 -3.37 -0.20 -3.82 -2.30 0.81 1.04 -1.73 -3.69 -1.29 0.87 0.39 C | 1.67 -4.09 -3.40 0.25 0.25 0.07 -2.63 -3.81 -0.73 -2.63 -4.09 -3.58 0.13 G | -3.58 1.61 1.51 -0.41 -2.06 0.85 -4.09 -4.09 -4.09 1.68 1.61 0.21 0.53 T | -2.37 -1.30 -0.63 0.19 0.84 0.10 -0.18 -1.28 0.98 -2.94 -4.16 -4.16 -3.13
02 / COMPARATIVE BENCHMARKS
Alternative candidate matrices 9
Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.
SIP4Badis et. al.P = 0.03541View matrix ↘
Fisher’s P-value0.03541
Information content9.32
Max PWM score8.66
Recommended cutoff7.35
Position frequency matrix (PFM)
A | 0.08 0.01 0.01 0.01 0.01 0.23 0.58 C | 0.48 0.26 0.97 0.97 0.01 0.01 0.16 G | 0.13 0.01 0.01 0.01 0.97 0.62 0.25 T | 0.32 0.72 0.01 0.01 0.01 0.14 0.01
Position count matrix (PCM)
A | 8 1 1 1 1 23 57 C | 48 26 97 97 1 1 16 G | 13 1 1 1 97 62 25 T | 32 72 1 1 1 14 1
Position weight matrix (PWM)
A | -1.39 -3.47 -3.47 -3.47 -3.47 -0.33 0.59 C | 0.98 0.37 1.68 1.68 -2.89 -2.89 -0.12 G | -0.33 -2.89 -2.89 -2.89 1.68 1.24 0.33 T | 0.00 0.81 -3.47 -3.47 -3.47 -0.83 -3.47
SIP4_AFoat et. al.P = 1View matrix ↘
Fisher’s P-value1
Information content17.91
Max PWM score21.1
Recommended cutoff15.82
Position frequency matrix (PFM)
A | 0.14 0.01 0.03 0.02 0.36 0.12 0.05 0.23 0.08 0.05 0.31 0.13 0.54 0.34 0.23 0.04 0.10 0.21 0.11 0.94 0.01 0.01 0.63 C | 0.23 0.01 0.01 0.04 0.12 0.25 0.07 0.37 0.29 0.31 0.22 0.08 0.20 0.01 0.68 0.32 0.19 0.50 0.86 0.01 0.01 0.36 0.01 G | 0.08 0.97 0.95 0.01 0.32 0.45 0.14 0.38 0.30 0.04 0.11 0.42 0.24 0.32 0.08 0.35 0.54 0.07 0.01 0.01 0.97 0.33 0.17 T | 0.54 0.01 0.01 0.92 0.20 0.17 0.74 0.02 0.33 0.60 0.36 0.37 0.02 0.33 0.02 0.29 0.17 0.22 0.02 0.04 0.01 0.31 0.19
Position count matrix (PCM)
A | 14 1 3 2 36 12 5 23 8 5 31 13 54 34 23 4 10 21 11 94 1 1 63 C | 23 1 1 4 12 25 7 37 28 31 22 8 20 1 68 32 19 50 86 1 1 36 1 G | 8 97 95 1 32 45 14 38 30 4 11 42 24 32 8 35 54 7 1 1 97 33 17 T | 54 1 1 92 20 17 74 2 33 60 36 37 2 33 2 28 17 22 2 4 1 31 19
Position weight matrix (PWM)
A | -0.83 -3.47 -2.37 -2.77 0.12 -0.98 -1.86 -0.33 -1.39 -1.86 -0.03 -0.90 0.52 0.06 -0.33 -2.08 -1.16 -0.42 -1.07 1.08 -3.47 -3.47 0.68 C | 0.25 -2.89 -2.89 -1.50 -0.41 0.33 -0.94 0.72 0.48 0.54 0.20 -0.81 0.11 -2.89 1.33 0.58 0.05 1.02 1.56 -2.89 -2.89 0.69 -2.89 G | -0.81 1.68 1.66 -2.89 0.58 0.92 -0.25 0.75 0.51 -1.50 -0.49 0.85 0.29 0.58 -0.81 0.66 1.10 -0.94 -2.89 -2.89 1.68 0.61 -0.06 T | 0.52 -3.47 -3.47 1.06 -0.47 -0.63 0.84 -2.77 0.03 0.63 0.12 0.15 -2.77 0.03 -2.77 -0.10 -0.63 -0.37 -2.77 -2.08 -3.47 -0.03 -0.52
SIP4_BFoat et. al.P = 1View matrix ↘
Fisher’s P-value1
Information content19.15
Max PWM score22.3
Recommended cutoff16.73
Position frequency matrix (PFM)
A | 0.26 0.50 0.01 0.01 0.97 0.10 0.14 0.32 0.08 0.47 0.53 0.32 0.07 0.40 0.16 0.29 0.10 0.26 0.05 0.01 0.01 0.01 0.33 0.16 0.49 C | 0.14 0.16 0.01 0.97 0.01 0.03 0.45 0.14 0.20 0.19 0.24 0.47 0.18 0.55 0.37 0.28 0.02 0.12 0.01 0.04 0.01 0.96 0.20 0.43 0.01 G | 0.01 0.01 0.97 0.01 0.01 0.25 0.18 0.49 0.28 0.07 0.01 0.04 0.38 0.01 0.27 0.30 0.21 0.27 0.84 0.94 0.01 0.01 0.01 0.12 0.06 T | 0.59 0.33 0.01 0.01 0.01 0.63 0.22 0.05 0.44 0.27 0.22 0.17 0.37 0.05 0.20 0.13 0.68 0.35 0.10 0.01 0.97 0.02 0.46 0.29 0.45
Position count matrix (PCM)
A | 26 50 1 1 97 10 14 32 8 47 53 32 7 40 16 28 10 26 5 1 1 1 33 16 49 C | 14 16 1 97 1 3 45 14 20 19 24 47 18 55 37 28 2 12 1 4 1 96 20 43 1 G | 1 1 97 1 1 25 18 49 28 7 1 4 38 1 27 30 21 27 84 94 1 1 1 12 6 T | 59 33 1 1 1 63 22 5 44 27 22 17 37 5 20 13 68 35 10 1 97 2 46 28 45
Position weight matrix (PWM)
A | -0.21 0.45 -3.47 -3.47 1.11 -1.16 -0.83 0.00 -1.39 0.38 0.50 0.00 -1.52 0.22 -0.69 -0.10 -1.16 -0.21 -1.86 -3.47 -3.47 -3.47 0.03 -0.69 0.43 C | -0.25 -0.12 -2.89 1.68 -2.89 -1.79 0.92 -0.25 0.11 0.05 0.29 0.96 0.00 1.12 0.72 0.44 -2.20 -0.41 -2.89 -1.50 -2.89 1.67 0.11 0.87 -2.89 G | -2.89 -2.89 1.68 -2.89 -2.89 0.33 0.00 1.00 0.44 -0.94 -2.89 -1.50 0.75 -2.89 0.41 0.51 0.15 0.41 1.54 1.65 -2.89 -2.89 -2.89 -0.41 -1.10 T | 0.61 0.03 -3.47 -3.47 -3.47 0.68 -0.37 -1.86 0.32 -0.17 -0.37 -0.63 0.15 -1.86 -0.47 -0.90 0.75 0.09 -1.16 -3.47 1.11 -2.77 0.36 -0.10 0.34
SIP4Harbison et. al.P = 1.84e-15View matrix ↘
Fisher’s P-value1.84e-15
Information content14.58
Max PWM score14.19
Recommended cutoff12.25
Position frequency matrix (PFM)
A | 0.015 0.015 0.041 0.383 0.026 0.125 0.869 0.958 0.225 0.030 0.015 0.748 0.570 C | 0.852 0.009 0.020 0.255 0.255 0.103 0.050 0.014 0.014 0.050 0.009 0.015 0.155 G | 0.015 0.960 0.923 0.149 0.088 0.359 0.009 0.009 0.009 0.858 0.960 0.223 0.222 T | 0.118 0.015 0.015 0.213 0.631 0.413 0.072 0.020 0.753 0.062 0.015 0.015 0.053
Position count matrix (PCM)
A | 1 1 4 38 2 12 86 95 22 3 1 74 56 C | 85 0 2 25 25 10 5 1 1 5 0 1 15 G | 1 96 92 14 8 35 0 0 0 85 96 22 22 T | 11 1 1 21 63 41 7 2 75 6 1 1 5
Position weight matrix (PWM)
A | -3.06 -3.06 -2.05 0.18 -2.51 -0.94 1.00 1.10 -0.35 -2.37 -3.06 0.85 0.58 C | 1.55 -3.00 -2.20 0.35 0.35 -0.56 -1.28 -2.55 -2.55 -1.28 -3.00 -2.48 -0.15 G | -2.48 1.67 1.63 -0.19 -0.72 0.69 -3.00 -3.00 -3.00 1.56 1.67 0.21 0.21 T | -1.00 -3.06 -3.06 -0.41 0.68 0.26 -1.49 -2.77 0.86 -1.64 -3.06 -3.06 -1.80
SIP4Macisaac et. alP = 4.22e-17View matrix ↘
Fisher’s P-value4.22e-17
Information content17.22
Max PWM score15.8
Recommended cutoff11.91
Position frequency matrix (PFM)
A | 0.111 0.223 0.001 0.001 0.001 0.223 0.001 0.001 0.666 0.886 0.001 0.001 0.112 0.775 0.443 C | 0.334 0.110 0.997 0.001 0.001 0.223 0.223 0.222 0.001 0.001 0.112 0.001 0.001 0.001 0.222 G | 0.222 0.001 0.001 0.887 0.775 0.111 0.001 0.445 0.001 0.001 0.001 0.997 0.886 0.223 0.334 T | 0.332 0.666 0.001 0.111 0.223 0.443 0.775 0.332 0.332 0.112 0.886 0.001 0.001 0.001 0.001
Position count matrix (PCM)
A | 11 22 0 0 0 22 0 0 66 88 0 0 11 77 44 C | 33 11 99 0 0 22 22 22 0 0 11 0 0 0 22 G | 22 0 0 88 77 11 0 44 0 0 0 99 88 22 33 T | 33 66 0 11 22 44 77 33 33 11 88 0 0 0 0
Position weight matrix (PWM)
A | -1.06 -0.36 -5.77 -5.77 -5.77 -0.36 -5.77 -5.77 0.73 1.02 -5.77 -5.77 -1.05 0.88 0.33 C | 0.62 -0.49 1.71 -5.19 -5.19 0.21 0.21 0.21 -5.19 -5.19 -0.47 -5.19 -5.19 -5.19 0.21 G | 0.21 -5.19 -5.19 1.59 1.46 -0.48 -5.19 0.91 -5.19 -5.19 -5.19 1.71 1.59 0.21 0.62 T | 0.04 0.73 -5.77 -1.06 -0.36 0.33 0.88 0.04 0.04 -1.05 1.02 -5.77 -5.77 -5.77 -5.77
SIP4Morozov et. al.P = 7.95e-14View matrix ↘
Fisher’s P-value7.95e-14
Information content11.58
Max PWM score12.39
Recommended cutoff10.29
Position frequency matrix (PFM)
A | 0.055 0.005 0.043 0.597 0.090 0.123 0.412 0.507 0.157 0.012 0.021 0.012 C | 0.280 0.931 0.697 0.038 0.069 0.135 0.269 0.073 0.170 0.946 0.914 0.030 G | 0.081 0.043 0.205 0.283 0.189 0.159 0.182 0.358 0.417 0.017 0.034 0.945 T | 0.584 0.021 0.055 0.083 0.653 0.583 0.137 0.062 0.256 0.025 0.032 0.013
Position count matrix (PCM)
A | 5 0 4 59 9 12 41 50 15 1 2 1 C | 28 93 69 3 6 13 26 7 17 94 91 3 G | 8 4 20 28 18 15 18 35 41 1 3 94 T | 58 2 5 8 65 58 13 6 25 2 3 1
Position weight matrix (PWM)
A | -1.76 -4.16 -2.01 0.62 -1.27 -0.96 0.25 0.46 -0.71 -3.28 -2.72 -3.28 C | 0.44 1.64 1.35 -1.56 -0.96 -0.29 0.40 -0.90 -0.06 1.66 1.62 -1.79 G | -0.80 -1.43 0.13 0.45 0.05 -0.12 0.01 0.69 0.84 -2.36 -1.67 1.66 T | 0.60 -2.72 -1.76 -1.35 0.71 0.60 -0.85 -1.64 -0.22 -2.55 -2.30 -3.20
SIP4Pachkov et alP = 3.79e-11View matrix ↘
Fisher’s P-value3.79e-11
Information content19.84
Max PWM score16.09
Recommended cutoff9.59
Position frequency matrix (PFM)
A | 0.001 0.001 0.023 0.664 0.001 0.122 1.000 1.000 0.483 0.001 0.001 0.842 0.349 C | 1.000 0.001 0.001 0.191 0.218 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.166 G | 0.001 1.000 0.977 0.145 0.001 0.747 0.001 0.001 0.001 0.835 1.000 0.158 0.474 T | 0.001 0.001 0.001 0.001 0.782 0.131 0.001 0.001 0.517 0.165 0.001 0.001 0.011
Position count matrix (PCM)
A | 0 0 2 66 0 12 100 100 48 0 0 84 34 C | 100 0 0 19 21 0 0 0 0 0 0 0 16 G | 0 100 97 14 0 74 0 0 0 83 100 15 47 T | 0 0 0 0 78 13 0 0 51 16 0 0 1
Position weight matrix (PWM)
A | -5.77 -5.77 -2.63 0.73 -5.77 -0.96 1.14 1.14 0.41 -5.77 -5.77 0.97 0.09 C | 1.71 -5.19 -5.19 0.06 0.19 -5.19 -5.19 -5.19 -5.19 -5.19 -5.19 -5.19 -0.08 G | -5.19 1.71 1.69 -0.22 -5.19 1.42 -5.19 -5.19 -5.19 1.53 1.71 -0.13 0.97 T | -5.77 -5.77 -5.77 -5.77 0.89 -0.89 -5.77 -5.77 0.48 -0.66 -5.77 -5.77 -3.37
SIP4Zhu et. al.P = 0.0768View matrix ↘
Fisher’s P-value0.0768
Information content11.78
Max PWM score13.34
Recommended cutoff8.28
Position frequency matrix (PFM)
A | 0.06 0.20 0.29 0.17 0.35 0.33 0.10 0.02 0.01 0.01 0.01 0.05 0.85 0.64 C | 0.51 0.38 0.30 0.34 0.26 0.16 0.21 0.08 0.92 0.93 0.05 0.01 0.05 0.05 G | 0.13 0.27 0.25 0.15 0.11 0.14 0.05 0.05 0.01 0.05 0.93 0.92 0.08 0.21 T | 0.30 0.15 0.15 0.34 0.29 0.37 0.64 0.85 0.05 0.01 0.01 0.01 0.02 0.10
Position count matrix (PCM)
A | 6 20 28 17 35 33 10 2 1 1 1 5 85 64 C | 51 38 30 34 26 16 21 8 92 93 5 1 5 5 G | 13 27 25 15 11 14 5 5 1 5 93 92 8 21 T | 30 15 15 34 28 37 64 85 5 1 1 1 2 10
Position weight matrix (PWM)
A | -1.67 -0.47 -0.10 -0.63 0.09 0.03 -1.16 -2.77 -3.47 -3.47 -3.47 -1.86 0.98 0.69 C | 1.04 0.75 0.51 0.64 0.37 -0.12 0.15 -0.81 1.63 1.64 -1.28 -2.89 -1.28 -1.28 G | -0.33 0.41 0.33 -0.18 -0.49 -0.25 -1.28 -1.28 -2.89 -1.28 1.64 1.63 -0.81 0.15 T | -0.06 -0.76 -0.76 0.06 -0.10 0.15 0.69 0.98 -1.86 -3.47 -3.47 -3.47 -2.77 -1.16
SIP4Zhao and StormoP = 1View matrix ↘
Fisher’s P-value1
Information content3.073
Max PWM score5.92
Recommended cutoff5.31
Position frequency matrix (PFM)
A | 0.277 0.204 0.171 0.086 0.899 0.239 0.274 0.390 C | 0.243 0.218 0.335 0.595 0.025 0.075 0.182 0.175 G | 0.256 0.289 0.253 0.198 0.075 0.571 0.385 0.254 T | 0.224 0.289 0.241 0.121 0.001 0.115 0.158 0.181
Position count matrix (PCM)
A | 27 20 17 8 89 23 27 39 C | 24 21 33 59 2 7 18 17 G | 25 28 25 19 7 57 38 25 T | 22 28 24 12 0 11 15 18
Position weight matrix (PWM)
A | -0.14 -0.45 -0.63 -1.31 1.03 -0.29 -0.16 0.20 C | 0.30 0.19 0.62 1.20 -1.97 -0.88 0.01 -0.03 G | 0.35 0.47 0.34 0.10 -0.88 1.15 0.76 0.34 T | -0.36 -0.10 -0.28 -0.97 -5.77 -1.02 -0.71 -0.57
03 / EXPERIMENTAL CONTEXT
Gene-level annotations and interactions.
Genes bound in ChIP-chip experiments 84 genes
YAL009W, YAL010C, YAL021C, YBR061C, YCR018C-A, YCR019W, YCR083W, YDL091C, YDL176W, YDL177C, YDR016C, YDR086C, YDR098C-A, YDR098C-B, YDR131C, YDR184C, YDR257C, YDR282C, YDR317W, YDR326C, YDR327W, YDR369C, YDR370C, YDR371W, YDR372C, YDR373W, YDR454C, YDR456W, YDR522C, YDR523C, YEL030W, YEL048C, YER023W, YFR002W, YGL001C, YGL002W, YGL003C, YGL185C, YGL192W, YGL194C, YGL230C, YGR071C, YGR072W, YGR089W, YGR104C, YGR105W, YGR188C, YHL042W, YHR155W, YIL110W, YJL111W, YJR098C, YJR099W, YJR108W, YKL077W, YKR031C, YKR032W, YKR034W, YKR061W, YLR127C, YLR128W, YML002W, YMR176W, YMR211W, YMR258C, YNL081C, YNL102W, YNL129W, YNL130C, YNL260C, YNR039C, YNR040W, YNR048W, YOL023W, YOL072W, YOL073C, YOL079W, YOL160W, YOR093C, YOR094W, YOR148C, YOR266W, YPL122C, YPL260W
Genes affected by TF deletion 34 genes
YKR071C, YHR146W, YGR151C, YHR179W, YPL016W, YLR368W, YMR314W, YBR129C, YBL058W, YER029C, YOR229W, YAR015W, YOR043W, YJR094C, YMR023C, YNR066C, YLR099C, YJR157W, YNL157W, YBR265W, YMR294W-A, YPL122C, YBR135W, YGR012W, YIR010W, YOR324C, YNL065W, YMR178W, YNL289W, YDR019C, YAL062W, YNL299W, YBR244W, YNL264C
Genes supported by both experiments 1 genes
YPL122C