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RME1

YGR044C, CSP1

View at SGD ↗

Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Macisaac et. al
Fisher’s P-value8.42e-08
Information content8.744
Max PWM score9.56
Recommended cutoff6.67
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.001 0.121 0.119 0.989 0.743 0.860 0.187 0.227 0.580 0.790 
C | 0.180 0.324 0.338 0.001 0.001 0.107 0.001 0.001 0.141 0.002 
G | 0.003 0.120 0.171 0.009 0.100 0.001 0.811 0.763 0.126 0.075 
T | 0.816 0.436 0.371 0.001 0.156 0.032 0.001 0.009 0.153 0.133 
Position count matrix (PCM)
A |   0  12  11  98  74  86  18  22  57  79 
C |  18  32  33   0   0  10   0   0  14   0 
G |   0  12  17   0  10   0  81  76  12   7 
T |  81  43  37   0  15   3   0   0  15  13 
Position weight matrix (PWM)
A | -5.77 -0.97 -0.99  1.13  0.84  0.99 -0.54 -0.34  0.59  0.90 
C |  0.00  0.59  0.63 -5.19 -5.19 -0.52 -5.19 -5.19 -0.24 -4.50 
G | -4.09 -0.41 -0.05 -3.00 -0.59 -5.19  1.51  1.44 -0.36 -0.88 
T |  0.94  0.31  0.15 -5.77 -0.72 -2.30 -5.77 -3.57 -0.74 -0.88 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 1

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

RME1Foat et. al.P = 0.0009001View matrix ↘
Sequence logo for RME1
Fisher’s P-value0.0009001
Information content19.27
Max PWM score21.35
Recommended cutoff10.88
Position frequency matrix (PFM)
A | 0.01 0.01 0.08 0.01 0.39 0.97 0.44 0.16 0.35 0.63 0.01 0.67 0.35 0.27 0.40 0.69 0.01 0.97 0.48 0.30 0.01 
C | 0.01 0.14 0.01 0.97 0.60 0.01 0.35 0.56 0.01 0.04 0.93 0.01 0.36 0.01 0.14 0.01 0.13 0.01 0.44 0.40 0.55 
G | 0.60 0.69 0.01 0.01 0.01 0.01 0.03 0.01 0.08 0.22 0.05 0.08 0.16 0.57 0.01 0.30 0.78 0.01 0.03 0.09 0.44 
T | 0.39 0.16 0.90 0.01 0.01 0.01 0.18 0.27 0.57 0.11 0.01 0.24 0.13 0.15 0.46 0.01 0.08 0.01 0.04 0.21 0.01 
Position count matrix (PCM)
A |   1   1   8   1  39  97  44  16  35  63   1  67  35  27  40  69   1  97  48  30   1 
C |   1  14   1  97  60   1  35  56   1   4  93   1  36   1  14   1  13   1  44  40  55 
G |  60  69   1   1   1   1   3   1   8  22   5   8  16  56   1  30  78   1   3   9  44 
T |  39  16  90   1   1   1  18  27  56  11   1  24  13  15  46   1   8   1   4  21   1 
Position weight matrix (PWM)
A | -3.47 -3.47 -1.39 -3.47  0.20  1.11  0.32 -0.69  0.09  0.68 -3.47  0.74  0.09 -0.17  0.22  0.77 -3.47  1.11  0.41 -0.06 -3.47 
C | -2.89 -0.25 -2.89  1.68  1.20 -2.89  0.66  1.13 -2.89 -1.50  1.64 -2.89  0.69 -2.89 -0.25 -2.89 -0.33 -2.89  0.89  0.80  1.12 
G |  1.20  1.34 -2.89 -2.89 -2.89 -2.89 -1.79 -2.89 -0.81  0.20 -1.28 -0.81 -0.12  1.15 -2.89  0.51  1.47 -2.89 -1.79 -0.69  0.89 
T |  0.20 -0.69  1.03 -3.47 -3.47 -3.47 -0.58 -0.17  0.58 -1.07 -3.47 -0.29 -0.90 -0.76  0.36 -3.47 -1.39 -3.47 -2.08 -0.42 -3.47 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 107 genes

YAL004W, YBL001C, YBL002W, YBL003C, YBL025W, YBL074C, YBR216C, YBR217W, YDL130W, YDL184C, YDR042C, YDR048C, YDR210W-D, YDR526C, YEL012W, YER078C, YER079W, YER177W, YER189W, YER190W, YFL034W, YFR017C, YGL050W, YGL134W, YGL135W, YGL136C, YGL190C, YGL234W, YGL236C, YGR030C, YGR031W, YGR060W, YGR109C, YGR109W-A, YGR109W-B, YGR256W, YHL034C, YHR143W, YIL014W, YIL015C-A, YIL050W, YIL051C, YIL052C, YIL158W, YIL161W, YIL169C, YJL045W, YJL148W, YJL188C, YJL189W, YJL190C, YJL191W, YJL192C, YJR100C, YKL042W, YKL118W, YKL132C, YKR062W, YLL063C, YLR027C, YLR029C, YLR030W, YLR061W, YLR065C, YLR066W, YLR074C, YLR075W, YLR105C, YLR367W, YLR368W, YLR369W, YLR439W, YML055W, YML056C, YML100W, YML101C, YML102C-A, YML125C, YML131W, YMR013C, YMR014W, YMR052C-A, YMR053C, YMR054W, YMR144W, YMR165C, YMR261C, YMR262W, YNL032W, YNL034W, YNL250W, YNL251C, YNR018W, YNR044W, YOL154W, YOR042W, YOR138C, YOR140W, YOR236W, YOR369C, YPL090C, YPL130W, YPL141C, YPL143W, YPL198W, YPR109W, YPR161C

Genes affected by TF deletion 39 genes

YLR216C, YOR037W, YAR068W, YMR314W, YBR093C, YBR097W, YBR129C, YIL124W, YNL281W, YGL180W, YMR017W, YER001W, YOR074C, YOL150C, YOR298W, YHR214W, YOR298C-A, YBR296C, YHR214W-A, YOR136W, YKR028W, YPL256C, YGL055W, YKR086W, YLR294C, YDR209C, YBR079C, YGR044C, YOL151W, YOL155C, YOR027W, YGL255W, YIL169C, YLR269C, YBR244W, YMR306W, YNL200C, YNL007C, YPR176C

Genes supported by both experiments 1 genes

YIL169C