← All factors / TF RECORD

PPR1

YLR014C

View at SGD ↗

Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Foat et. al.
Fisher’s P-value0.000853
Information content17.23
Max PWM score15.69
Recommended cutoff10.24
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.05 0.01 0.57 0.97 0.93 0.01 0.01 0.35 0.01 0.01 0.01 0.29 0.08 0.01 
C | 0.01 0.01 0.01 0.01 0.02 0.01 0.35 0.33 0.97 0.01 0.89 0.01 0.01 0.01 
G | 0.01 0.10 0.42 0.01 0.01 0.97 0.01 0.01 0.01 0.01 0.01 0.48 0.23 0.80 
T | 0.93 0.89 0.01 0.01 0.03 0.01 0.63 0.31 0.01 0.97 0.09 0.22 0.68 0.18 
Position count matrix (PCM)
A |   5   1  56  97  93   1   1  35   1   1   1  28   8   1 
C |   1   1   1   1   2   1  35  33  97   1  89   1   1   1 
G |   1  10  42   1   1  97   1   1   1   1   1  48  23  80 
T |  93  89   1   1   3   1  63  31   1  97   9  22  68  18 
Position weight matrix (PWM)
A | -1.86 -3.47  0.58  1.11  1.07 -3.47 -3.47  0.09 -3.47 -3.47 -3.47 -0.10 -1.39 -3.47 
C | -2.89 -2.89 -2.89 -2.89 -2.20 -2.89  0.66  0.61  1.68 -2.89  1.60 -2.89 -2.89 -2.89 
G | -2.89 -0.59  0.85 -2.89 -2.89  1.68 -2.89 -2.89 -2.89 -2.89 -2.89  0.98  0.25  1.49 
T |  1.07  1.02 -3.47 -3.47 -2.37 -3.47  0.68 -0.03 -3.47  1.11 -1.27 -0.37  0.75 -0.58 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 1

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

PPR1Morozov et. al.P = 0.5151View matrix ↘
Sequence logo for PPR1
Fisher’s P-value0.5151
Information content15
Max PWM score15.75
Recommended cutoff8.14
Position frequency matrix (PFM)
A | 0.013 0.013 0.031 0.043 0.507 0.255 0.747 0.810 0.013 0.244 0.081 0.054 0.013 0.546 
C | 0.115 0.936 0.023 0.031 0.407 0.247 0.101 0.061 0.145 0.250 0.877 0.872 0.110 0.185 
G | 0.021 0.039 0.740 0.897 0.065 0.468 0.123 0.013 0.294 0.377 0.029 0.021 0.865 0.249 
T | 0.851 0.013 0.207 0.029 0.021 0.030 0.029 0.116 0.548 0.129 0.013 0.053 0.013 0.020 
Position count matrix (PCM)
A |   1   1   3   4  50  25  74  81   1  24   8   5   1  54 
C |  11  93   2   3  40  24  10   6  14  25  87  87  11  18 
G |   2   3  74  89   6  46  12   1  29  37   2   2  86  24 
T |  85   1  20   2   2   3   2  11  54  12   1   5   1   2 
Position weight matrix (PWM)
A | -3.20 -3.20 -2.33 -2.01  0.46 -0.23  0.85  0.93 -3.20 -0.27 -1.37 -1.78 -3.20  0.53 
C | -0.45  1.65 -2.06 -1.76  0.82  0.32 -0.58 -1.08 -0.22  0.33  1.58  1.58 -0.49  0.03 
G | -2.15 -1.53  1.41  1.61 -1.02  0.96 -0.38 -2.63  0.49  0.74 -1.83 -2.15  1.57  0.32 
T |  0.98 -3.20 -0.44 -2.40 -2.72 -2.37 -2.40 -1.01  0.54 -0.91 -3.20 -1.80 -3.20 -2.77 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 106 genes

YAL060W, YBL018C, YBL068W, YBL070C, YBR065C, YBR109C, YBR110W, YBR127C, YBR214W, YCR039C, YCR040W, YCR041W, YDL054C, YDL092W, YDL094C, YDL141W, YDL142C, YDL156W, YDL157C, YDL158C, YDL159W, YDL160C, YDL175C, YDR020C, YDR021W, YDR028C, YDR029W, YDR048C, YDR061W, YDR084C, YDR136C, YDR138W, YDR142C, YDR183W, YDR294C, YDR375C, YDR376W, YDR440W, YEL010W, YER008C, YER009W, YER022W, YFR001W, YGL130W, YGL131C, YGL134W, YGL143C, YGL144C, YGR145W, YGR177C, YGR188C, YGR225W, YGR261C, YHR164C, YIL038C, YIL161W, YJL023C, YJL145W, YJL179W, YJL180C, YJL203W, YJL204C, YKL145W, YKL147C, YKL202W, YKL203C, YKR014C, YKR022C, YKR023W, YKR035C, YKR051W, YLR239C, YLR240W, YLR288C, YLR289W, YLR418C, YLR419W, YLR429W, YML077W, YMR060C, YMR061W, YMR126C, YNL009W, YNL111C, YNL247W, YNL248C, YNL299W, YNL321W, YNL322C, YNL323W, YNL325C, YNR054C, YOL083W, YOL095C, YOR021C, YOR040W, YOR090C, YOR091W, YOR093C, YOR094W, YOR112W, YOR296W, YPL129W, YPR049C, YPR051W, YPR081C

Genes affected by TF deletion 54 genes

YGR278W, YHL014C, YML114C, YHR146W, YDR207C, YMR042W, YOR226C, YPL177C, YKL170W, YMR314W, YBR093C, YBR129C, YMR102C, YDR281C, YER029C, YKL142W, YKL206C, YLR119W, YOR132W, YBR044C, YLR257W, YNL088W, YAR015W, YGR132C, YJL123C, YLR438C-A, YOR075W, YKR080W, YFR041C, YLR099C, YGL153W, YOL144W, YBL060W, YHR215W, YGR012W, YOL143C, YAR071W, YPR167C, YIL130W, YLR420W, YNL289W, YGR137W, YKL030W, YKL001C, YOL126C, YLR014C, YKL216W, YDR088C, YHR200W, YBR244W, YHR135C, YLR079W, YPL040C, YGR089W