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FZF1

YGL254W, SUL1, RSU1, NRC299

View at SGD ↗

Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Badis et. al.
Fisher’s P-value0.6524
Information content10.1
Max PWM score7.8
Recommended cutoff7.8
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.01 0.01 0.97 0.01 0.01 0.97 
C | 0.97 0.01 0.01 0.01 0.97 0.01 
G | 0.01 0.01 0.01 0.01 0.01 0.01 
T | 0.01 0.97 0.01 0.97 0.01 0.01 
Position count matrix (PCM)
A |   1   1  97   1   1  97 
C |  97   1   1   1  97   1 
G |   1   1   1   1   1   1 
T |   1  97   1  97   1   1 
Position weight matrix (PWM)
A | -3.47 -3.47  1.11 -3.47 -3.47  1.11 
C |  1.68 -2.89 -2.89 -2.89  1.68 -2.89 
G | -2.89 -2.89 -2.89 -2.89 -2.89 -2.89 
T | -3.47  1.11 -3.47  1.11 -3.47 -3.47 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 1

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

FZF1Foat et. al.P = 1View matrix ↘
Sequence logo for FZF1
Fisher’s P-value1
Information content19.47
Max PWM score18.77
Recommended cutoff14.08
Position frequency matrix (PFM)
A | 0.01 0.03 0.01 0.89 0.03 0.97 0.02 0.07 0.68 0.01 0.01 0.97 0.01 0.75 0.28 0.09 0.42 
C | 0.23 0.46 0.55 0.01 0.94 0.01 0.79 0.82 0.01 0.39 0.01 0.01 0.97 0.01 0.01 0.16 0.55 
G | 0.09 0.01 0.04 0.09 0.02 0.01 0.17 0.11 0.31 0.59 0.26 0.01 0.01 0.24 0.10 0.50 0.01 
T | 0.67 0.51 0.40 0.01 0.01 0.01 0.02 0.01 0.01 0.01 0.72 0.01 0.01 0.01 0.62 0.25 0.01 
Position count matrix (PCM)
A |   1   3   1  89   3  97   2   7  68   1   1  97   1  75  28   9  42 
C |  23  46  55   1  94   1  79  82   1  39   1   1  97   1   1  16  55 
G |   9   1   4   9   2   1  17  11  31  59  26   1   1  24  10  50   1 
T |  67  51  40   1   1   1   2   1   1   1  72   1   1   1  62  25   1 
Position weight matrix (PWM)
A | -3.47 -2.37 -3.47  1.02 -2.37  1.11 -2.77 -1.52  0.75 -3.47 -3.47  1.11 -3.47  0.85 -0.13 -1.27  0.27 
C |  0.25  0.94  1.12 -2.89  1.65 -2.89  1.48  1.52 -2.89  0.77 -2.89 -2.89  1.68 -2.89 -2.89 -0.12  1.12 
G | -0.69 -2.89 -1.50 -0.69 -2.20 -2.89 -0.06 -0.49  0.54  1.19  0.37 -2.89 -2.89  0.29 -0.59  1.02 -2.89 
T |  0.74  0.47  0.22 -3.47 -3.47 -3.47 -2.77 -3.47 -3.47 -3.47  0.81 -3.47 -3.47 -3.47  0.66 -0.25 -3.47 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 97 genes

YAL017W, YAL018C, YAL022C, YBL001C, YBR012C, YBR013C, YBR040W, YBR154C, YBR155W, YBR160W, YBR178W, YBR188C, YBR189W, YCL039W, YCL041C, YCL043C, YDL045W-A, YDL089W, YDL090C, YDL104C, YDL108W, YDL109C, YDL202W, YDL203C, YDL206W, YDR042C, YDR064W, YDR098C, YDR179C, YDR179W-A, YDR245W, YDR318W, YDR319C, YDR468C, YDR469W, YDR484W, YDR526C, YEL001C, YEL030W, YER049W, YER083C, YFR017C, YGL202W, YGR089W, YGR128C, YGR129W, YGR156W, YGR218W, YHR085W, YHR089C, YHR138C, YIL147C, YIR023W, YJL148W, YJR011C, YJR044C, YJR100C, YLR061W, YLR076C, YLR077W, YLR105C, YLR229C, YLR277C, YLR367W, YLR368W, YLR409C, YLR410W, YMR125W, YMR131C, YMR218C, YMR219W, YMR227C, YMR228W, YMR238W, YMR257C, YMR270C, YNL146W, YNR018W, YOR004W, YOR070C, YOR109W, YOR110W, YOR138C, YOR140W, YOR141C, YOR142W, YOR273C, YOR274W, YPL018W, YPL019C, YPL034W, YPL123C, YPL179W, YPL216W, YPL217C, YPL251W, YPL253C

Genes affected by TF deletion 29 genes

YIL082W-A, YHR146W, YMR220W, YBR093C, YBR129C, YER029C, YOR229W, YOR073W, YOR075W, YGL212W, YNL090W, YOR074C, YMR145C, YPL092W, YPL156C, YMR144W, YNL154C, YOL149W, YNL065W, YOL029C, YNL289W, YGL254W, YLR297W, YOR029W, YMR034C, YBR244W, YLR049C, YDR122W, YOL101C

Predicted TF–TF partners 1 genes

SPT23

Explore 1 original interaction plots →