← All factors / TF RECORD

MIG3

YER028C

View at SGD ↗

Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Zhu et. al.
Fisher’s P-value6.93e-05
Information content14.53
Max PWM score13.38
Recommended cutoff11.67
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.22 0.75 0.01 0.01 0.01 0.01 0.21 0.01 0.84 0.33 0.25 
C | 0.11 0.10 0.97 0.95 0.97 0.97 0.01 0.92 0.02 0.11 0.10 
G | 0.06 0.11 0.01 0.01 0.01 0.01 0.77 0.07 0.13 0.06 0.02 
T | 0.62 0.04 0.01 0.03 0.01 0.01 0.01 0.01 0.01 0.51 0.63 
Position count matrix (PCM)
A |  22  75   1   1   1   1  21   1  84  33  25 
C |  11  10  97  95  97  97   1  92   2  11  10 
G |   6  11   1   1   1   1  77   7  13   6   2 
T |  62   4   1   3   1   1   1   1   1  51  63 
Position weight matrix (PWM)
A | -0.37  0.85 -3.47 -3.47 -3.47 -3.47 -0.42 -3.47  0.97  0.03 -0.25 
C | -0.49 -0.59  1.68  1.66  1.68  1.68 -2.89  1.63 -2.20 -0.49 -0.59 
G | -1.10 -0.49 -2.89 -2.89 -2.89 -2.89  1.45 -0.94 -0.33 -1.10 -2.20 
T |  0.66 -2.08 -3.47 -2.37 -3.47 -3.47 -3.47 -3.47 -3.47  0.47  0.68 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 3

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

MIG3Badis et. al.P = 0.02125View matrix ↘
Sequence logo for MIG3
Fisher’s P-value0.02125
Information content10.55
Max PWM score9.14
Recommended cutoff8.26
Position frequency matrix (PFM)
A | 0.01 0.01 0.01 0.01 0.41 0.05 
C | 0.97 0.92 0.97 0.97 0.02 0.69 
G | 0.01 0.01 0.01 0.01 0.56 0.17 
T | 0.01 0.06 0.01 0.01 0.01 0.09 
Position count matrix (PCM)
A |   1   1   1   1  41   5 
C |  97  92  97  97   2  69 
G |   1   1   1   1  56  17 
T |   1   6   1   1   1   9 
Position weight matrix (PWM)
A | -3.47 -3.47 -3.47 -3.47  0.25 -1.86 
C |  1.68  1.63  1.68  1.68 -2.20  1.34 
G | -2.89 -2.89 -2.89 -2.89  1.13 -0.06 
T | -3.47 -1.67 -3.47 -3.47 -3.47 -1.27 
MIG3Foat et. al.P = 0.01331View matrix ↘
Sequence logo for MIG3
Fisher’s P-value0.01331
Information content16.84
Max PWM score15.8
Recommended cutoff11.14
Position frequency matrix (PFM)
A | 0.12 0.03 0.01 0.87 0.01 0.05 0.05 0.01 0.96 0.14 0.02 0.01 
C | 0.52 0.01 0.02 0.01 0.01 0.01 0.01 0.02 0.01 0.01 0.66 0.03 
G | 0.03 0.95 0.77 0.11 0.97 0.93 0.93 0.01 0.01 0.59 0.01 0.11 
T | 0.33 0.01 0.21 0.01 0.01 0.01 0.01 0.96 0.02 0.26 0.32 0.85 
Position count matrix (PCM)
A |  12   3   1  87   1   5   5   1  96  14   2   1 
C |  52   1   2   1   1   1   1   2   1   1  66   3 
G |   3  95  77  11  97  93  93   1   1  59   1  11 
T |  33   1  21   1   1   1   1  96   2  26  32  85 
Position weight matrix (PWM)
A | -0.98 -2.37 -3.47  1.00 -3.47 -1.86 -1.86 -3.47  1.10 -0.83 -2.77 -3.47 
C |  1.06 -2.89 -2.20 -2.89 -2.89 -2.89 -2.89 -2.20 -2.89 -2.89  1.30 -1.79 
G | -1.79  1.66  1.45 -0.49  1.68  1.64  1.64 -2.89 -2.89  1.19 -2.89 -0.49 
T |  0.03 -3.47 -0.42 -3.47 -3.47 -3.47 -3.47  1.10 -2.77 -0.21  0.00  0.98 
MIG3Zhao and StormoP = 0.02125View matrix ↘
Sequence logo for MIG3
Fisher’s P-value0.02125
Information content7.492
Max PWM score8.19
Recommended cutoff7.21
Position frequency matrix (PFM)
A | 0.118 0.001 0.001 0.001 0.342 0.105 
C | 0.671 0.728 0.947 0.921 0.039 0.560 
G | 0.057 0.024 0.001 0.077 0.515 0.202 
T | 0.154 0.247 0.051 0.001 0.104 0.133 
Position count matrix (PCM)
A |  11   0   0   0  34  10 
C |  67  72  94  92   3  56 
G |   5   2   0   7  51  20 
T |  15  24   5   0  10  13 
Position weight matrix (PWM)
A | -1.00 -5.77 -5.77 -5.77  0.07 -1.11 
C |  1.32  1.40  1.66  1.63 -1.53  1.13 
G | -1.15 -2.01 -5.19 -0.85  1.05  0.12 
T | -0.73 -0.26 -1.84 -5.77 -1.12 -0.88 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 33 genes

YAR050W, YBR012W-A, YBR012W-B, YBR099C, YBR229C, YCR018C-A, YCR019W, YDL214C, YDL245C, YDL246C, YDR040C, YDR041W, YDR042C, YDR084C, YDR343C, YEL070W, YER189W, YER190W, YFR017C, YHR033W, YJL148W, YJL219W, YJL221C, YJR158W, YJR159W, YLL004W, YLL005C, YLR011W, YMR258C, YOL156W, YOL157C, YOR236W, YPR142C

Genes affected by TF deletion 1 genes

No Data

Predicted TF–TF partners 27 genes

AFT2, CAT8, CEP3, CIN5, GIS1, GSM1, MIG1, MSN2, MSN4, NRG1, PDR1, PDR8, RGM1, RGT1, RPH1, RSF2, STB5, STP1, STP2, SUT1, SUT2, UME6, USV1, YER130C, YER184C, YPR196W, YRM1

Explore 27 original interaction plots →