S.ScerTFYeast transcription factor database Aaron Spivak
← All factors / TF RECORD

GTS1

YGL181W, LSR1, FHT1

View at SGD ↗

Arf3p GTPase Activating Protein (GAP) that localizes to endocytic patches; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms; localizes to nucleus and induces flocculation when overexpressed

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Macisaac et. al
Fisher’s P-value0.000502
Information content8.81
Max PWM score7.3
Recommended cutoff7.3
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.150 0.997 0.001 0.001 0.836 0.988 
C | 0.001 0.001 0.734 0.975 0.009 0.001 
G | 0.001 0.001 0.036 0.001 0.154 0.010 
T | 0.848 0.001 0.229 0.023 0.001 0.001
Position count matrix (PCM)
A |  15  99   0   0  83  98 
C |   0   0  73  97   0   0 
G |   0   0   3   0  15   1 
T |  84   0  22   2   0   0
Position weight matrix (PWM)
A | -0.76  1.14 -5.77 -5.77  0.96  1.13 
C | -5.19 -5.19  1.41  1.69 -3.00 -5.19 
G | -5.19 -5.19 -1.61 -5.19 -0.16 -2.89 
T |  0.97 -5.77 -0.33 -2.63 -5.77 -5.77
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 1

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

GTS1Foat et. al.P = 1View matrix ↘
Sequence logo for GTS1
Fisher’s P-value1
Information content19.28
Max PWM score21.8
Recommended cutoff16.35
Position frequency matrix (PFM)
A | 0.04 0.18 0.97 0.01 0.01 0.14 0.02 0.30 0.03 0.59 0.33 0.07 0.42 0.02 0.27 0.36 0.06 0.14 0.01 0.01 0.32 0.32 0.03 
C | 0.27 0.22 0.01 0.01 0.01 0.13 0.01 0.27 0.06 0.01 0.04 0.07 0.08 0.32 0.32 0.09 0.09 0.01 0.97 0.97 0.01 0.40 0.51 
G | 0.61 0.04 0.01 0.97 0.01 0.58 0.67 0.41 0.45 0.33 0.25 0.02 0.12 0.50 0.24 0.46 0.24 0.01 0.01 0.01 0.25 0.07 0.31 
T | 0.08 0.57 0.01 0.01 0.97 0.14 0.30 0.02 0.46 0.07 0.38 0.85 0.38 0.16 0.17 0.10 0.61 0.84 0.01 0.01 0.43 0.21 0.15
Position count matrix (PCM)
A |   4  18  97   1   1  14   2  30   3  59  33   7  42   2  27  36   6  14   1   1  32  32   3 
C |  27  22   1   1   1  13   1  27   6   1   4   7   8  32  32   9   9   1  97  97   1  40  51 
G |  61   4   1  97   1  57  67  41  45  33  25   2  12  50  24  46  24   1   1   1  25   7  31 
T |   8  56   1   1  97  14  30   2  46   7  38  85  38  16  17  10  61  84   1   1  43  21  15
Position weight matrix (PWM)
A | -2.08 -0.58  1.11 -3.47 -3.47 -0.83 -2.77 -0.06 -2.37  0.61  0.03 -1.52  0.27 -2.77 -0.17  0.12 -1.67 -0.83 -3.47 -3.47  0.00  0.00 -2.37 
C |  0.41  0.20 -2.89 -2.89 -2.89 -0.33 -2.89  0.41 -1.10 -2.89 -1.50 -0.94 -0.81  0.58  0.58 -0.69 -0.69 -2.89  1.68  1.68 -2.89  0.80  1.04 
G |  1.22 -1.50 -2.89  1.68 -2.89  1.17  1.31  0.82  0.92  0.61  0.33 -2.20 -0.41  1.02  0.29  0.94  0.29 -2.89 -2.89 -2.89  0.33 -0.94  0.54 
T | -1.39  0.58 -3.47 -3.47  1.11 -0.83 -0.06 -2.77  0.36 -1.52  0.17  0.98  0.17 -0.69 -0.63 -1.16  0.65  0.97 -3.47 -3.47  0.30 -0.42 -0.76
Foat et. al.
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 102 genes

YAL022C, YAL064C-A, YAL065C, YAL067C, YAL068C, YBR060C, YBR099C, YBR159W, YBR201W, YBR273C, YBR274W, YCR018C-A, YCR019W, YDL098C, YDL179W, YDR093W, YDR094W, YDR223W, YDR226W, YDR282C, YDR284C, YDR285W, YDR366C, YDR368W, YDR372C, YDR373W, YDR507C, YDR509W, YEL018W, YEL019C, YEL037C, YEL055C, YER138C, YER164W, YER166W, YFL011W, YFR001W, YFR021W, YFR023W, YFR036W, YFR037C, YFR038W, YFR039C, YFR040W, YFR044C, YFR045W, YGL240W, YGL241W, YGL242C, YGL245W, YGL246C, YGR017W, YGR027C, YGR033C, YGR034W, YGR038C-B, YGR084C, YGR090W, YGR126W, YGR290W, YHL034C, YHR077C, YHR078W, YHR079C, YHR138C, YKL004W, YKL005C, YKL006C-A, YKL006W, YKL033W, YLL043W, YLL045C, YLR035C-A, YLR346C, YLR428C, YLR430W, YMR067C, YMR068W, YMR118C, YMR166C, YMR167W, YNL025C, YNL111C, YNL167C, YNR034W-A, YNR074C, YNR075W, YOL041C, YOL086C, YOL088C, YOL127W, YOL128C, YOL129W, YOR192C, YOR290C, YOR291W, YPL018W, YPL019C, YPR004C, YPR048W, YPR049C, YPR051W

Genes affected by TF deletion 195 genes

YDR064W, YIL148W, YJR085C, YJR054W, YNR061C, YPL211W, YLR106C, YMR109W, YDL130W, YGL013C, YLR467W, YMR192W, YNL243W, YBL112C, YDR034C-A, YDR034C-D, YDR365W-B, YER140W, YGL168W, YGL172W, YGL204C, YIL082W, YIL113W, YKR009C, YKR040C, YLR217W, YMR009W, YML117W, YMR046C, YNL021W, YOR254C, YOR192C-B, YOR256C, YPL240C, YMR266W, YDL061C, YHR145C, YLR466W, YPL016W, YOL142W, YPR052C, YPL283C, YGL071W, YLR152C, YNL301C, YNL339C, YPL142C, YPL084W, YBR093C, YCR081W, YDR526C, YDR465C, YGR028W, YGR034W, YLR304C, YLR367W, YOR086C, YBR252W, YDR281C, YER057C, YLR183C, YML022W, YML084W, YML058W, YGR296W, YHL050C, YIL156W, YJR094W-A, YOL051W, YAL044C, YAL046C, YJL121C, YKL056C, YLR098C, YMR202W, YOR043W, YPL059W, YOR262W, YOR234C, YPL246C, YPL218W, YLR035C-A, YLR437C, YOR390W, YDR134C, YLR344W, YOR142W-A, YDL038C, YDL040C, YFL050C, YLR345W, YNL118C, YOR326W, YPR053C, YPR055W, YMR292W, YNR001C, YGL062W, YCR024C-A, YDR418W, YLR259C, YLR230W, YLR264W, YNL069C, YOL002C, YEL026W, YKL058W, YLR110C, YBL101W-A, YDR417C, YHL001W, YJR063W, YLR229C, YML130C, YMR058W, YNL037C, YPL220W, YPL251W, YDL081C, YDL083C, YDL145C, YHR128W, YLR073C, YLR043C, YMR237W, YPL061W, YHR072W-A, YJL034W, YJL004C, YKL033W-A, YOL120C, YOL092W, YER072W, YHR219W, YPL094C, YPL098C, YOL119C, YPR063C, YER044C, YJL160C, YLR201C, YNR046W, YOL008W, YOL039W, YOR251C, YEL027W, YNL201C, YEL065W, YHR136C, YMR186W, YOR027W, YPL041C, YCR028C-A, YCR031C, YFL002W-B, YGL255W, YIL133C, YMR034C, YNL070W, YNL043C, YOL040C, YPL257W-B, YPL234C, YBR210W, YDR210W-A, YGL030W, YGR143W, YHR135C, YOR090C, YPL075W, YPR158W-B, YDR122W, YFL067W, YGR027C, YIR022W, YKL006W, YLR017W, YNL135C, YOR343C-B, YPR044C, YBL051C, YCL040W, YIL040W, YIL011W, YLR146C, YFL068W, YMR123W, YOL101C, YOR370C, YOR343C-A, YOR374W, YPR037C, YGR203W, YIL069C, YKR001C

Genes supported by both experiments 4 genes

YGR027C, YGR034W, YKL006W, YLR035C-A