← All factors / TF RECORD

RGT1

YKL038W

View at SGD ↗

Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator and repressor

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Macisaac et. al
Fisher’s P-value5.08e-06
Information content15.9
Max PWM score12.38
Recommended cutoff10.89
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.001 0.001 0.001 0.001 0.001 0.997 0.749 0.915 0.997 0.997 
C | 0.416 0.417 0.915 0.001 0.001 0.001 0.001 0.001 0.001 0.001 
G | 0.582 0.083 0.001 0.997 0.997 0.001 0.001 0.001 0.001 0.001 
T | 0.001 0.500 0.083 0.001 0.001 0.001 0.250 0.083 0.001 0.001 
Position count matrix (PCM)
A |   0   0   0   0   0  99  74  91  99  99 
C |  41  41  91   0   0   0   0   0   0   0 
G |  58   8   0  99  99   0   0   0   0   0 
T |   0  50   8   0   0   0  25   8   0   0 
Position weight matrix (PWM)
A | -5.77 -5.77 -5.77 -5.77 -5.77  1.14  0.85  1.05  1.14  1.14 
C |  0.84  0.84  1.63 -5.19 -5.19 -5.19 -5.19 -5.19 -5.19 -5.19 
G |  1.17 -0.77 -5.19  1.71  1.71 -5.19 -5.19 -5.19 -5.19 -5.19 
T | -5.77  0.45 -1.35 -5.77 -5.77 -5.77 -0.25 -1.35 -5.77 -5.77 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 7

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

RGT1Badis et. al.P = 0.006004View matrix ↘
Sequence logo for RGT1
Fisher’s P-value0.006004
Information content8.611
Max PWM score8.1
Recommended cutoff7.63
Position frequency matrix (PFM)
A | 0.36 0.22 0.27 0.30 0.01 0.01 0.01 0.04 
C | 0.01 0.02 0.15 0.18 0.12 0.97 0.97 0.01 
G | 0.01 0.01 0.17 0.04 0.01 0.01 0.01 0.87 
T | 0.62 0.75 0.41 0.48 0.86 0.01 0.01 0.08 
Position count matrix (PCM)
A |  36  22  27  30   1   1   1   4 
C |   1   2  15  18  12  97  97   1 
G |   1   1  17   4   1   1   1  87 
T |  62  75  41  48  86   1   1   8 
Position weight matrix (PWM)
A |  0.12 -0.37 -0.17 -0.06 -3.47 -3.47 -3.47 -2.08 
C | -2.89 -2.20 -0.18  0.00 -0.41  1.68  1.68 -2.89 
G | -2.89 -2.89 -0.06 -1.50 -2.89 -2.89 -2.89  1.58 
T |  0.66  0.85  0.25  0.41  0.99 -3.47 -3.47 -1.39 
RGT1_AFoat et. al.P = 0.0005686View matrix ↘
Sequence logo for RGT1_A
Fisher’s P-value0.0005686
Information content17.95
Max PWM score17.22
Recommended cutoff9.35
Position frequency matrix (PFM)
A | 0.13 0.19 0.44 0.15 0.01 0.01 0.01 0.07 0.03 0.39 0.01 0.01 0.01 0.43 0.48 
C | 0.01 0.01 0.17 0.01 0.01 0.59 0.01 0.61 0.02 0.60 0.97 0.01 0.01 0.01 0.49 
G | 0.01 0.08 0.38 0.82 0.16 0.01 0.01 0.01 0.01 0.01 0.01 0.97 0.97 0.26 0.01 
T | 0.85 0.73 0.01 0.03 0.82 0.39 0.96 0.31 0.95 0.01 0.01 0.01 0.01 0.31 0.03 
Position count matrix (PCM)
A |  13  19  44  15   1   1   1   7   3  39   1   1   1  43  48 
C |   1   1  17   1   1  59   1  61   2  60  97   1   1   1  49 
G |   1   8  38  82  16   1   1   1   1   1   1  97  97  26   1 
T |  85  73   1   3  82  39  96  31  95   1   1   1   1  31   3 
Position weight matrix (PWM)
A | -0.90 -0.52  0.32 -0.76 -3.47 -3.47 -3.47 -1.52 -2.37  0.20 -3.47 -3.47 -3.47  0.30  0.41 
C | -2.89 -2.89 -0.06 -2.89 -2.89  1.19 -2.89  1.22 -2.20  1.20  1.68 -2.89 -2.89 -2.89  1.00 
G | -2.89 -0.81  0.75  1.52 -0.12 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89  1.68  1.68  0.37 -2.89 
T |  0.98  0.82 -3.47 -2.37  0.94  0.20  1.10 -0.03  1.09 -3.47 -3.47 -3.47 -3.47 -0.03 -2.37 
RGT1_BFoat et. al.P = 0.09927View matrix ↘
Sequence logo for RGT1_B
Fisher’s P-value0.09927
Information content9.251
Max PWM score11.5
Recommended cutoff5.84
Position frequency matrix (PFM)
A | 0.25 0.22 0.45 0.01 0.58 0.01 0.35 0.44 0.22 0.01 0.91 0.01 0.13 0.17 0.03 
C | 0.31 0.31 0.30 0.35 0.01 0.01 0.43 0.02 0.33 0.13 0.01 0.11 0.07 0.53 0.55 
G | 0.01 0.14 0.09 0.01 0.01 0.01 0.01 0.15 0.01 0.01 0.01 0.01 0.27 0.01 0.23 
T | 0.44 0.33 0.16 0.63 0.41 0.97 0.22 0.38 0.44 0.85 0.07 0.87 0.53 0.30 0.19 
Position count matrix (PCM)
A |  25  22  45   1  57   1  35  44  22   1  91   1  13  17   3 
C |  31  31  30  35   1   1  43   2  33  13   1  11   7  53  55 
G |   1  14   9   1   1   1   1  15   1   1   1   1  27   1  23 
T |  44  33  16  63  41  97  22  38  44  85   7  87  53  30  19 
Position weight matrix (PWM)
A | -0.25 -0.37  0.34 -3.47  0.59 -3.47  0.09  0.32 -0.37 -3.47  1.05 -3.47 -0.90 -0.63 -2.37 
C |  0.54  0.54  0.51  0.66 -2.89 -2.89  0.87 -2.20  0.61 -0.33 -2.89 -0.49 -0.94  1.08  1.12 
G | -2.89 -0.25 -0.69 -2.89 -2.89 -2.89 -2.89 -0.18 -2.89 -2.89 -2.89 -2.89  0.41 -2.89  0.25 
T |  0.32  0.03 -0.69  0.68  0.25  1.11 -0.37  0.17  0.32  0.98 -1.52  1.00  0.50 -0.06 -0.52 
RGT1Harbison et. al.P = 0.128View matrix ↘
Sequence logo for RGT1
Fisher’s P-value0.128
Information content9.422
Max PWM score7.9
Recommended cutoff6.74
Position frequency matrix (PFM)
A | 0.012 0.012 0.012 0.965 0.250 0.250 0.965 
C | 0.965 0.012 0.012 0.012 0.250 0.250 0.012 
G | 0.012 0.965 0.965 0.012 0.250 0.250 0.012 
T | 0.012 0.012 0.012 0.012 0.250 0.250 0.012 
Position count matrix (PCM)
A |   1   1   1  96  25  25  96 
C |  96   1   1   1  25  25   1 
G |   1  96  96   1  25  25   1 
T |   1   1   1   1  25  25   1 
Position weight matrix (PWM)
A | -3.28 -3.28 -3.28  1.10 -0.25 -0.25  1.10 
C |  1.68 -2.71 -2.71 -2.71  0.33  0.33 -2.71 
G | -2.71  1.68  1.68 -2.71  0.33  0.33 -2.71 
T | -3.28 -3.28 -3.28 -3.28 -0.25 -0.25 -3.28 
RGT1Pachkov et alP = 0.05694View matrix ↘
Sequence logo for RGT1
Fisher’s P-value0.05694
Information content12.31
Max PWM score9.41
Recommended cutoff5.99
Position frequency matrix (PFM)
A | 0.001 0.001 0.030 0.001 0.001 0.001 0.039 
C | 0.001 0.033 0.061 0.064 1.000 0.970 0.001 
G | 0.031 0.001 0.001 0.001 0.001 0.030 0.961 
T | 0.969 0.967 0.910 0.936 0.001 0.001 0.001 
Position count matrix (PCM)
A |   0   0   3   0   0   0   3 
C |   0   3   6   6 100  97   0 
G |   3   0   0   0   0   3  96 
T |  96  96  91  93   0   0   0 
Position weight matrix (PWM)
A | -5.77 -5.77 -2.37 -5.77 -5.77 -5.77 -2.10 
C | -5.19 -1.70 -1.08 -1.03  1.71  1.68 -5.19 
G | -1.76 -5.19 -5.19 -5.19 -5.19 -1.79  1.68 
T |  1.11  1.11  1.05  1.07 -5.77 -5.77 -5.77 
RGT1Zhu et. al.P = 5.55e-05View matrix ↘
Sequence logo for RGT1
Fisher’s P-value5.55e-05
Information content12.21
Max PWM score11.84
Recommended cutoff11.01
Position frequency matrix (PFM)
A | 0.12 0.01 0.01 0.01 0.97 0.66 0.63 0.95 0.78 0.10 0.23 
C | 0.52 0.97 0.01 0.01 0.01 0.01 0.13 0.01 0.01 0.38 0.20 
G | 0.08 0.01 0.97 0.97 0.01 0.06 0.05 0.01 0.01 0.01 0.04 
T | 0.28 0.01 0.01 0.01 0.01 0.28 0.19 0.03 0.20 0.51 0.53 
Position count matrix (PCM)
A |  12   1   1   1  97  66  63  95  78  10  23 
C |  52  97   1   1   1   1  13   1   1  38  20 
G |   8   1  97  97   1   6   5   1   1   1   4 
T |  28   1   1   1   1  28  19   3  20  51  53 
Position weight matrix (PWM)
A | -0.98 -3.47 -3.47 -3.47  1.11  0.72  0.68  1.09  0.89 -1.16 -0.33 
C |  1.06  1.68 -2.89 -2.89 -2.89 -2.89 -0.33 -2.89 -2.89  0.75  0.11 
G | -0.81 -2.89  1.68  1.68 -2.89 -1.10 -1.28 -2.89 -2.89 -2.89 -1.50 
T | -0.13 -3.47 -3.47 -3.47 -3.47 -0.13 -0.52 -2.37 -0.47  0.47  0.50 
RGT1Zhao and StormoP = 0.002144View matrix ↘
Sequence logo for RGT1
Fisher’s P-value0.002144
Information content7.094
Max PWM score7.53
Recommended cutoff7.21
Position frequency matrix (PFM)
A | 0.074 0.008 0.013 0.778 0.469 0.369 0.716 0.553 
C | 0.784 0.030 0.071 0.056 0.059 0.198 0.043 0.022 
G | 0.057 0.958 0.909 0.112 0.131 0.137 0.034 0.043 
T | 0.085 0.004 0.007 0.054 0.341 0.296 0.207 0.382 
Position count matrix (PCM)
A |   7   0   1  77  46  36  71  55 
C |  78   3   7   5   5  19   4   2 
G |   5  95  90  11  13  13   3   4 
T |   8   0   0   5  34  29  20  38 
Position weight matrix (PWM)
A | -1.46 -3.69 -3.20  0.89  0.38  0.14  0.81  0.55 
C |  1.47 -1.79 -0.93 -1.17 -1.12  0.10 -1.43 -2.10 
G | -1.15  1.67  1.62 -0.47 -0.32 -0.27 -1.67 -1.43 
T | -1.33 -4.38 -3.82 -1.78  0.06 -0.08 -0.44  0.18 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 37 genes

YBR001C, YDL063C, YDL189W, YDL190C, YER028C, YER029C, YER030W, YFR032C, YGL181W, YGL182C, YGL209W, YHR094C, YHR095W, YIL039W, YJL013C, YJL219W, YJL221C, YJR008W, YJR043C, YKL075C, YKL076C, YKL197C, YKR075C, YLL016W, YLR098C, YLR121C, YML051W, YNL247W, YNL248C, YOL156W, YOL157C, YOR167C, YOR168W, YOR170W, YOR232W, YPL130W, YPL172C

Genes affected by TF deletion 151 genes

YCR040W, YGR280C, YJR020W, YOR225W, YGL009C, YBR031W, YCR013C, YGR279C, YKR038C, YKR042W, YKR013W, YMR044W, YOR226C, YHR142W, YHR143W-A, YLR089C, YPL048W, YCR073W-A, YFR005C, YHR025W, YIR034C, YLR340W, YLR372W, YOR351C, YPL187W, YGR180C, YHR208W, YML085C, YNL337W, YBR067C, YDR461W, YHR026W, YJR117W, YLR339C, YNL110C, YNL146W, YOL073C, YPR013C, YPR015C, YCL012W, YCL018W, YIL015W, YML055W, YNL300W, YLR287C-A, YFR044C, YLR439W, YNL279W, YER152C, YER154W, YIL153W, YJR148W, YAL012W, YAL014C, YER001W, YOR040W, YDR502C, YFL018C, YLR380W, YOL144W, YOL086C, YPL195W, YBL062W, YBR265W, YDL198C, YGR192C, YKL209C, YKL178C, YPL092W, YHR094C, YIR004W, YLR343W, YLR349W, YMR083W, YOL111C, YOL143C, YOR221C, YBL032W, YJL158C, YKL177W, YKR093W, YMR057C, YOR239W, YHR190W, YLR040C, YLR420W, YPL033C, YCL066W, YHR005C-A, YKR086W, YML126C, YOR210W, YAL022C, YKL120W, YLR041W, YOR084W, YPR125W, YCR097W, YFL026W, YHR072W-A, YOL156W, YOL126C, YPR066W, YGL089C, YBR145W, YFL023W, YGR080W, YOR366W, YJR004C, YKL216W, YNR044W, YNL322C, YPL163C, YGL225W, YHL004W, YHL009W-A, YIL170W, YLR303W, YOR245C, YOR247W, YOR249C, YPL229W, YPL262W, YKL201C, YAR053W, YEL038W, YGR172C, YGR176W, YLR453C, YML019W, YOR093C, YOR063W, YDR285W, YLR302C, YNL045W, YOR246C, YOR248W, YGL032C, YBR118W, YFL037W, YLR019W, YOR034C, YCL009C, YDL184C, YGR274C, YJR009C, YKL164C, YLR180W, YMR276W, YKL038W, YER073W

Genes supported by both experiments 2 genes

YHR094C, YOL156W

Predicted TF–TF partners 8 genes

EDS1, GSM1, MIG1, MIG3, OAF1, PDR3, SUT1, YPR196W

Explore 8 original interaction plots →