S.ScerTFYeast transcription factor database Aaron Spivak
← All factors / TF RECORD

MIG1

YGL035C, TDS22, SSN1, CAT4

View at SGD ↗

Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Foat et. al.
Fisher’s P-value4.44e-08
Information content16.28
Max PWM score15.51
Recommended cutoff11.63
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.30 0.03 0.01 0.83 0.04 0.01 0.39 0.01 0.92 0.05 0.28 0.34 
C | 0.68 0.04 0.01 0.01 0.89 0.92 0.60 0.97 0.01 0.93 0.01 0.13 
G | 0.01 0.03 0.14 0.04 0.07 0.05 0.01 0.01 0.06 0.01 0.70 0.53 
T | 0.01 0.90 0.84 0.12 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01
Position count matrix (PCM)
A |  30   3   1  83   4   1  39   1  92   5  28  34 
C |  68   4   1   1  89  92  60  97   1  93   1  13 
G |   1   3  14   4   7   5   1   1   6   1  70  53 
T |   1  90  84  12   1   1   1   1   1   1   1   1
Position weight matrix (PWM)
A | -0.06 -2.37 -3.47  0.95 -2.08 -3.47  0.20 -3.47  1.06 -1.86 -0.13  0.06 
C |  1.33 -1.50 -2.89 -2.89  1.60  1.63  1.20  1.68 -2.89  1.64 -2.89 -0.33 
G | -2.89 -1.79 -0.25 -1.50 -0.94 -1.28 -2.89 -2.89 -1.10 -2.89  1.36  1.08 
T | -3.47  1.03  0.97 -0.98 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 7

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

MIG1Badis et. al.P = 0.0001561View matrix ↘
Sequence logo for MIG1
Fisher’s P-value0.0001561
Information content10.62
Max PWM score8.91
Recommended cutoff6.1
Position frequency matrix (PFM)
A | 0.01 0.01 0.01 0.01 0.46 0.05 
C | 0.97 0.97 0.97 0.97 0.03 0.58 
G | 0.01 0.01 0.01 0.01 0.50 0.30 
T | 0.01 0.01 0.01 0.01 0.01 0.07
Position count matrix (PCM)
A |   1   1   1   1  46   5 
C |  97  97  97  97   3  57 
G |   1   1   1   1  50  30 
T |   1   1   1   1   1   7
Position weight matrix (PWM)
A | -3.47 -3.47 -3.47 -3.47  0.36 -1.86 
C |  1.68  1.68  1.68  1.68 -1.79  1.17 
G | -2.89 -2.89 -2.89 -2.89  1.02  0.51 
T | -3.47 -3.47 -3.47 -3.47 -3.47 -1.52
Badis et. al.
MIG1_AFoat et. al.P = 0.1674View matrix ↘
Sequence logo for MIG1_A
Fisher’s P-value0.1674
Information content14.21
Max PWM score15.92
Recommended cutoff8.56
Position frequency matrix (PFM)
A | 0.01 0.21 0.20 0.77 0.01 0.66 0.49 0.03 0.71 0.51 0.16 0.27 0.01 0.95 0.01 0.52 0.02 0.51 
C | 0.25 0.17 0.01 0.04 0.11 0.06 0.41 0.15 0.01 0.01 0.07 0.01 0.01 0.01 0.04 0.01 0.05 0.33 
G | 0.34 0.01 0.01 0.18 0.07 0.27 0.05 0.79 0.07 0.07 0.32 0.60 0.01 0.03 0.01 0.24 0.78 0.16 
T | 0.40 0.61 0.79 0.01 0.81 0.01 0.05 0.03 0.21 0.41 0.45 0.12 0.97 0.01 0.94 0.23 0.15 0.01
Position count matrix (PCM)
A |   1  21  20  77   1  66  49   3  71  51  16  27   1  95   1  52   2  51 
C |  25  17   1   4  11   6  41  15   1   1   7   1   1   1   4   1   5  33 
G |  34   1   1  18   7  27   5  79   7   7  32  60   1   3   1  24  78  16 
T |  40  61  79   1  81   1   5   3  21  41  45  12  97   1  94  23  15   1
Position weight matrix (PWM)
A | -3.47 -0.42 -0.47  0.88 -3.47  0.72  0.43 -2.37  0.80  0.47 -0.69 -0.17 -3.47  1.09 -3.47  0.49 -2.77  0.47 
C |  0.33 -0.06 -2.89 -1.50 -0.49 -1.10  0.82 -0.18 -2.89 -2.89 -0.94 -2.89 -2.89 -2.89 -1.50 -2.89 -1.28  0.61 
G |  0.64 -2.89 -2.89  0.00 -0.94  0.41 -1.28  1.48 -0.94 -0.94  0.58  1.20 -2.89 -1.79 -2.89  0.29  1.47 -0.12 
T |  0.22  0.65  0.90 -3.47  0.93 -3.47 -1.86 -2.37 -0.42  0.25  0.34 -0.98  1.11 -3.47  1.08 -0.33 -0.76 -3.47
Foat et. al.
MIG1Macisaac et. alP = 3.36e-05View matrix ↘
Sequence logo for MIG1
Fisher’s P-value3.36e-05
Information content12.88
Max PWM score10.4
Recommended cutoff7.27
Position frequency matrix (PFM)
A | 0.488 0.488 0.488 0.488 0.012 0.012 0.012 0.012 0.012 0.012 
C | 0.012 0.012 0.012 0.012 0.488 0.488 0.012 0.012 0.012 0.012 
G | 0.012 0.012 0.012 0.012 0.488 0.012 0.964 0.964 0.964 0.964 
T | 0.488 0.488 0.488 0.488 0.012 0.488 0.012 0.012 0.012 0.012
Position count matrix (PCM)
A |  48  48  48  48   1   1   1   1   1   1 
C |   1   1   1   1  48  48   1   1   1   1 
G |   1   1   1   1  48   1  96  96  96  96 
T |  48  48  48  48   1  48   1   1   1   1
Position weight matrix (PWM)
A |  0.42  0.42  0.42  0.42 -3.28 -3.28 -3.28 -3.28 -3.28 -3.28 
C | -2.71 -2.71 -2.71 -2.71  1.00  1.00 -2.71 -2.71 -2.71 -2.71 
G | -2.71 -2.71 -2.71 -2.71  1.00 -2.71  1.68  1.68  1.68  1.68 
T |  0.42  0.42  0.42  0.42 -3.28  0.42 -3.28 -3.28 -3.28 -3.28
Macisaac et. al
MIG1Pachkov et alP = 0.002209View matrix ↘
Sequence logo for MIG1
Fisher’s P-value0.002209
Information content13.18
Max PWM score11.54
Recommended cutoff8.21
Position frequency matrix (PFM)
A | 0.125 0.125 0.001 0.001 0.625 0.001 0.625 0.125 0.375 0.375 
C | 0.875 0.875 1.000 1.000 0.001 0.250 0.001 0.125 0.001 0.001 
G | 0.001 0.001 0.001 0.001 0.250 0.750 0.125 0.001 0.001 0.001 
T | 0.001 0.001 0.001 0.001 0.125 0.001 0.250 0.750 0.625 0.625
Position count matrix (PCM)
A |  12  12   0   0  62   0  62  12  37  37 
C |  87  87 100 100   0  25   0  12   0   0 
G |   0   0   0   0  25  75  12   0   0   0 
T |   0   0   0   0  12   0  25  75  62  62
Position weight matrix (PWM)
A | -0.94 -0.94 -5.77 -5.77  0.67 -5.77  0.67 -0.94  0.16  0.16 
C |  1.58  1.58  1.71  1.71 -5.19  0.33 -5.19 -0.36 -5.19 -5.19 
G | -5.19 -5.19 -5.19 -5.19  0.33  1.43 -0.36 -5.19 -5.19 -5.19 
T | -5.77 -5.77 -5.77 -5.77 -0.94 -5.77 -0.25  0.85  0.67  0.67
Pachkov et al
MIG1Zhu J and MQ ZhangP = 3.54e-05View matrix ↘
Sequence logo for MIG1
Fisher’s P-value3.54e-05
Information content7.466
Max PWM score10.29
Recommended cutoff7.12
Position frequency matrix (PFM)
A | 0.07 0.07 0.07 0.07 0.50 0.07 0.50 0.14 0.36 0.29 0.36 0.29 
C | 0.79 0.79 0.79 0.79 0.07 0.43 0.07 0.21 0.07 0.07 0.07 0.21 
G | 0.07 0.07 0.07 0.07 0.36 0.43 0.21 0.07 0.07 0.07 0.07 0.07 
T | 0.07 0.07 0.07 0.07 0.07 0.07 0.21 0.57 0.50 0.57 0.50 0.43
Position count matrix (PCM)
A |   7   7   7   7  50   7  50  14  36  28  36  28 
C |  79  79  79  79   7  43   7  21   7   7   7  21 
G |   7   7   7   7  36  43  21   7   7   7   7   7 
T |   7   7   7   7   7   7  21  56  50  56  50  43
Position weight matrix (PWM)
A | -1.52 -1.52 -1.52 -1.52  0.45 -1.52  0.45 -0.83  0.12 -0.10  0.12 -0.10 
C |  1.48  1.48  1.48  1.48 -0.94  0.87 -0.94  0.15 -0.94 -0.94 -0.94  0.15 
G | -0.94 -0.94 -0.94 -0.94  0.69  0.87  0.15 -0.94 -0.94 -0.94 -0.94 -0.94 
T | -1.52 -1.52 -1.52 -1.52 -1.52 -1.52 -0.42  0.58  0.45  0.58  0.45  0.30
Zhu J and MQ Zhang
MIG1Zhu et. al.P = 2.43e-05View matrix ↘
Sequence logo for MIG1
Fisher’s P-value2.43e-05
Information content16.07
Max PWM score16.79
Recommended cutoff9.03
Position frequency matrix (PFM)
A | 0.57 0.43 0.34 0.71 0.77 0.07 0.01 0.01 0.01 0.01 0.05 0.01 0.08 0.46 0.31 0.27 0.35 
C | 0.04 0.05 0.10 0.07 0.04 0.13 0.04 0.77 0.01 0.01 0.01 0.01 0.01 0.04 0.33 0.23 0.11 
G | 0.14 0.25 0.18 0.14 0.13 0.06 0.94 0.01 0.97 0.97 0.93 0.97 0.61 0.45 0.19 0.15 0.06 
T | 0.26 0.27 0.38 0.08 0.06 0.74 0.01 0.21 0.01 0.01 0.01 0.01 0.30 0.06 0.18 0.36 0.48
Position count matrix (PCM)
A |  56  43  34  71  77   7   1   1   1   1   5   1   8  46  31  27  35 
C |   4   5  10   7   4  13   4  77   1   1   1   1   1   4  33  23  11 
G |  14  25  18  14  13   6  94   1  97  97  93  97  61  45  19  15   6 
T |  26  27  38   8   6  74   1  21   1   1   1   1  30   6  18  36  48
Position weight matrix (PWM)
A |  0.58  0.30  0.06  0.80  0.88 -1.52 -3.47 -3.47 -3.47 -3.47 -1.86 -3.47 -1.39  0.36 -0.03 -0.17  0.09 
C | -1.50 -1.28 -0.59 -0.94 -1.50 -0.33 -1.50  1.45 -2.89 -2.89 -2.89 -2.89 -2.89 -1.50  0.61  0.25 -0.49 
G | -0.25  0.33  0.00 -0.25 -0.33 -1.10  1.65 -2.89  1.68  1.68  1.64  1.68  1.22  0.92  0.05 -0.18 -1.10 
T | -0.21 -0.17  0.17 -1.39 -1.67  0.84 -3.47 -0.42 -3.47 -3.47 -3.47 -3.47 -0.06 -1.67 -0.58  0.12  0.41
Zhu et. al.
MIG1Zhao and StormoP = 0.0004727View matrix ↘
Sequence logo for MIG1
Fisher’s P-value0.0004727
Information content8.184
Max PWM score8.15
Recommended cutoff6.72
Position frequency matrix (PFM)
A | 0.162 0.100 0.009 0.012 0.261 0.140 
C | 0.234 0.444 0.001 0.001 0.001 0.001 
G | 0.491 0.063 0.976 0.986 0.737 0.767 
T | 0.113 0.394 0.014 0.001 0.001 0.092
Position count matrix (PCM)
A |  16  10   0   1  26  14 
C |  23  44   0   0   0   0 
G |  49   6  97  98  73  76 
T |  11  39   1   0   0   9
Position weight matrix (PWM)
A | -0.68 -1.16 -3.57 -3.28 -0.20 -0.83 
C |  0.26  0.90 -5.19 -5.19 -5.19 -5.19 
G |  1.00 -1.05  1.69  1.70  1.41  1.45 
T | -1.04  0.21 -3.13 -5.77 -5.77 -1.25
Zhao and Stormo
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 88 genes

YBL029W, YBL043W, YBR120C, YBR277C, YBR279W, YBR280C, YCR073C, YCR082W, YDL089W, YDL090C, YDL149W, YDL151C, YDL154W, YDL189W, YDL190C, YDL246C, YDR028C, YDR029W, YDR040C, YDR041W, YDR441C, YDR442W, YDR535C, YDR536W, YEL069C, YEL070W, YFR023W, YGL050W, YGL121C, YGL170C, YGL171W, YGR083C, YGR165W, YGR241C, YGR243W, YHR062C, YIL099W, YIL170W, YIL171W, YIL172C, YJL023C, YJL216C, YJL219W, YJL221C, YJR054W, YJR056C, YJR135C, YJR159W, YKL132C, YKL208W, YLR074C, YLR075W, YLR229C, YLR241W, YLR272C, YLR339C, YLR341W, YML124C, YMR017W, YMR019W, YMR077C, YMR163C, YMR227C, YMR228W, YMR260C, YNL126W, YNL247W, YNL248C, YOL022C, YOL063C, YOL090W, YOL105C, YOL121C, YOL156W, YOL157C, YOR109W, YOR249C, YPL180W, YPL182C, YPL200W, YPL201C, YPR114W, YPR121W, YPR136C, YPR176C, YPR178W, YPR184W, YPR198W

Genes affected by TF deletion 106 genes

YLR216C, YDR222W, YKL043W, YOR065W, YPL017C, YPL021W, YLR217W, YMR011W, YFR033C, YLR089C, YPL016W, YPL018W, YBR126C, YDR342C, YMR103C, YNR028W, YBR093C, YDR099W, YJR146W, YLL061W, YMR104C, YNL144C, YDR277C, YDR281C, YGR243W, YKL142W, YKR053C, YOR203W, YMR173W, YPL057C, YJR025C, YPL248C, YOR386W, YDR343C, YDR171W, YFL051C, YNL125C, YOL150C, YOR298W, YBR297W, YHR215W, YLR162W, YML091C, YMR291W, YBR069C, YBR071W, YBR101C, YFL052W, YOR298C-A, YPR027C, YOR221C, YAR071W, YBR296C, YER035W, YHR214W-A, YML090W, YBR050C, YHL032C, YLR234W, YML131W, YOL002C, YDR345C, YBR051W, YLR294C, YNL098C, YGR137W, YMR173W-A, YPL061W, YOR394W, YDL048C, YOR383C, YDL242W, YGL157W, YMR300C, YFL054C, YHR096C, YNL160W, YOL151W, YBR298C, YDR297W, YIL067C, YNR044W, YHR018C, YLR270W, YGR146C, YHR136C, YMR182C, YPR159W, YKR098C, YLR269C, YMR062C, YGR177C, YKL067W, YLR081W, YDL023C, YJL012C, YBL051C, YPL134C, YBR089W, YDL022W, YFL036W, YGR086C, YHR104W, YOL101C, YER079W, YML048W

Genes supported by both experiments 1 genes

YGR243W

Predicted TF–TF partners 21 genes

AFT1, AFT2, GIS1, HMS1, MET31, MIG3, MSN2, MSN4, NRG1, PDR1, PDR3, PDR8, RGM1, RGT1, RPH1, RSF2, STP1, STP2, SUT1, UME6, USV1

Explore 21 original interaction plots →