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RDS1

YCR106W

View at SGD ↗

Zinc cluster transcription factor involved in conferring resistance to cycloheximide

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Zhu et. al.
Fisher’s P-value2.27e-13
Information content14.69
Max PWM score11.82
Recommended cutoff10.9
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.80 
C | 0.01 0.97 0.05 0.02 0.96 0.93 0.01 0.18 
G | 0.18 0.01 0.93 0.96 0.02 0.05 0.97 0.01 
T | 0.80 0.01 0.01 0.01 0.01 0.01 0.01 0.01 
Position count matrix (PCM)
A |   1   1   1   1   1   1   1  80 
C |   1  97   5   2  96  93   1  18 
G |  18   1  93  96   2   5  97   1 
T |  80   1   1   1   1   1   1   1 
Position weight matrix (PWM)
A | -3.47 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47  0.92 
C | -2.89  1.68 -1.28 -2.20  1.67  1.64 -2.89  0.00 
G |  0.00 -2.89  1.64  1.67 -2.20 -1.28  1.68 -2.89 
T |  0.92 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 8

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

RDS1Badis et. al.P = 3.33e-10View matrix ↘
Sequence logo for RDS1
Fisher’s P-value3.33e-10
Information content11.37
Max PWM score9.62
Recommended cutoff9.62
Position frequency matrix (PFM)
A | 0.01 0.01 0.01 0.01 0.01 0.01 
C | 0.91 0.11 0.01 0.82 0.93 0.11 
G | 0.01 0.87 0.97 0.16 0.05 0.87 
T | 0.07 0.01 0.01 0.01 0.01 0.01 
Position count matrix (PCM)
A |   1   1   1   1   1   1 
C |  91  11   1  82  93  11 
G |   1  87  97  16   5  87 
T |   7   1   1   1   1   1 
Position weight matrix (PWM)
A | -3.47 -3.47 -3.47 -3.47 -3.47 -3.47 
C |  1.62 -0.49 -2.89  1.52  1.64 -0.49 
G | -2.89  1.58  1.68 -0.12 -1.28  1.58 
T | -1.52 -3.47 -3.47 -3.47 -3.47 -3.47 
RDS1_AFoat et. al.P = 4.37e-11View matrix ↘
Sequence logo for RDS1_A
Fisher’s P-value4.37e-11
Information content15.96
Max PWM score14.16
Recommended cutoff9.8
Position frequency matrix (PFM)
A | 0.09 0.01 0.01 0.01 0.01 0.02 0.02 0.01 0.58 0.28 
C | 0.57 0.01 0.95 0.01 0.14 0.96 0.97 0.01 0.01 0.51 
G | 0.33 0.87 0.03 0.86 0.85 0.01 0.01 0.97 0.01 0.17 
T | 0.01 0.11 0.01 0.13 0.01 0.01 0.01 0.01 0.41 0.04 
Position count matrix (PCM)
A |   9   1   1   1   1   2   2   1  57  28 
C |  56   1  95   1  14  96  97   1   1  51 
G |  33  87   3  86  85   1   1  97   1  17 
T |   1  11   1  13   1   1   1   1  41   4 
Position weight matrix (PWM)
A | -1.27 -3.47 -3.47 -3.47 -3.47 -2.77 -2.77 -3.47  0.59 -0.13 
C |  1.15 -2.89  1.66 -2.89 -0.25  1.67  1.68 -2.89 -2.89  1.04 
G |  0.61  1.58 -1.79  1.56  1.55 -2.89 -2.89  1.68 -2.89 -0.06 
T | -3.47 -1.07 -3.47 -0.90 -3.47 -3.47 -3.47 -3.47  0.25 -2.08 
RDS1_BFoat et. al.P = 1View matrix ↘
Sequence logo for RDS1_B
Fisher’s P-value1
Information content12.83
Max PWM score14.31
Recommended cutoff10.73
Position frequency matrix (PFM)
A | 0.41 0.16 0.01 0.09 0.83 0.07 0.13 0.96 0.01 0.20 0.03 0.07 0.06 
C | 0.01 0.42 0.41 0.88 0.13 0.01 0.04 0.01 0.01 0.10 0.40 0.84 0.48 
G | 0.39 0.01 0.32 0.01 0.01 0.75 0.65 0.01 0.24 0.70 0.01 0.01 0.44 
T | 0.20 0.41 0.27 0.02 0.03 0.16 0.17 0.02 0.74 0.01 0.57 0.08 0.02 
Position count matrix (PCM)
A |  41  16   1   9  83   7  13  96   1  20   3   7   6 
C |   1  42  41  88  13   1   4   1   1  10  40  84  48 
G |  39   1  32   1   1  75  65   1  24  70   1   1  44 
T |  20  41  27   2   3  16  17   2  74   1  56   8   2 
Position weight matrix (PWM)
A |  0.25 -0.69 -3.47 -1.27  0.95 -1.52 -0.90  1.10 -3.47 -0.47 -2.37 -1.52 -1.67 
C | -2.89  0.85  0.82  1.59 -0.33 -2.89 -1.50 -2.89 -2.89 -0.59  0.80  1.54  0.98 
G |  0.77 -2.89  0.58 -2.89 -2.89  1.43  1.28 -2.89  0.29  1.36 -2.89 -2.89  0.89 
T | -0.47  0.25 -0.17 -2.77 -2.37 -0.69 -0.63 -2.77  0.84 -3.47  0.58 -1.39 -2.77 
RDS1Harbison et. al.P = 2.27e-13View matrix ↘
Sequence logo for RDS1
Fisher’s P-value2.27e-13
Information content13.07
Max PWM score11.32
Recommended cutoff10.75
Position frequency matrix (PFM)
A | 0.095 0.013 0.035 0.034 0.013 0.012 0.011 0.660 
C | 0.075 0.966 0.005 0.043 0.915 0.944 0.006 0.188 
G | 0.201 0.011 0.950 0.895 0.046 0.005 0.971 0.069 
T | 0.629 0.010 0.009 0.027 0.026 0.039 0.012 0.083 
Position count matrix (PCM)
A |   9   1   3   3   1   1   1  66 
C |   7  96   0   4  91  94   0  18 
G |  20   1  95  89   4   0  97   6 
T |  62   1   0   2   2   3   1   8 
Position weight matrix (PWM)
A | -1.21 -3.20 -2.21 -2.24 -3.20 -3.28 -3.37  0.72 
C | -0.88  1.68 -3.58 -1.43  1.63  1.66 -3.40  0.04 
G |  0.11 -2.80  1.66  1.60 -1.36 -3.58  1.69 -0.96 
T |  0.68 -3.47 -3.57 -2.47 -2.51 -2.10 -3.28 -1.35 
RDS1Macisaac et. alP = 3.33e-10View matrix ↘
Sequence logo for RDS1
Fisher’s P-value3.33e-10
Information content14.63
Max PWM score10.26
Recommended cutoff10.26
Position frequency matrix (PFM)
A | 0.001 0.001 0.001 0.001 0.001 0.001 
C | 0.997 0.001 0.001 0.997 0.997 0.001 
G | 0.001 0.997 0.997 0.001 0.001 0.997 
T | 0.001 0.001 0.001 0.001 0.001 0.001 
Position count matrix (PCM)
A |   0   0   0   0   0   0 
C |  99   0   0  99  99   0 
G |   0  99  99   0   0  99 
T |   0   0   0   0   0   0 
Position weight matrix (PWM)
A | -5.77 -5.77 -5.77 -5.77 -5.77 -5.77 
C |  1.71 -5.19 -5.19  1.71  1.71 -5.19 
G | -5.19  1.71  1.71 -5.19 -5.19  1.71 
T | -5.77 -5.77 -5.77 -5.77 -5.77 -5.77 
RDS1Morozov et. al.P = 1.49e-12View matrix ↘
Sequence logo for RDS1
Fisher’s P-value1.49e-12
Information content10.27
Max PWM score10.21
Recommended cutoff10.21
Position frequency matrix (PFM)
A | 0.028 0.040 0.036 0.080 0.120 0.028 0.801 
C | 0.925 0.038 0.051 0.770 0.719 0.015 0.009 
G | 0.032 0.864 0.888 0.081 0.037 0.935 0.044 
T | 0.015 0.058 0.024 0.069 0.125 0.023 0.146 
Position count matrix (PCM)
A |   2   4   3   8  12   2  80 
C |  92   3   5  77  71   1   0 
G |   3  86  88   8   3  93   4 
T |   1   5   2   6  12   2  14 
Position weight matrix (PWM)
A | -2.44 -2.08 -2.18 -1.39 -0.98 -2.44  0.92 
C |  1.64 -1.56 -1.26  1.45  1.38 -2.48 -3.00 
G | -1.73  1.57  1.60 -0.80 -1.58  1.65 -1.41 
T | -3.06 -1.71 -2.59 -1.53 -0.94 -2.63 -0.78 
RDS1Pachkov et alP = 8.25e-14View matrix ↘
Sequence logo for RDS1
Fisher’s P-value8.25e-14
Information content14.21
Max PWM score11.55
Recommended cutoff10.43
Position frequency matrix (PFM)
A | 0.001 0.001 0.001 0.001 0.001 0.054 0.644 0.253 
C | 0.955 0.001 0.021 1.000 0.820 0.001 0.256 0.438 
G | 0.001 1.000 0.979 0.001 0.180 0.946 0.013 0.225 
T | 0.045 0.001 0.001 0.001 0.001 0.001 0.087 0.084 
Position count matrix (PCM)
A |   0   0   0   0   0   5  64  25 
C |  95   0   2 100  82   0  25  43 
G |   0 100  97   0  18  94   1  22 
T |   4   0   0   0   0   0   8   8 
Position weight matrix (PWM)
A | -5.77 -5.77 -5.77 -5.77 -5.77 -1.78  0.70 -0.23 
C |  1.67 -5.19 -2.15  1.71  1.52 -5.19  0.35  0.89 
G | -5.19  1.71  1.69 -5.19  0.00  1.66 -2.63  0.22 
T | -1.96 -5.77 -5.77 -5.77 -5.77 -5.77 -1.30 -1.34 
RDS1Zhao and StormoP = 0.000659View matrix ↘
Sequence logo for RDS1
Fisher’s P-value0.000659
Information content7.096
Max PWM score6.59
Recommended cutoff4.9
Position frequency matrix (PFM)
A | 0.094 0.001 0.001 0.001 0.300 
C | 0.075 0.861 0.001 0.085 0.294 
G | 0.575 0.001 0.997 0.913 0.306 
T | 0.256 0.137 0.001 0.001 0.100 
Position count matrix (PCM)
A |   9   0   0   0  30 
C |   7  86   0   8  29 
G |  57   0  99  91  30 
T |  25  13   0   0  10 
Position weight matrix (PWM)
A | -1.23 -5.77 -5.77 -5.77 -0.06 
C | -0.88  1.57 -5.19 -0.75  0.49 
G |  1.16 -5.19  1.71  1.62  0.53 
T | -0.22 -0.85 -5.77 -5.77 -1.16 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 31 genes

YCL055W, YCL056C, YCR105W, YCR106W, YCR107W, YDR144C, YDR145W, YER138C, YGL157W, YGR004W, YGR175C, YGR176W, YGR225W, YKL118W, YKL177W, YKL179C, YLR083C, YLR433C, YLR434C, YMR103C, YMR125W, YMR126C, YMR257C, YMR259C, YNL188W, YNL258C, YPL070W, YPL071C, YPL073C, YPR158W-A, YPR158W-B

Genes affected by TF deletion 111 genes

YOL047C, YDR216W, YDR190C, YDR222W, YGL045W, YGR152C, YHR180W, YJL051W, YKL049C, YMR220W, YNL271C, YBL083C, YBR029C, YBL085W, YBR001C, YCR041W, YCR015C, YCR043C, YDR003W, YDR005C, YDR065W, YDR369C, YDR401W, YDR433W, YDR371W, YDR403W, YDR435C, YER111C, YGL229C, YGL170C, YGL202W, YHL045W, YGR281W, YHL015W, YIL077C, YIL141W, YIL111W, YJR049C, YJR084W, YJR021C, YKR013W, YML113W, YOR254C, YDL127W, YFR033C, YPL014W, YCR106W, YMR103C, YGR250C, YML027W, YCR107W, YJL017W, YMR104C, YMR136W, YNL116W, YDR279W, YPR191W, YER042W, YCR021C, YDR074W, YOR267C, YPL247C, YDL076C, YKL051W, YER150W, YMR023C, YMR199W, YOR074C, YOR384W, YFR017C, YKL026C, YMR078C, YMR145C, YNL309W, YIR035C, YJR119C, YOR324C, YBR264C, YER064C, YPL087W, YGL183C, YGR292W, YOR273C, YGR138C, YNL289W, YNL035C, YAR018C, YGR139W, YDL048C, YDR177W, YNL159C, YNL160W, YGL154C, YBR054W, YER139C, YGL223C, YLR297W, YDL150W, YPR106W, YDR055W, YIL103W, YMR034C, YMR181C, YMR250W, YOR092W, YCL040W, YDR155C, YDR523C, YOL101C, YOL165C, YNR019W

Genes supported by both experiments 3 genes

YCR106W, YCR107W, YMR103C

Predicted TF–TF partners 6 genes

HAP2, HAP4, OAF1, PHD1, STB1, SWI4

Explore 6 original interaction plots →