← All factors / TF RECORD
HAP3
YBL021C
Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding
01 / RECOMMENDED MATRIX
Best-performing DNA-binding model.
Fisher’s P-value3.35e-12
Information content15.03
Max PWM score14.7
Recommended cutoff9.34
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.005 0.120 0.005 0.032 0.984 0.005 0.005 0.005 0.005 0.005 0.032 0.260 0.489 0.359 C | 0.181 0.675 0.161 0.304 0.005 0.005 0.005 0.005 0.005 0.484 0.400 0.379 0.089 0.089 G | 0.190 0.098 0.005 0.502 0.005 0.005 0.005 0.984 0.984 0.005 0.140 0.332 0.309 0.442 T | 0.624 0.107 0.828 0.163 0.005 0.984 0.984 0.005 0.005 0.505 0.429 0.030 0.112 0.111
Position count matrix (PCM)
A | 0 12 0 3 98 0 0 0 0 0 3 26 48 35 C | 18 67 16 30 0 0 0 0 0 48 40 37 8 8 G | 19 9 0 50 0 0 0 98 98 0 14 33 30 44 T | 62 10 82 16 0 98 98 0 0 50 42 3 11 11
Position weight matrix (PWM)
A | -4.16 -0.98 -4.16 -2.30 1.12 -4.16 -4.16 -4.16 -4.16 -4.16 -2.30 -0.21 0.42 0.12 C | 0.01 1.32 -0.11 0.52 -3.58 -3.58 -3.58 -3.58 -3.58 0.99 0.80 0.74 -0.70 -0.70 G | 0.05 -0.61 -3.58 1.03 -3.58 -3.58 -3.58 1.70 1.70 -3.58 -0.25 0.61 0.54 0.90 T | 0.67 -1.10 0.95 -0.67 -4.16 1.12 1.12 -4.16 -4.16 0.46 0.29 -2.37 -1.05 -1.06
02 / COMPARATIVE BENCHMARKS
Alternative candidate matrices 5
Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.
HAP3Foat et. al.P = 0.000562View matrix ↘
Fisher’s P-value0.000562
Information content15.83
Max PWM score18.21
Recommended cutoff9.39
Position frequency matrix (PFM)
A | 0.02 0.01 0.05 0.83 0.96 0.05 0.07 0.38 0.22 0.77 0.59 0.01 0.16 0.01 0.92 0.10 0.25 0.01 C | 0.12 0.85 0.06 0.16 0.02 0.50 0.17 0.01 0.01 0.05 0.27 0.23 0.01 0.94 0.07 0.02 0.50 0.01 G | 0.49 0.04 0.01 0.01 0.01 0.17 0.14 0.33 0.24 0.01 0.01 0.49 0.80 0.01 0.01 0.61 0.02 0.19 T | 0.38 0.11 0.88 0.01 0.01 0.28 0.62 0.28 0.52 0.17 0.13 0.27 0.03 0.04 0.01 0.27 0.24 0.78
Position count matrix (PCM)
A | 2 1 5 83 96 5 7 38 22 77 59 1 16 1 92 10 25 1 C | 12 85 6 16 2 50 17 1 1 5 27 23 1 94 7 2 50 1 G | 49 4 1 1 1 17 14 33 24 1 1 49 80 1 1 61 2 19 T | 38 11 88 1 1 28 62 28 52 17 13 27 3 4 1 27 24 78
Position weight matrix (PWM)
A | -2.77 -3.47 -1.86 0.95 1.10 -1.86 -1.52 0.17 -0.37 0.88 0.61 -3.47 -0.69 -3.47 1.06 -1.16 -0.25 -3.47 C | -0.41 1.55 -1.10 -0.12 -2.20 1.02 -0.06 -2.89 -2.89 -1.28 0.41 0.25 -2.89 1.65 -0.94 -2.20 1.02 -2.89 G | 1.00 -1.50 -2.89 -2.89 -2.89 -0.06 -0.25 0.61 0.29 -2.89 -2.89 1.00 1.49 -2.89 -2.89 1.22 -2.20 0.05 T | 0.17 -1.07 1.01 -3.47 -3.47 -0.13 0.66 -0.13 0.49 -0.63 -0.90 -0.17 -2.37 -2.08 -3.47 -0.17 -0.29 0.89
HAP3Harbison et. al.P = 0.002188View matrix ↘
Fisher’s P-value0.002188
Information content8.513
Max PWM score6.66
Recommended cutoff6.66
Position frequency matrix (PFM)
A | 0.012 0.012 0.965 0.965 0.012 C | 0.965 0.965 0.012 0.012 0.012 G | 0.012 0.012 0.012 0.012 0.012 T | 0.012 0.012 0.012 0.012 0.965
Position count matrix (PCM)
A | 1 1 96 96 1 C | 96 96 1 1 1 G | 1 1 1 1 1 T | 1 1 1 1 96
Position weight matrix (PWM)
A | -3.28 -3.28 1.10 1.10 -3.28 C | 1.68 1.68 -2.71 -2.71 -2.71 G | -2.71 -2.71 -2.71 -2.71 -2.71 T | -3.28 -3.28 -3.28 -3.28 1.10
HAP3Macisaac et. alP = 0.002188View matrix ↘
Fisher’s P-value0.002188
Information content8.496
Max PWM score6.66
Recommended cutoff6.66
Position frequency matrix (PFM)
A | 0.012 0.012 0.964 0.964 0.012 C | 0.964 0.964 0.012 0.012 0.012 G | 0.012 0.012 0.012 0.012 0.012 T | 0.012 0.012 0.012 0.012 0.964
Position count matrix (PCM)
A | 1 1 96 96 1 C | 96 96 1 1 1 G | 1 1 1 1 1 T | 1 1 1 1 96
Position weight matrix (PWM)
A | -3.28 -3.28 1.10 1.10 -3.28 C | 1.68 1.68 -2.71 -2.71 -2.71 G | -2.71 -2.71 -2.71 -2.71 -2.71 T | -3.28 -3.28 -3.28 -3.28 1.10
HAP3_APachkov et alP = 0.008391View matrix ↘
Fisher’s P-value0.008391
Information content14.45
Max PWM score11.72
Recommended cutoff10.32
Position frequency matrix (PFM)
A | 0.001 0.060 1.000 0.001 0.001 0.001 0.001 0.034 0.051 C | 0.001 0.006 0.001 0.001 0.001 0.001 0.001 0.443 0.637 G | 0.001 0.934 0.001 0.001 0.001 1.000 0.927 0.079 0.035 T | 1.000 0.001 0.001 0.999 0.999 0.001 0.073 0.445 0.277
Position count matrix (PCM)
A | 0 6 100 0 0 0 0 3 5 C | 0 0 0 0 0 0 0 44 63 G | 0 93 0 0 0 100 92 7 3 T | 100 0 0 99 99 0 7 44 27
Position weight matrix (PWM)
A | -5.77 -1.67 1.14 -5.77 -5.77 -5.77 -5.77 -2.24 -1.84 C | -5.19 -3.40 -5.19 -5.19 -5.19 -5.19 -5.19 0.90 1.26 G | -5.19 1.65 -5.19 -5.19 -5.19 1.71 1.64 -0.82 -1.64 T | 1.14 -5.77 -5.77 1.14 1.14 -5.77 -1.48 0.33 -0.14
HAP3_BPachkov et alP = 1.92e-11View matrix ↘
Fisher’s P-value1.92e-11
Information content15.88
Max PWM score15.24
Recommended cutoff9.18
Position frequency matrix (PFM)
A | 0.001 0.121 0.001 0.033 1.000 0.001 0.001 0.001 0.001 0.001 0.033 0.259 0.489 0.357 0.503 C | 0.182 0.676 0.162 0.304 0.001 0.001 0.001 0.001 0.001 0.489 0.399 0.377 0.089 0.087 0.191 G | 0.190 0.097 0.001 0.499 0.001 0.001 0.001 1.000 1.000 0.001 0.139 0.333 0.308 0.444 0.094 T | 0.628 0.106 0.838 0.164 0.001 1.000 1.000 0.001 0.001 0.511 0.429 0.031 0.114 0.111 0.211
Position count matrix (PCM)
A | 0 12 0 3 100 0 0 0 0 0 3 25 48 35 50 C | 18 67 16 30 0 0 0 0 0 48 39 37 8 8 19 G | 19 9 0 49 0 0 0 100 100 0 13 33 30 44 9 T | 62 10 83 16 0 100 100 0 0 51 42 3 11 11 21
Position weight matrix (PWM)
A | -5.77 -0.97 -5.77 -2.27 1.14 -5.77 -5.77 -5.77 -5.77 -5.77 -2.27 -0.21 0.42 0.11 0.45 C | 0.01 1.32 -0.11 0.52 -5.19 -5.19 -5.19 -5.19 -5.19 1.00 0.80 0.74 -0.70 -0.73 0.06 G | 0.05 -0.62 -5.19 1.02 -5.19 -5.19 -5.19 1.71 1.71 -5.19 -0.26 0.62 0.54 0.90 -0.65 T | 0.67 -1.10 0.96 -0.67 -5.77 1.14 1.14 -5.77 -5.77 0.47 0.29 -2.33 -1.03 -1.06 -0.42
03 / EXPERIMENTAL CONTEXT
Gene-level annotations and interactions.
Genes bound in ChIP-chip experiments 81 genes
YBR039W, YBR216C, YBR217W, YCR028C, YDL045C, YDL170W, YDL171C, YDR030C, YDR031W, YDR084C, YDR130C, YDR146C, YDR147W, YDR282C, YDR292C, YDR372C, YDR373W, YDR377W, YDR503C, YEL004W, YEL005C, YER049W, YER174C, YER175C, YER176W, YER183C, YFR023W, YGL133W, YGL187C, YGL191W, YGL193C, YGL195W, YGR084C, YGR187C, YGR191W, YGR234W, YHR001W-A, YHR028C, YHR044C, YHR045W, YHR051W, YJL023C, YJL060W, YJL096W, YJL097W, YJL145W, YJL148W, YJR077C, YJR078W, YJR079W, YJR082C, YJR100C, YKL039W, YKL040C, YKL072W, YKR103W, YLL027W, YLR211C, YLR220W, YML077W, YML119W, YML120C, YMR065W, YMR125W, YMR126C, YMR258C, YNL009W, YNL232W, YNR006W, YNR054C, YOL023W, YOL105C, YOR106W, YOR112W, YOR138C, YOR140W, YOR258W, YPL207W, YPR158W-A, YPR158W-B, YPR197C
Genes affected by TF deletion 30 genes
YCR016W, YMR220W, YPL053C, YHR179W, YPL016W, YBR093C, YCL018W, YDR281C, YDR442W, YJR148W, YDR506C, YHR215W, YFL014W, YGL214W, YKL120W, YER072W, YER040W, YIL067C, YKL218C, YHR136C, YLR269C, YBR244W, YBR248C, YEL037C, YHR135C, YNL292W, YDL060W, YOR374W, YCL006C, YGL094C