HSF1
YGL073W, MAS3, EXA3
Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated
Best-performing DNA-binding model.
View and copy the recommended matrices ↘
A | 0.481 0.013 0.992 0.911 0.135 0.185 0.039 0.064 0.270 0.089 0.570 0.001 0.998 0.971 0.415 C | 0.102 0.001 0.001 0.005 0.419 0.374 0.184 0.252 0.564 0.191 0.106 0.001 0.001 0.001 0.146 G | 0.417 0.987 0.008 0.054 0.150 0.261 0.089 0.002 0.137 0.013 0.323 0.999 0.001 0.029 0.227 T | 0.001 0.001 0.001 0.030 0.296 0.179 0.689 0.682 0.029 0.707 0.001 0.001 0.001 0.001 0.213
A | 48 1 99 91 13 18 3 6 27 8 56 0 99 97 41 C | 10 0 0 0 41 37 18 25 56 19 10 0 0 0 14 G | 41 98 0 5 15 26 8 0 13 1 32 99 0 2 22 T | 0 0 0 3 29 17 68 68 2 70 0 0 0 0 21
A | 0.41 -3.20 1.13 1.05 -0.86 -0.55 -2.10 -1.61 -0.17 -1.28 0.58 -5.77 1.14 1.11 0.26 C | -0.57 -5.19 -5.19 -3.58 0.84 0.73 0.02 0.34 1.14 0.06 -0.53 -5.19 -5.19 -5.19 -0.21 G | 0.84 1.70 -3.11 -1.20 -0.18 0.37 -0.70 -4.50 -0.27 -2.63 0.58 1.71 -5.19 -1.83 0.23 T | -5.77 -5.77 -5.77 -2.37 -0.08 -0.58 0.77 0.76 -2.40 0.79 -5.77 -5.77 -5.77 -5.77 -0.41
Alternative candidate matrices 7
Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.
HSF1Badis et. al.P = 9.50e-07View matrix ↘
A | 0.68 0.02 0.19 0.01 0.97 0.97 0.06 C | 0.13 0.02 0.01 0.01 0.01 0.01 0.56 G | 0.13 0.02 0.79 0.97 0.01 0.01 0.19 T | 0.06 0.94 0.01 0.01 0.01 0.01 0.19
A | 68 2 19 1 97 97 6 C | 13 2 1 1 1 1 56 G | 13 2 79 97 1 1 19 T | 6 94 1 1 1 1 19
A | 0.75 -2.77 -0.52 -3.47 1.11 1.11 -1.67 C | -0.33 -2.20 -2.89 -2.89 -2.89 -2.89 1.13 G | -0.33 -2.20 1.48 1.68 -2.89 -2.89 0.05 T | -1.67 1.08 -3.47 -3.47 -3.47 -3.47 -0.52
HSF1_AFoat et. al.P = 8.46e-32View matrix ↘
A | 0.31 0.03 0.75 0.84 0.02 0.12 0.16 0.20 0.17 0.06 0.74 0.01 0.96 0.96 0.27 0.80 0.45 C | 0.22 0.01 0.01 0.01 0.68 0.24 0.24 0.08 0.46 0.14 0.01 0.01 0.01 0.02 0.57 0.08 0.11 G | 0.46 0.95 0.23 0.02 0.29 0.62 0.12 0.20 0.32 0.01 0.25 0.97 0.02 0.01 0.02 0.12 0.05 T | 0.02 0.01 0.01 0.14 0.01 0.02 0.49 0.52 0.06 0.80 0.01 0.01 0.01 0.01 0.14 0.01 0.39
A | 31 3 75 84 2 12 16 20 17 6 74 1 96 96 27 80 45 C | 22 1 1 1 68 24 24 8 46 14 1 1 1 2 56 8 11 G | 46 95 23 2 28 62 12 20 32 1 25 97 2 1 2 12 5 T | 2 1 1 14 1 2 49 52 6 80 1 1 1 1 14 1 39
A | -0.03 -2.37 0.85 0.97 -2.77 -0.98 -0.69 -0.47 -0.63 -1.67 0.84 -3.47 1.10 1.10 -0.17 0.92 0.34 C | 0.20 -2.89 -2.89 -2.89 1.33 0.29 0.29 -0.81 0.94 -0.25 -2.89 -2.89 -2.89 -2.20 1.15 -0.81 -0.49 G | 0.94 1.66 0.25 -2.20 0.48 1.24 -0.41 0.11 0.58 -2.89 0.33 1.68 -2.20 -2.89 -2.20 -0.41 -1.28 T | -2.77 -3.47 -3.47 -0.83 -3.47 -2.77 0.43 0.49 -1.67 0.92 -3.47 -3.47 -3.47 -3.47 -0.83 -3.47 0.20
HSF1_BFoat et. al.P = 1View matrix ↘
A | 0.20 0.01 0.57 0.01 0.01 0.97 0.02 0.05 0.59 0.21 0.12 0.06 0.01 0.90 0.01 0.01 0.33 0.54 C | 0.25 0.80 0.01 0.01 0.01 0.01 0.49 0.58 0.29 0.25 0.57 0.06 0.01 0.01 0.97 0.02 0.01 0.01 G | 0.55 0.01 0.01 0.01 0.97 0.01 0.46 0.36 0.01 0.01 0.30 0.37 0.01 0.01 0.01 0.75 0.10 0.27 T | 0.01 0.18 0.42 0.97 0.01 0.01 0.04 0.01 0.10 0.53 0.01 0.51 0.97 0.08 0.01 0.22 0.57 0.19
A | 20 1 56 1 1 97 2 5 59 21 12 6 1 90 1 1 33 54 C | 25 80 1 1 1 1 49 57 28 25 56 6 1 1 97 2 1 1 G | 55 1 1 1 97 1 46 36 1 1 30 37 1 1 1 75 10 27 T | 1 18 42 97 1 1 4 1 10 53 1 51 97 8 1 22 56 19
A | -0.47 -3.47 0.58 -3.47 -3.47 1.11 -2.77 -1.86 0.61 -0.42 -0.98 -1.67 -3.47 1.03 -3.47 -3.47 0.03 0.52 C | 0.33 1.49 -2.89 -2.89 -2.89 -2.89 1.00 1.17 0.48 0.33 1.15 -1.10 -2.89 -2.89 1.68 -2.20 -2.89 -2.89 G | 1.12 -2.89 -2.89 -2.89 1.68 -2.89 0.94 0.69 -2.89 -2.89 0.51 0.72 -2.89 -2.89 -2.89 1.43 -0.59 0.41 T | -3.47 -0.58 0.27 1.11 -3.47 -3.47 -2.08 -3.47 -1.16 0.50 -3.47 0.47 1.11 -1.39 -3.47 -0.37 0.58 -0.52
HSF1_CFoat et. al.P = 1View matrix ↘
A | 0.51 0.01 0.14 0.97 0.02 0.01 0.46 0.50 0.01 0.18 0.92 0.01 0.01 0.01 0.01 0.97 0.17 0.15 C | 0.01 0.02 0.06 0.01 0.01 0.94 0.05 0.44 0.18 0.01 0.01 0.01 0.94 0.97 0.01 0.01 0.32 0.05 G | 0.01 0.45 0.76 0.01 0.01 0.01 0.11 0.02 0.57 0.63 0.01 0.36 0.01 0.01 0.01 0.01 0.28 0.79 T | 0.48 0.53 0.04 0.01 0.96 0.04 0.37 0.04 0.25 0.19 0.06 0.62 0.04 0.01 0.97 0.01 0.24 0.01
A | 51 1 14 97 2 1 46 50 1 18 92 1 1 1 1 97 17 15 C | 1 2 6 1 1 94 5 44 18 1 1 1 94 97 1 1 32 5 G | 1 45 76 1 1 1 11 2 56 63 1 36 1 1 1 1 28 79 T | 48 53 4 1 96 4 37 4 25 19 6 62 4 1 97 1 24 1
A | 0.47 -3.47 -0.83 1.11 -2.77 -3.47 0.36 0.45 -3.47 -0.58 1.06 -3.47 -3.47 -3.47 -3.47 1.11 -0.63 -0.76 C | -2.89 -2.20 -1.10 -2.89 -2.89 1.65 -1.28 0.89 0.00 -2.89 -2.89 -2.89 1.65 1.68 -2.89 -2.89 0.58 -1.28 G | -2.89 0.92 1.44 -2.89 -2.89 -2.89 -0.49 -2.20 1.15 1.25 -2.89 0.69 -2.89 -2.89 -2.89 -2.89 0.44 1.48 T | 0.41 0.50 -2.08 -3.47 1.10 -2.08 0.15 -2.08 -0.25 -0.52 -1.67 0.66 -2.08 -3.47 1.11 -3.47 -0.29 -3.47
HSF1Harbison et. al.P = 2.55e-38View matrix ↘
A | 0.073 0.009 0.031 0.100 0.565 0.173 0.425 0.441 0.215 0.290 0.073 0.034 0.046 C | 0.054 0.016 0.944 0.233 0.091 0.199 0.147 0.140 0.292 0.248 0.055 0.046 0.873 G | 0.041 0.021 0.009 0.097 0.128 0.287 0.196 0.183 0.202 0.239 0.043 0.021 0.025 T | 0.831 0.954 0.017 0.571 0.217 0.342 0.232 0.236 0.291 0.223 0.829 0.898 0.057
A | 7 0 3 10 56 17 42 44 21 28 7 3 4 C | 5 1 94 23 9 19 14 14 29 24 5 4 87 G | 4 2 0 9 12 28 19 18 20 23 4 2 2 T | 83 95 1 57 21 34 23 23 29 22 82 89 5
A | -1.48 -3.57 -2.33 -1.16 0.57 -0.62 0.28 0.32 -0.40 -0.10 -1.48 -2.24 -1.94 C | -1.20 -2.42 1.66 0.26 -0.68 0.10 -0.20 -0.25 0.48 0.32 -1.19 -1.36 1.58 G | -1.48 -2.15 -3.00 -0.62 -0.34 0.47 0.09 0.02 0.12 0.28 -1.43 -2.15 -1.97 T | 0.95 1.09 -2.94 0.58 -0.39 0.07 -0.32 -0.30 -0.09 -0.36 0.95 1.03 -1.73
HSF1Macisaac et. alP = 1.32e-35View matrix ↘
A | 0.520 0.150 0.970 0.843 0.105 0.239 0.032 0.010 0.179 0.056 0.701 0.024 0.963 0.959 C | 0.088 0.001 0.001 0.015 0.307 0.236 0.069 0.165 0.724 0.092 0.047 0.001 0.027 0.009 G | 0.371 0.813 0.010 0.079 0.209 0.294 0.064 0.052 0.045 0.039 0.243 0.949 0.001 0.009 T | 0.021 0.036 0.019 0.063 0.379 0.231 0.835 0.773 0.052 0.813 0.009 0.026 0.009 0.023
A | 52 15 97 84 10 23 3 1 17 5 70 2 96 95 C | 8 0 0 1 30 23 6 16 72 9 4 0 2 0 G | 37 81 1 7 20 29 6 5 4 3 24 94 0 0 T | 2 3 1 6 37 23 83 77 5 81 0 2 0 2
A | 0.49 -0.76 1.11 0.97 -1.11 -0.29 -2.30 -3.47 -0.58 -1.74 0.78 -2.59 1.10 1.10 C | -0.72 -5.19 -5.19 -2.48 0.53 0.27 -0.96 -0.09 1.39 -0.67 -1.34 -5.19 -1.90 -3.00 G | 0.72 1.51 -2.89 -0.82 0.15 0.49 -1.03 -1.24 -1.39 -1.53 0.30 1.66 -5.19 -3.00 T | -2.72 -2.18 -2.82 -1.63 0.17 -0.33 0.96 0.88 -1.82 0.93 -3.57 -2.51 -3.57 -2.63
HSF1Morozov et. al.P = 3.42e-28View matrix ↘
A | 0.040 0.010 0.036 0.002 0.740 0.029 0.979 0.844 C | 0.103 0.021 0.939 0.002 0.059 0.033 0.013 0.057 G | 0.047 0.025 0.021 0.003 0.178 0.733 0.006 0.045 T | 0.810 0.944 0.004 0.994 0.023 0.204 0.002 0.054
A | 4 1 3 0 74 2 97 84 C | 10 2 93 0 5 3 1 5 G | 4 2 2 0 17 73 0 4 T | 81 94 0 99 2 20 0 5
A | -2.08 -3.47 -2.18 -5.08 0.84 -2.40 1.12 0.97 C | -0.56 -2.15 1.65 -4.50 -1.12 -1.70 -2.63 -1.15 G | -1.34 -1.97 -2.15 -4.09 -0.01 1.40 -3.40 -1.39 T | 0.93 1.08 -4.38 1.13 -2.63 -0.45 -5.08 -1.78
Gene-level annotations and interactions.
Genes bound in ChIP-chip experiments 96 genes
YBL076C, YBR021W, YBR101C, YBR109C, YBR110W, YBR216C, YBR217W, YBR256C, YBR257W, YBR280C, YBR293W, YCL002C, YCL006C, YCL007C, YCL008C, YCL009C, YCL010C, YCL040W, YCL042W, YCL044C, YCL059C, YCL065W, YCL066W, YCL067C, YCR002C, YCR004C, YCR005C, YCR006C, YCR008W, YCR012W, YCR030C, YCR083W, YDL073W, YDL074C, YDL092W, YDL094C, YDL176W, YDL177C, YDL227C, YDL230W, YDL231C, YDL240W, YDR048C, YDR056C, YDR057W, YDR084C, YDR113C, YDR115W, YDR164C, YDR165W, YDR258C, YDR361C, YDR387C, YDR388W, YDR396W, YEL033W, YEL034W, YEL035C, YER035W, YER122C, YER123W, YER137C-A, YGL095C, YGL195W, YGR161C, YGR220C, YHR173C, YHR174W, YIL048W, YJL001W, YJL002C, YJR043C, YJR154W, YKL039W, YKL040C, YKL123W, YKL124W, YKR051W, YLL006W, YLL007C, YLL032C, YLL035W, YLL036C, YLL038C, YMR161W, YMR186W, YMR260C, YOL042W, YOL043C, YOL137W, YOL138C, YOR005C, YOR020C, YOR027W, YOR102W, YPR122W
Genes affected by TF deletion 620 genes
YBR034C, YBR006W, YCL050C, YCR012W, YDR034C-C, YDR064W, YER145C, YER118C, YGL171W, YGL234W, YGL173C, YHL016C, YIL078W, YIL116W, YIL148W, YJR016C, YJR054W, YLR244C, YLR216C, YMR041C, YML116W, YMR046W-A, YOL012C, YOR192C-A, YOR225W, YOR259C, YPL237W, YPL207W, YPL211W, YBR187W, YBR158W, YBR189W, YBR160W, YBR191W, YBR162C, YDL128W, YDL130W, YDR222W, YEL012W, YEL042W, YEL046C, YGR121C, YHR143W, YHR174W, YJL049W, YKL043W, YKL049C, YLR025W, YLR058C, YLR029C, YLR062C, YLR094C, YLR432W, YLR406C, YNL239W, YNL209W, YNL277W, YOR071C, YPL019C, YBR001C, YBR031W, YBL087C, YBR003W, YBR005W, YBR035C, YCL049C, YCR013C, YDR397C, YDR399W, YER117W, YGL166W, YHL011C, YHL043W, YHL015W, YJR015W, YJR079W, YLR275W, YLR217W, YLR249W, YMR009W, YML115C, YOL011W, YOL014W, YOR226C, YOR258W, YPL240C, YAL038W, YBR157C, YDL061C, YDL095W, YDL129W, YEL017C-A, YGL008C, YGL012W, YGR090W, YGR094W, YGR123C, YJL052W, YJL086C, YKL110C, YLR089C, YLR061W, YLR405W, YMR191W, YNL208W, YNL274C, YPR138C, YBR126C, YDR050C, YBR068C, YDL037C, YDR158W, YDR462W, YFR005C, YHR053C, YHR055C, YJR145C, YJR147W, YKL016C, YJR149W, YLR338W, YLR340W, YLR372W, YMR105C, YNL149C, YOR289W, YPR052C, YPL283C, YBL027W, YBR251W, YBR283C, YER055C, YER056C-A, YER086W, YGL103W, YGL135W, YGL077C, YGR214W, YHR208W, YIL018W, YIL052C, YJL177W, YML029W, YMR284W, YMR316W, YNL301C, YNL333W, YBR093C, YBR067C, YDR461W, YGR004W, YGR034W, YIR031C, YLL061W, YLR304C, YLR367W, YLR339C, YMR131C, YNL142W, YNL146W, YPL265W, YPR013C, YBL024W, YBL026W, YBR282W, YBR252W, YBR286W, YDR275W, YDR281C, YER025W, YER056C, YER057C, YGL102C, YGR211W, YGR185C, YIL015W, YHR209W, YIL019W, YIL051C, YJL148W, YJL212C, YKL138C, YLR119W, YLR153C, YML022W, YML024W, YML026C, YMR315W, YNL300W, YNL332W, YNL302C, YOR132W, YPL079W, YPL111W, YPL143W, YPL081W, YPL145C, YER042W, YBR010W, YBR012C, YCR021C, YDR012W, YDR072C, YGL238W, YHR001W-A, YIL154C, YJR094W-A, YKR081C, YLR286C, YLR227W-A, YLR287C-A, YML123C, YMR022W, YNL030W, YNR067C, YOL052C-A, YAL044C, YAR015W, YBR167C, YDL136W, YDR224C, YEL050C, YGL047W, YFR042W, YGR160W, YGR132C, YGR161W-A, YHR152W, YHR154W, YKL056C, YLR068W, YLR441C, YNL217W, YNL281W, YNL283C, YNL284C-A, YOR077W, YOR047C, YPL057C, YBL092W, YBR009C, YDR405W, YER124C, YHL021C, YIL117C, YIL119C, YIL121W, YIL123W, YJR027W, YLR225C, YLR285W, YMR023C, YNL054W-A, YNL055C, YOR234C, YPL249C-A, YJR148W, YAL040C, YDL103C, YDL075W, YDR225W, YGL016W, YGR159C, YHR126C, YKL081W, YKL112W, YKL055C, YLR069C, YLR410W-A, YDR134C, YDR508C, YHR089C, YJR124C, YLR344W, YMR145C, YOL086C, YPR010C, YBL003C, YDL228C, YER036C, YGL147C, YGR254W, YGR192C, YHR215W, YJL217W, YJL159W, YJL191W, YKL180W, YLR130C, YPL118W, YPL090C, YFL031W, YCR087C-A, YDR170W-A, YHR060W, YHR094C, YJR123W, YLL039C, YMR108W, YMR110C, YMR142C, YPL273W, YAR071W, YAR075W, YBL002W, YBL032W, YCL025C, YBR296C, YDL229W, YDL201W, YER035W, YER062C, YGL078C, YGR219W, YGR191W, YGR255C, YIL053W, YHR216W, YJL152W, YJL184W, YJL158C, YJL190C, YKL150W, YKL181W, YLR163C, YML063W, YMR292W, YNL310C, YBR016W, YDR382W, YDR418W, YDR450W, YER131W, YGL189C, YHL026C, YHR010W, YIL094C, YIL098C, YIL130W, YJR070C, YKR057W, YKR059W, YLR259C, YLR264W, YNL067W, YNL069C, YOL058W, YOL031C, YOL002C, YPL225W, YDL082W, YDL084W, YGL055W, YGR109W-B, YJL067W, YKL096W, YLR104W, YLR076C, YMR174C, YMR242C, YPL035C, YPL037C, YEL054C, YBL101W-A, YER159C-A, YFL002C, YGL245W, YHL001W, YIL157C, YLR233C, YNL031C, YNL066W, YOR204W, YOR208W, YPL220W, YMR008C, YBR202W, YDL081C, YDL083C, YGL028C, YGR165W, YHR128W, YJL098W, YJL068C, YKL120W, YLR075W, YLR413W, YLR448W, YMR205C, YPL061W, YPL032C, YBR078W, YBR084C-A, YDL048C, YFL026W, YGR019W, YKL030W, YKL001C, YKL032C, YLR352W, YLR388W, YMR120C, YOL120C, YOR335C, YBL072C, YCL034W, YDL172C, YDR296W, YER070W, YGL123W, YGL157W, YGR260W, YLR204W, YPL128C, YFL032W, YBR143C, YDL014W, YCR096C, YDR111C, YDR174W, YFL056C, YGR074W, YGR044C, YGR080W, YHR038W, YHR070W, YHR072W, YJL037W, YKL029C, YLL045C, YLR014C, YLR351C, YLR355C, YLR325C, YMR116C, YMR121C, YNL160W, YNL162W, YOL119C, YOL151W, YOL121C, YOR304W, YPR061C, YPR002C-A, YPR035W, YPR067W, YBL005W-A, YBL038W, YBL042C, YCL035C, YCL037C, YDL173W, YDR321W, YDR322W, YDR358W, YER044C, YGL120C, YGR259C, YJL196C, YJL198W, YKL152C, YKL218C, YKL156W, YLR197W, YLR167W, YLR201C, YML040W, YML073C, YNL005C, YPL093W, YPL131W, YPL163C, YER091C, YBR054W, YBR024W, YBR028C, YCR034W, YGL225W, YHL040C, YHR020W, YIL170W, YIL140W, YLR270W, YMR006C, YNL073W, YNL109W, YOL039W, YOL070C, YOR277C, YOR247W, YPL197C, YEL027W, YAL060W, YAR042W, YAL062W, YBR181C, YBR185C, YDL124W, YDR214W, YFR056C, YGL031C, YGR148C, YGR176W, YHR136C, YHR170W, YHR141C, YJL077C, YJL079C, YKL068W, YKL133C, YKL103C, YLR048W, YLR112W, YLR118C, YLR426W, YMR184W, YMR186W, YOR063W, YOR095C, YBL107W-A, YBR059C, YCR003W, YCR031C, YCR005C, YDR055W, YDR453C, YFL002W-B, YER165W, YFL004W, YGL253W, YGL255W, YGL226C-A, YHL033C, YHR019C, YIL133C, YIL171W, YJR045C, YJR077C, YLR267W, YLR300W, YMR062C, YMR007W, YMR038C, YOL009C, YOL040C, YOL071W, YOR278W, YOR248W, YOR280C, YPL198W, YKL009W, YAL028W, YEL064C, YFR055W, YGL030W, YGL032C, YGR118W, YGR177C, YHR203C, YJL136C, YJL138C, YJL078C, YKL069W, YKL100C, YLR452C, YLR423C, YML018C, YMR243C, YMR215W, YMR217W, YMR250W, YNL268W, YOR024W, YOR026W, YPR107C, YDR120C, YFL034C-A, YFR030W, YFR031C-A, YHR046C, YHR048W, YHR078W, YHR049W, YJL012C, YKL006W, YKL008C, YLL024C, YLL026W, YOR369C, YOR375C, YPR040W, YPR044C, YCL040W, YCL042W, YDL182W, YDR365W-A, YER110C, YGR240C, YIL009W, YLR178C, YLR150W, YLR180W, YNL327W, YPL136W, YPL106C, YDR119W, YHR047C, YOL101C, YBL016W, YER073W, YER102W, YJL200C, YKL163W, YLR205C, YLR175W, YLR179C, YNL007C, YOR182C, YPL107W, YER061C
Genes supported by both experiments 7 genes
YCL040W, YCL042W, YCR005C, YCR012W, YER035W, YHR174W, YMR186W
Predicted TF–TF partners 3 genes
ABF1, EDS1, XBP1