← All factors / TF RECORD
HAC1
YFL031W, IRE15, ERN4
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis
01 / RECOMMENDED MATRIX
Best-performing DNA-binding model.
Fisher’s P-value7.56e-16
Information content14.93
Max PWM score12.53
Recommended cutoff10.07
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.794 0.091 0.152 0.544 0.001 0.958 0.001 0.001 0.152 0.895 C | 0.001 0.001 0.001 0.411 0.997 0.001 0.997 0.001 0.001 0.001 G | 0.001 0.495 0.846 0.001 0.001 0.001 0.001 0.997 0.001 0.001 T | 0.204 0.414 0.001 0.044 0.001 0.040 0.001 0.001 0.846 0.103
Position count matrix (PCM)
A | 79 9 15 54 0 95 0 0 15 89 C | 0 0 0 41 99 0 99 0 0 0 G | 0 49 84 0 0 0 0 99 0 0 T | 20 41 0 4 0 4 0 0 84 10
Position weight matrix (PWM)
A | 0.91 -1.26 -0.74 0.53 -5.77 1.10 -5.77 -5.77 -0.74 1.03 C | -5.19 -5.19 -5.19 0.83 1.71 -5.19 1.71 -5.19 -5.19 -5.19 G | -5.19 1.01 1.55 -5.19 -5.19 -5.19 -5.19 1.71 -5.19 -5.19 T | -0.45 0.26 -5.77 -1.98 -5.77 -2.08 -5.77 -5.77 0.97 -1.13
02 / COMPARATIVE BENCHMARKS
Alternative candidate matrices 4
Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.
HAC1Badis et. al.P = 6.71e-07View matrix ↘
Fisher’s P-value6.71e-07
Information content10.88
Max PWM score9.12
Recommended cutoff7.71
Position frequency matrix (PFM)
A | 0.24 0.67 0.01 0.97 0.01 0.01 0.01 C | 0.06 0.31 0.97 0.01 0.97 0.01 0.01 G | 0.55 0.01 0.01 0.01 0.01 0.97 0.01 T | 0.15 0.01 0.01 0.01 0.01 0.01 0.97
Position count matrix (PCM)
A | 24 67 1 97 1 1 1 C | 6 31 97 1 97 1 1 G | 55 1 1 1 1 97 1 T | 15 1 1 1 1 1 97
Position weight matrix (PWM)
A | -0.29 0.74 -3.47 1.11 -3.47 -3.47 -3.47 C | -1.10 0.54 1.68 -2.89 1.68 -2.89 -2.89 G | 1.12 -2.89 -2.89 -2.89 -2.89 1.68 -2.89 T | -0.76 -3.47 -3.47 -3.47 -3.47 -3.47 1.11
HAC1Foat et. al.P = 2.82e-12View matrix ↘
Fisher’s P-value2.82e-12
Information content11.59
Max PWM score11.93
Recommended cutoff9.55
Position frequency matrix (PFM)
A | 0.52 0.20 0.10 0.73 0.03 0.96 0.01 0.07 0.09 0.56 0.09 C | 0.05 0.06 0.01 0.24 0.91 0.01 0.96 0.06 0.09 0.12 0.28 G | 0.14 0.55 0.88 0.01 0.01 0.01 0.01 0.86 0.10 0.25 0.06 T | 0.30 0.20 0.01 0.02 0.05 0.02 0.02 0.01 0.73 0.06 0.57
Position count matrix (PCM)
A | 52 20 10 73 3 96 1 7 9 56 9 C | 5 6 1 24 91 1 96 6 9 12 28 G | 14 55 88 1 1 1 1 86 10 25 6 T | 30 20 1 2 5 2 2 1 73 6 56
Position weight matrix (PWM)
A | 0.49 -0.47 -1.16 0.82 -2.37 1.10 -3.47 -1.52 -1.27 0.56 -1.27 C | -1.28 -1.10 -2.89 0.29 1.62 -2.89 1.67 -1.10 -0.69 -0.41 0.44 G | -0.25 1.12 1.59 -2.89 -2.89 -2.89 -2.89 1.56 -0.59 0.33 -1.10 T | -0.06 -0.47 -3.47 -2.77 -1.86 -2.77 -2.77 -3.47 0.82 -1.67 0.58
HAC1Harbison et. al.P = 0.002528View matrix ↘
Fisher’s P-value0.002528
Information content21.16
Max PWM score17.06
Recommended cutoff16.48
Position frequency matrix (PFM)
A | 0.012 0.012 0.488 0.012 0.965 0.012 0.012 0.012 0.012 0.012 0.012 0.012 C | 0.012 0.012 0.488 0.964 0.012 0.012 0.964 0.012 0.012 0.012 0.012 0.964 G | 0.488 0.964 0.012 0.012 0.012 0.964 0.012 0.964 0.012 0.964 0.012 0.012 T | 0.488 0.012 0.012 0.012 0.012 0.012 0.012 0.012 0.965 0.012 0.965 0.012
Position count matrix (PCM)
A | 1 1 48 1 96 1 1 1 1 1 1 1 C | 1 1 48 96 1 1 96 1 1 1 1 96 G | 48 96 1 1 1 96 1 96 1 96 1 1 T | 48 1 1 1 1 1 1 1 96 1 96 1
Position weight matrix (PWM)
A | -3.28 -3.28 0.42 -3.28 1.10 -3.28 -3.28 -3.28 -3.28 -3.28 -3.28 -3.28 C | -2.71 -2.71 1.00 1.68 -2.71 -2.71 1.68 -2.71 -2.71 -2.71 -2.71 1.68 G | 1.00 1.68 -2.71 -2.71 -2.71 1.68 -2.71 1.68 -2.71 1.68 -2.71 -2.71 T | 0.42 -3.28 -3.28 -3.28 -3.28 -3.28 -3.28 -3.28 1.10 -3.28 1.10 -3.28
HAC1Morozov et. al.P = 0.04993View matrix ↘
Fisher’s P-value0.04993
Information content5.995
Max PWM score8.73
Recommended cutoff5.38
Position frequency matrix (PFM)
A | 0.036 0.220 0.136 0.071 0.125 0.089 0.076 0.526 C | 0.040 0.136 0.087 0.811 0.107 0.165 0.682 0.307 G | 0.122 0.432 0.679 0.069 0.733 0.412 0.076 0.067 T | 0.802 0.212 0.098 0.049 0.036 0.334 0.167 0.100
Position count matrix (PCM)
A | 3 22 13 7 12 8 7 52 C | 4 13 8 81 10 16 68 30 G | 12 43 67 6 73 41 7 6 T | 80 21 9 4 3 33 16 10
Position weight matrix (PWM)
A | -2.18 -0.37 -0.86 -1.51 -0.94 -1.28 -1.44 0.50 C | -1.50 -0.28 -0.73 1.51 -0.52 -0.09 1.33 0.53 G | -0.39 0.88 1.33 -0.96 1.40 0.83 -0.86 -0.99 T | 0.92 -0.41 -1.18 -1.88 -2.18 0.04 -0.65 -1.16
03 / EXPERIMENTAL CONTEXT
Gene-level annotations and interactions.
Genes bound in ChIP-chip experiments 49 genes
YBL025W, YBR012W-A, YBR012W-B, YBR099C, YBR213W, YCR018C-A, YCR019W, YCR033W, YDL069C, YDL118W, YDL146W, YDR040C, YDR041W, YDR042C, YDR084C, YDR210W-D, YDR217C, YDR540C, YER007C-A, YER129W, YER138C, YFR007W, YFR026C, YFR041C, YFR042W, YGL214W, YGR161W-A, YGR161W-B, YHR044C, YHR045W, YIL048W, YIL139C, YJL034W, YJL035C, YJL175W, YKL071W, YKL165C, YKL177W, YKL179C, YKR061W, YLR404W, YMR178W, YNL044W, YOL023W, YOL030W, YOL031C, YOL115W, YOR058C, YOR143C
Genes affected by TF deletion 16 genes
YBL097W, YDR215C, YFL013W-A, YBR093C, YDR281C, YLR312W-A, YFL031W, YBR105C, YKL214C, YGR164W, YGR168C, YGR111W, YHR132C, YPR068C, YFL032W, YMR034C
Predicted TF–TF partners 2 genes
PHO4, SWI6