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OPI1

YHL020C

View at SGD ↗

Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Foat et. al.
Fisher’s P-value0.2521
Information content9.949
Max PWM score10.75
Recommended cutoff7.14
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.19 0.05 0.14 0.09 0.04 0.43 0.91 0.44 0.01 0.10 
C | 0.24 0.01 0.01 0.01 0.90 0.01 0.07 0.16 0.32 0.77 
G | 0.55 0.81 0.09 0.01 0.05 0.56 0.01 0.17 0.02 0.10 
T | 0.03 0.14 0.77 0.89 0.01 0.01 0.01 0.23 0.66 0.03 
Position count matrix (PCM)
A |  19   5  14   9   4  43  91  44   1  10 
C |  24   1   1   1  90   1   7  16  32  77 
G |  55  81   9   1   5  56   1  17   2  10 
T |   3  14  77  89   1   1   1  23  66   3 
Position weight matrix (PWM)
A | -0.52 -1.86 -0.83 -1.27 -2.08  0.30  1.05  0.32 -3.47 -1.16 
C |  0.29 -2.89 -2.89 -2.89  1.61 -2.89 -0.94 -0.12  0.58  1.45 
G |  1.12  1.50 -0.69 -2.89 -1.28  1.13 -2.89 -0.06 -2.20 -0.59 
T | -2.37 -0.83  0.88  1.02 -3.47 -3.47 -3.47 -0.33  0.72 -2.37 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 2

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

OPI1Harbison et. al.P = 0.7927View matrix ↘
Sequence logo for OPI1
Fisher’s P-value0.7927
Information content11.59
Max PWM score9.34
Recommended cutoff4.95
Position frequency matrix (PFM)
A | 0.012 0.012 0.012 0.965 0.965 0.012 0.012 
C | 0.012 0.965 0.012 0.012 0.012 0.488 0.965 
G | 0.012 0.012 0.965 0.012 0.012 0.012 0.012 
T | 0.965 0.012 0.012 0.012 0.012 0.488 0.012 
Position count matrix (PCM)
A |   1   1   1  96  96   1   1 
C |   1  96   1   1   1  48  96 
G |   1   1  96   1   1   1   1 
T |  96   1   1   1   1  48   1 
Position weight matrix (PWM)
A | -3.28 -3.28 -3.28  1.10  1.10 -3.28 -3.28 
C | -2.71  1.68 -2.71 -2.71 -2.71  1.00  1.68 
G | -2.71 -2.71  1.68 -2.71 -2.71 -2.71 -2.71 
T |  1.10 -3.28 -3.28 -3.28 -3.28  0.42 -3.28 
OPI1Macisaac et. alP = 0.3819View matrix ↘
Sequence logo for OPI1
Fisher’s P-value0.3819
Information content10.48
Max PWM score8.74
Recommended cutoff7.56
Position frequency matrix (PFM)
A | 0.218 0.001 0.980 0.997 0.018 0.018 0.364 
C | 0.400 0.001 0.018 0.001 0.963 0.980 0.218 
G | 0.164 0.997 0.001 0.001 0.001 0.001 0.327 
T | 0.218 0.001 0.001 0.001 0.018 0.001 0.091 
Position count matrix (PCM)
A |  21   0  98  99   1   1  36 
C |  40   0   1   0  96  98  21 
G |  16  99   0   0   0   0  32 
T |  21   0   0   0   1   0   9 
Position weight matrix (PWM)
A | -0.38 -5.77  1.12  1.14 -2.88 -2.88  0.13 
C |  0.80 -5.19 -2.30 -5.19  1.68  1.69  0.19 
G | -0.09  1.71 -5.19 -5.19 -5.19 -5.19  0.60 
T | -0.38 -5.77 -5.77 -5.77 -2.88 -5.77 -1.26 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 29 genes

YAR009C, YAR050W, YBR029C, YBR030W, YDR146C, YDR147W, YDR194C, YDR195W, YDR497C, YFR029W, YFR036W, YGR256W, YHR005C-A, YIL102C, YJL148W, YJL152W, YJL153C, YJL191W, YJL192C, YJR100C, YKL182W, YLL004W, YLL005C, YLR011W, YNL129W, YNL130C, YOR236W, YPL198W, YPL231W

Genes affected by TF deletion 133 genes

YGL230C, YNL052W, YJL115W, YKL043W, YOR065W, YPL019C, YPL053C, YBR029C, YIL143C, YDL127W, YFR033C, YGR151C, YGR157W, YJL048C, YLR460C, YPL016W, YPL052W, YPR140W, YHR053C, YHR055C, YOL108C, YER026C, YGL077C, YML027W, YOR097C, YOR129C, YBR129C, YDR497C, YGR004W, YLL061W, YOL107W, YDR275W, YJL210W, YKL142W, YIL124W, YNL089C, YOR229W, YHR123W, YMR173W, YHR004C, YLR253W, YNL090W, YOR230W, YOR264W, YGR131W, YLR099C, YMR199W, YOR074C, YPL026C, YDR502C, YIR042C, YLR005W, YLR380W, YNR016C, YJL153C, YJL185C, YKL182W, YLR132C, YNR035C, YPL156C, YGR040W, YMR144W, YOR298C-A, YOR328W, YLR191W, YLR133W, YMR030W, YNL065W, YOL002C, YBR177C, YGL055W, YNL257C, YNL289W, YKR056W, YNL098C, YOL032W, YPL188W, YMR173W-A, YNL256W, YPL061W, YHR067W, YKL001C, YLR352W, YNL191W, YOL154W, YER043C, YGR260W, YGR234W, YIL034C, YJL167W, YLR136C, YLR168C, YLR172C, YMR300C, YMR272C, YDR481C, YKL027W, YJR133W, YER044C, YGR259C, YJL196C, YER091C, YHR018C, YJR104C, YNL044W, YPL231W, YDR274C, YGR176W, YHR200W, YJL079C, YJR073C, YLR241W, YMR038C, YNL043C, YBR178W, YBR244W, YGR149W, YGR177C, YJL142C, YLR049C, YPL042C, YDR124W, YFR030W, YNL141W, YKR004C, YDR123C, YNL170W, YOL101C, YOL103W, YOR306C, YPR069C, YLR173W, YNR019W

Genes supported by both experiments 5 genes

YBR029C, YDR497C, YJL153C, YKL182W, YPL231W

Predicted TF–TF partners 1 genes

STP3

Explore 1 original interaction plots →