S.ScerTFYeast transcription factor database Aaron Spivak
← All factors / TF RECORD

MET31

YPL038W

View at SGD ↗

Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met32p

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Aligned Matrix
Fisher’s P-value1.12e-05
Information content12
Max PWM score10.74
Recommended cutoff9.97
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.165 0.015 0.010 0.010 0.010 0.010 0.060 0.164 
C | 0.095 0.010 0.010 0.010 0.010 0.970 0.010 0.393 
G | 0.095 0.965 0.010 0.970 0.970 0.010 0.755 0.119 
T | 0.645 0.010 0.970 0.010 0.010 0.010 0.175 0.323
Position count matrix (PCM)
A |  16   1   1   1   1   1   6  16 
C |   9   1   1   1   1  97   1  39 
G |   9  96   1  97  97   1  75  11 
T |  64   1  97   1   1   1  17  32
Position weight matrix (PWM)
A | -0.66 -3.06 -3.47 -3.47 -3.47 -3.47 -1.67 -0.67 
C | -0.64 -2.89 -2.89 -2.89 -2.89  1.68 -2.89  0.78 
G | -0.64  1.68 -2.89  1.68  1.68 -2.89  1.43 -0.41 
T |  0.70 -3.47  1.11 -3.47 -3.47 -3.47 -0.60  0.01
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 9

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

MET31Badis et. al.P = 0.001082View matrix ↘
Sequence logo for MET31
Fisher’s P-value0.001082
Information content11.27
Max PWM score9.17
Recommended cutoff9.17
Position frequency matrix (PFM)
A | 0.01 0.01 0.01 0.01 0.01 0.10 
C | 0.01 0.01 0.01 0.01 0.97 0.01 
G | 0.97 0.01 0.97 0.97 0.01 0.69 
T | 0.01 0.97 0.01 0.01 0.01 0.20
Position count matrix (PCM)
A |   1   1   1   1   1  10 
C |   1   1   1   1  97   1 
G |  97   1  97  97   1  69 
T |   1  97   1   1   1  20
Position weight matrix (PWM)
A | -3.47 -3.47 -3.47 -3.47 -3.47 -1.16 
C | -2.89 -2.89 -2.89 -2.89  1.68 -2.89 
G |  1.68 -2.89  1.68  1.68 -2.89  1.34 
T | -3.47  1.11 -3.47 -3.47 -3.47 -0.47
Badis et. al.
MET31_AFoat et. al.P = 1View matrix ↘
Sequence logo for MET31_A
Fisher’s P-value1
Information content20.29
Max PWM score22.95
Recommended cutoff17.21
Position frequency matrix (PFM)
A | 0.03 0.27 0.66 0.03 0.94 0.01 0.39 0.70 0.86 0.20 0.02 0.31 0.44 0.14 0.29 0.47 0.61 0.68 0.16 0.01 0.97 0.03 0.11 0.16 0.38 
C | 0.64 0.68 0.32 0.01 0.01 0.01 0.01 0.01 0.02 0.01 0.07 0.39 0.02 0.62 0.01 0.01 0.02 0.02 0.01 0.04 0.01 0.02 0.06 0.01 0.46 
G | 0.20 0.03 0.01 0.03 0.04 0.01 0.37 0.26 0.11 0.01 0.01 0.09 0.43 0.09 0.01 0.23 0.06 0.01 0.01 0.16 0.01 0.01 0.01 0.33 0.12 
T | 0.13 0.02 0.02 0.93 0.01 0.97 0.23 0.03 0.01 0.79 0.90 0.21 0.12 0.15 0.69 0.29 0.31 0.30 0.81 0.80 0.01 0.94 0.81 0.50 0.03
Position count matrix (PCM)
A |   3  27  66   3  94   1  39  70  86  20   2  31  44  14  28  47  61  68  16   1  97   3  11  16  38 
C |  64  68  32   1   1   1   1   1   2   1   7  39   2  62   1   1   2   2   1   4   1   2   6   1  46 
G |  20   3   1   3   4   1  37  26  11   1   1   9  43   9   1  23   6   1   1  16   1   1   1  33  12 
T |  13   2   2  93   1  97  23   3   1  79  90  21  12  15  69  28  31  30  81  80   1  94  81  50   3
Position weight matrix (PWM)
A | -2.37 -0.17  0.72 -2.37  1.08 -3.47  0.20  0.78  0.99 -0.47 -2.77 -0.03  0.32 -0.83 -0.10  0.38  0.65  0.75 -0.69 -3.47  1.11 -2.37 -1.07 -0.69  0.17 
C |  1.27  1.33  0.58 -2.89 -2.89 -2.89 -2.89 -2.89 -2.20 -2.89 -0.94  0.77 -2.20  1.24 -2.89 -2.89 -2.20 -2.20 -2.89 -1.50 -2.89 -2.20 -1.10 -2.89  0.94 
G |  0.11 -1.79 -2.89 -1.79 -1.50 -2.89  0.72  0.37 -0.49 -2.89 -2.89 -0.69  0.87 -0.69 -2.89  0.25 -1.10 -2.89 -2.89 -0.12 -2.89 -2.89 -2.89  0.61 -0.41 
T | -0.90 -2.77 -2.77  1.07 -3.47  1.11 -0.33 -2.37 -3.47  0.90  1.03 -0.42 -0.98 -0.76  0.77 -0.10 -0.03 -0.06  0.93  0.92 -3.47  1.08  0.93  0.45 -2.37
Foat et. al.
MET31_BFoat et. al.P = 0.002416View matrix ↘
Sequence logo for MET31_B
Fisher’s P-value0.002416
Information content11.45
Max PWM score14.5
Recommended cutoff10.72
Position frequency matrix (PFM)
A | 0.26 0.34 0.46 0.57 0.01 0.01 0.20 0.13 0.12 0.97 0.01 0.53 0.16 0.34 0.14 
C | 0.01 0.53 0.37 0.23 0.77 0.75 0.49 0.16 0.01 0.01 0.97 0.01 0.04 0.02 0.13 
G | 0.11 0.12 0.17 0.20 0.01 0.01 0.02 0.37 0.15 0.01 0.01 0.08 0.44 0.37 0.56 
T | 0.63 0.01 0.01 0.01 0.21 0.23 0.28 0.34 0.72 0.01 0.01 0.39 0.36 0.27 0.17
Position count matrix (PCM)
A |  26  34  46  56   1   1  20  13  12  97   1  53  16  34  14 
C |   1  53  37  23  77  75  49  16   1   1  97   1   4   2  13 
G |  11  12  17  20   1   1   2  37  15   1   1   8  44  37  56 
T |  63   1   1   1  21  23  28  34  72   1   1  39  36  27  17
Position weight matrix (PWM)
A | -0.21  0.06  0.36  0.58 -3.47 -3.47 -0.47 -0.90 -0.98  1.11 -3.47  0.50 -0.69  0.06 -0.83 
C | -2.89  1.08  0.72  0.25  1.45  1.43  1.00 -0.12 -2.89 -2.89  1.68 -2.89 -1.50 -2.20 -0.33 
G | -0.49 -0.41 -0.06  0.11 -2.89 -2.89 -2.20  0.72 -0.18 -2.89 -2.89 -0.81  0.89  0.72  1.13 
T |  0.68 -3.47 -3.47 -3.47 -0.42 -0.33 -0.13  0.06  0.81 -3.47 -3.47  0.20  0.12 -0.17 -0.63
Foat et. al.
MET31_AFordyce et. al.P = 0.0005078View matrix ↘
Fisher’s P-value0.0005078
Information content8.172
Max PWM score8.98
Recommended cutoff6.71
Position frequency matrix (PFM)
A | 0.19 0.59 0.10 0.20 0.02 0.03 0.01 0.01 
C | 0.60 0.01 0.45 0.03 0.01 0.04 0.01 0.21 
G | 0.10 0.25 0.25 0.11 0.96 0.02 0.97 0.56 
T | 0.11 0.15 0.20 0.66 0.01 0.91 0.01 0.23
Position count matrix (PCM)
A |  19  59  10  20   2   3   1   1 
C |  60   1  45   3   1   4   1  21 
G |  10  25  25  11  96   2  97  56 
T |  11  15  20  66   1  91   1  23
Position weight matrix (PWM)
A | -0.52  0.61 -1.16 -0.47 -2.77 -2.37 -3.47 -3.47 
C |  1.20 -2.89  0.92 -1.79 -2.89 -1.50 -2.89  0.15 
G | -0.59  0.33  0.33 -0.49  1.67 -2.20  1.68  1.13 
T | -1.07 -0.76 -0.47  0.72 -3.47  1.05 -3.47 -0.33
Fordyce et. al.
MET31_BFordyce et. al.P = 0.246View matrix ↘
Fisher’s P-value0.246
Information content7.932
Max PWM score9.18
Recommended cutoff5.9
Position frequency matrix (PFM)
A | 0.01 0.15 0.52 0.12 0.18 0.07 0.03 0.25 
C | 0.01 0.67 0.03 0.48 0.06 0.01 0.01 0.01 
G | 0.71 0.12 0.35 0.22 0.09 0.91 0.01 0.74 
T | 0.28 0.06 0.10 0.19 0.67 0.01 0.95 0.01
Position count matrix (PCM)
A |   1  15  52  12  18   7   3  25 
C |   1  67   3  48   6   1   1   1 
G |  71  12  35  22   9  91   1  74 
T |  28   6  10  19  67   1  95   1
Position weight matrix (PWM)
A | -3.47 -0.76  0.49 -0.98 -0.58 -1.52 -2.37 -0.25 
C | -2.89  1.31 -1.79  0.98 -1.10 -2.89 -2.89 -2.89 
G |  1.37 -0.41  0.66  0.20 -0.69  1.62 -2.89  1.41 
T | -0.13 -1.67 -1.16 -0.52  0.74 -3.47  1.09 -3.47
Fordyce et. al.
MET31_CFordyce et. al.P = 0.0003099View matrix ↘
Fisher’s P-value0.0003099
Information content8.039
Max PWM score8.94
Recommended cutoff7.53
Position frequency matrix (PFM)
A | 0.12 0.10 0.26 0.01 0.92 0.01 0.65 0.20 
C | 0.26 0.16 0.58 0.97 0.01 0.95 0.12 0.24 
G | 0.04 0.56 0.16 0.01 0.03 0.01 0.03 0.46 
T | 0.58 0.18 0.01 0.01 0.04 0.03 0.20 0.10
Position count matrix (PCM)
A |  12  10  26   1  92   1  65  20 
C |  26  16  57  97   1  95  12  24 
G |   4  56  16   1   3   1   3  46 
T |  57  18   1   1   4   3  20  10
Position weight matrix (PWM)
A | -0.98 -1.16 -0.21 -3.47  1.06 -3.47  0.71 -0.47 
C |  0.37 -0.12  1.17  1.68 -2.89  1.66 -0.41  0.29 
G | -1.50  1.13 -0.12 -2.89 -1.79 -2.89 -1.79  0.94 
T |  0.59 -0.58 -3.47 -3.47 -2.08 -2.37 -0.47 -1.16
Fordyce et. al.
MET31Harbison et. al.P = 0.02179View matrix ↘
Sequence logo for MET31
Fisher’s P-value0.02179
Information content15.64
Max PWM score12.22
Recommended cutoff7.26
Position frequency matrix (PFM)
A | 0.965 0.965 0.965 0.012 0.012 0.012 0.012 0.012 0.012 
C | 0.012 0.012 0.012 0.965 0.012 0.012 0.012 0.012 0.012 
G | 0.012 0.012 0.012 0.012 0.012 0.965 0.012 0.965 0.965 
T | 0.012 0.012 0.012 0.012 0.965 0.012 0.965 0.012 0.012
Position count matrix (PCM)
A |  96  96  96   1   1   1   1   1   1 
C |   1   1   1  96   1   1   1   1   1 
G |   1   1   1   1   1  96   1  96  96 
T |   1   1   1   1  96   1  96   1   1
Position weight matrix (PWM)
A |  1.10  1.10  1.10 -3.28 -3.28 -3.28 -3.28 -3.28 -3.28 
C | -2.71 -2.71 -2.71  1.68 -2.71 -2.71 -2.71 -2.71 -2.71 
G | -2.71 -2.71 -2.71 -2.71 -2.71  1.68 -2.71  1.68  1.68 
T | -3.28 -3.28 -3.28 -3.28  1.10 -3.28  1.10 -3.28 -3.28
Harbison et. al.
MET31Macisaac et. alP = 0.0001688View matrix ↘
Sequence logo for MET31
Fisher’s P-value0.0001688
Information content10.06
Max PWM score9.29
Recommended cutoff8.3
Position frequency matrix (PFM)
A | 0.319 0.191 0.001 0.001 0.001 0.001 0.021 0.106 
C | 0.064 0.128 0.001 0.001 0.043 0.001 0.001 0.340 
G | 0.319 0.617 0.001 0.997 0.001 0.997 0.595 0.128 
T | 0.298 0.064 0.997 0.001 0.955 0.001 0.383 0.426
Position count matrix (PCM)
A |  31  19   0   0   0   0   2  10 
C |   6  12   0   0   4   0   0  34 
G |  31  61   0  99   0  99  59  12 
T |  29   6  99   0  95   0  38  42
Position weight matrix (PWM)
A | -0.00 -0.52 -5.77 -5.77 -5.77 -5.77 -2.72 -1.10 
C | -1.03 -0.34 -5.19 -5.19 -1.43 -5.19 -5.19  0.64 
G |  0.57  1.23 -5.19  1.71 -5.19  1.71  1.20 -0.34 
T | -0.07 -1.61  1.14 -5.77  1.09 -5.77  0.18  0.29
Macisaac et. al
MET31Pachkov et alP = 0.00751View matrix ↘
Sequence logo for MET31
Fisher’s P-value0.00751
Information content15.48
Max PWM score12.35
Recommended cutoff6.28
Position frequency matrix (PFM)
A | 1.000 1.000 0.092 0.001 0.022 0.031 0.001 0.036 0.013 
C | 0.001 0.001 0.842 0.001 0.001 0.001 0.001 0.001 0.644 
G | 0.001 0.001 0.001 0.005 0.978 0.001 0.950 0.952 0.001 
T | 0.001 0.001 0.066 0.995 0.001 0.969 0.050 0.013 0.343
Position count matrix (PCM)
A | 100 100   9   0   2   3   0   3   1 
C |   0   0  84   0   0   0   0   0  64 
G |   0   0   0   0  97   0  95  95   0 
T |   0   0   6  99   0  96   5   1  34
Position weight matrix (PWM)
A |  1.14  1.14 -1.25 -5.77 -2.68 -2.33 -5.77 -2.18 -3.20 
C | -5.19 -5.19  1.54 -5.19 -5.19 -5.19 -5.19 -5.19  1.27 
G | -5.19 -5.19 -5.19 -3.58  1.69 -5.19  1.66  1.67 -5.19 
T | -5.77 -5.77 -1.58  1.13 -5.77  1.11 -1.86 -3.20  0.07
Pachkov et al
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 69 genes

YAL012W, YAR009C, YBR012W-A, YBR012W-B, YBR048W, YDL058W, YDL059C, YDL060W, YDL061C, YDL134C, YDR042C, YDR048C, YDR063W, YDR064W, YDR065W, YDR098C, YDR210W-D, YDR500C, YDR501W, YDR522C, YEL072W, YER092W, YGL030W, YGL031C, YGL134W, YGL184C, YGR084C, YGR204W, YGR221C, YHR028C, YHR193C, YHR194W, YJL060W, YJL148W, YJL191W, YJL192C, YJL210W, YJL212C, YJR100C, YJR137C, YJR138W, YLL061W, YLL062C, YLR027C, YLR035C-A, YLR043C, YLR074C, YLR075W, YLR105C, YLR166C, YLR167W, YLR179C, YLR180W, YLR368W, YML055W, YML056C, YMR014W, YMR193C-A, YMR194W, YNL025C, YNL191W, YNL277W, YNL337W, YNR050C, YOL121C, YOL139C, YPL198W, YPR167C, YPR168W

Genes affected by TF deletion 18 genes

YGR155W, YMR189W, YFL013W-A, YFR006W, YJL212C, YNL300W, YLR099C, YLR101C, YDR502C, YPL274W, YLR191W, YMR180C, YBR170C, YKL095W, YMR034C, YPL038W, YFR030W, YLR362W

Genes supported by both experiments 1 genes

YJL212C

Predicted TF–TF partners 3 genes

MIG1, RPN4, STP3

Explore 3 original interaction plots →