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MIG2

YGL209W, MLZ1

View at SGD ↗

Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Zhu et. al.
Fisher’s P-value0.0005263
Information content14.92
Max PWM score13.4
Recommended cutoff7.64
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.15 0.72 0.01 0.01 0.01 0.01 0.23 0.01 0.89 0.40 0.21 
C | 0.07 0.06 0.97 0.94 0.97 0.97 0.01 0.94 0.01 0.16 0.07 
G | 0.07 0.18 0.01 0.01 0.01 0.01 0.75 0.04 0.09 0.05 0.02 
T | 0.71 0.04 0.01 0.04 0.01 0.01 0.01 0.01 0.01 0.39 0.70 
Position count matrix (PCM)
A |  15  72   1   1   1   1  23   1  89  40  21 
C |   7   6  97  94  97  97   1  94   1  16   7 
G |   7  18   1   1   1   1  75   4   9   5   2 
T |  71   4   1   4   1   1   1   1   1  39  70 
Position weight matrix (PWM)
A | -0.76  0.81 -3.47 -3.47 -3.47 -3.47 -0.33 -3.47  1.02  0.22 -0.42 
C | -0.94 -1.10  1.68  1.65  1.68  1.68 -2.89  1.65 -2.89 -0.12 -0.94 
G | -0.94  0.00 -2.89 -2.89 -2.89 -2.89  1.43 -1.50 -0.69 -1.28 -2.20 
T |  0.80 -2.08 -3.47 -2.08 -3.47 -3.47 -3.47 -3.47 -3.47  0.20  0.78 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 4

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

MIG2Badis et. al.P = 0.07194View matrix ↘
Sequence logo for MIG2
Fisher’s P-value0.07194
Information content10.77
Max PWM score9.21
Recommended cutoff8.27
Position frequency matrix (PFM)
A | 0.01 0.01 0.01 0.01 0.36 0.05 
C | 0.96 0.97 0.97 0.97 0.11 0.76 
G | 0.02 0.01 0.01 0.01 0.52 0.13 
T | 0.01 0.01 0.01 0.01 0.01 0.06 
Position count matrix (PCM)
A |   1   1   1   1  36   5 
C |  96  97  97  97  11  76 
G |   2   1   1   1  52  13 
T |   1   1   1   1   1   6 
Position weight matrix (PWM)
A | -3.47 -3.47 -3.47 -3.47  0.12 -1.86 
C |  1.67  1.68  1.68  1.68 -0.49  1.44 
G | -2.20 -2.89 -2.89 -2.89  1.06 -0.33 
T | -3.47 -3.47 -3.47 -3.47 -3.47 -1.67 
MIG2_AFoat et. al.P = 0.01204View matrix ↘
Sequence logo for MIG2_A
Fisher’s P-value0.01204
Information content16.75
Max PWM score14.53
Recommended cutoff7.36
Position frequency matrix (PFM)
A | 0.77 0.12 0.31 0.01 0.48 0.01 0.04 0.51 0.95 0.94 0.01 0.01 0.01 0.27 
C | 0.02 0.86 0.01 0.01 0.01 0.97 0.06 0.01 0.01 0.01 0.01 0.01 0.01 0.01 
G | 0.01 0.01 0.16 0.01 0.01 0.01 0.01 0.01 0.03 0.04 0.97 0.01 0.01 0.02 
T | 0.20 0.01 0.52 0.97 0.51 0.01 0.90 0.48 0.01 0.01 0.01 0.97 0.97 0.69 
Position count matrix (PCM)
A |  77  12  31   1  48   1   4  51  95  94   1   1   1  27 
C |   2  86   1   1   1  97   6   1   1   1   1   1   1   1 
G |   1   1  16   1   1   1   1   1   3   4  97   1   1   2 
T |  20   1  52  97  51   1  90  48   1   1   1  97  97  69 
Position weight matrix (PWM)
A |  0.88 -0.98 -0.03 -3.47  0.41 -3.47 -2.08  0.47  1.09  1.08 -3.47 -3.47 -3.47 -0.17 
C | -2.20  1.56 -2.89 -2.89 -2.89  1.68 -1.10 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 
G | -2.89 -2.89 -0.12 -2.89 -2.89 -2.89 -2.89 -2.89 -1.79 -1.50  1.68 -2.89 -2.89 -2.20 
T | -0.47 -3.47  0.49  1.11  0.47 -3.47  1.03  0.41 -3.47 -3.47 -3.47  1.11  1.11  0.77 
MIG2_BFoat et. al.P = 0.005217View matrix ↘
Sequence logo for MIG2_B
Fisher’s P-value0.005217
Information content19.05
Max PWM score20.17
Recommended cutoff10.11
Position frequency matrix (PFM)
A | 0.39 0.01 0.01 0.96 0.01 0.32 0.36 0.17 0.01 0.06 0.03 0.44 0.31 0.39 0.02 0.97 0.03 0.05 0.05 0.25 
C | 0.01 0.45 0.96 0.01 0.01 0.03 0.07 0.28 0.61 0.01 0.51 0.05 0.25 0.47 0.96 0.01 0.01 0.11 0.23 0.66 
G | 0.52 0.01 0.01 0.02 0.19 0.01 0.56 0.24 0.01 0.44 0.41 0.03 0.01 0.09 0.01 0.01 0.95 0.14 0.43 0.01 
T | 0.08 0.54 0.02 0.01 0.79 0.64 0.01 0.31 0.37 0.50 0.05 0.48 0.44 0.04 0.01 0.01 0.01 0.71 0.29 0.09 
Position count matrix (PCM)
A |  39   1   1  96   1  32  36  17   1   6   3  44  31  39   2  97   3   5   5  25 
C |   1  45  96   1   1   3   7  28  61   1  51   5  25  47  96   1   1  11  23  66 
G |  52   1   1   2  19   1  56  24   1  44  41   3   1   9   1   1  95  14  43   1 
T |   8  54   2   1  79  64   1  31  37  50   5  48  44   4   1   1   1  71  28   9 
Position weight matrix (PWM)
A |  0.20 -3.47 -3.47  1.10 -3.47  0.00  0.12 -0.63 -3.47 -1.67 -2.37  0.32 -0.03  0.20 -2.77  1.11 -2.37 -1.86 -1.86 -0.25 
C | -2.89  0.92  1.67 -2.89 -2.89 -1.79 -0.94  0.44  1.22 -2.89  1.04 -1.28  0.33  0.96  1.67 -2.89 -2.89 -0.49  0.25  1.30 
G |  1.06 -2.89 -2.89 -2.20  0.05 -2.89  1.13  0.29 -2.89  0.89  0.82 -1.79 -2.89 -0.69 -2.89 -2.89  1.66 -0.25  0.87 -2.89 
T | -1.39  0.52 -2.77 -3.47  0.90  0.69 -3.47 -0.03  0.15  0.45 -1.86  0.41  0.32 -2.08 -3.47 -3.47 -3.47  0.80 -0.10 -1.27 
MIG2Zhao and StormoP = 0.07194View matrix ↘
Sequence logo for MIG2
Fisher’s P-value0.07194
Information content8.906
Max PWM score8.72
Recommended cutoff7.79
Position frequency matrix (PFM)
A | 0.116 0.063 0.001 0.002 0.190 0.074 
C | 0.184 0.547 0.019 0.013 0.015 0.035 
G | 0.643 0.009 0.966 0.983 0.787 0.787 
T | 0.057 0.382 0.013 0.003 0.007 0.103 
Position count matrix (PCM)
A |  11   6   0   0  19   7 
C |  18  54   1   1   1   3 
G |  64   0  96  98  78  78 
T |   5  38   1   0   0  10 
Position weight matrix (PWM)
A | -1.01 -1.63 -5.77 -5.08 -0.52 -1.46 
C |  0.02  1.11 -2.25 -2.63 -2.48 -1.64 
G |  1.27 -3.00  1.68  1.70  1.48  1.48 
T | -1.73  0.18 -3.20 -4.67 -3.82 -1.13 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 77 genes

YAR009C, YBL068W, YBL070C, YBR032W, YBR065C, YBR109C, YBR110W, YBR120C, YBR185C, YBR186W, YBR232C, YDL091C, YDL092W, YDL094C, YDL245C, YDL246C, YDR030C, YDR031W, YDR117C, YDR118W, YDR136C, YDR138W, YDR164C, YDR165W, YDR294C, YDR343C, YDR355C, YDR411C, YDR412W, YDR473C, YEL069C, YEL070W, YER133W, YER134C, YGL195W, YGR038C-B, YGR188C, YHR005C-A, YIL035C, YIL115C, YJL049W, YJL148W, YJR010C-A, YJR088C, YJR089W, YJR100C, YJR158W, YJR159W, YKL167C, YKR003W, YLL014W, YLR199C, YLR200W, YLR273C, YLR274W, YML072C, YMR052W, YMR131C, YMR283C, YNL111C, YNL136W, YNL137C, YNL210W, YNL211C, YNR054C, YOL023W, YOL083W, YOL099C, YOR021C, YOR059C, YOR214C, YOR307C, YOR365C, YOR367W, YOR368W, YPL267W, YPR134W

Genes affected by TF deletion 26 genes

YEL012W, YMR011W, YPL016W, YMR254C, YMR072W, YNL306W, YER123W, YNL040W, YDR071C, YOL053W, YDL135C, YLR101C, YOR357C, YOR298W, YIR041W, YMR110C, YBR296C, YNL312W, YHR006W, YLR294C, YMR027W, YBR114W, YHR101C, YBR111C, YER100W, YHR197W

Predicted TF–TF partners 3 genes

RGM1, SUT1, USV1

Explore 3 original interaction plots →