S.ScerTFYeast transcription factor database Aaron Spivak
← All factors / TF RECORD

DIG1

YPL049C, RST1

View at SGD ↗

Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Foat et. al.
Fisher’s P-value6.92e-17
Information content9.914
Max PWM score8.83
Recommended cutoff8.02
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.51 0.59 0.02 0.96 0.97 0.01 0.01 0.01 
C | 0.01 0.08 0.01 0.02 0.01 0.01 0.01 0.42 
G | 0.43 0.32 0.96 0.01 0.01 0.01 0.83 0.08 
T | 0.06 0.01 0.01 0.01 0.01 0.97 0.15 0.50
Position count matrix (PCM)
A |  51  59   2  96  97   1   1   1 
C |   1   8   1   2   1   1   1  42 
G |  43  32  96   1   1   1  83   8 
T |   6   1   1   1   1  97  15  50
Position weight matrix (PWM)
A |  0.47  0.61 -2.77  1.10  1.11 -3.47 -3.47 -3.47 
C | -2.89 -0.81 -2.89 -2.20 -2.89 -2.89 -2.89  0.85 
G |  0.87  0.58  1.67 -2.89 -2.89 -2.89  1.53 -0.81 
T | -1.67 -3.47 -3.47 -3.47 -3.47  1.11 -0.76  0.45
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 8

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

DIG1_AFoat et. al.P = 1View matrix ↘
Sequence logo for DIG1_A
Fisher’s P-value1
Information content16.87
Max PWM score18.92
Recommended cutoff14.19
Position frequency matrix (PFM)
A | 0.01 0.95 0.02 0.02 0.44 0.36 0.36 0.75 0.17 0.13 0.24 0.18 0.28 0.16 0.01 0.02 0.01 0.09 0.27 0.79 
C | 0.20 0.01 0.96 0.01 0.28 0.47 0.07 0.14 0.23 0.17 0.01 0.59 0.03 0.05 0.11 0.01 0.02 0.24 0.26 0.08 
G | 0.24 0.03 0.01 0.01 0.04 0.07 0.16 0.03 0.56 0.57 0.34 0.23 0.21 0.17 0.87 0.01 0.96 0.03 0.44 0.09 
T | 0.55 0.01 0.01 0.96 0.24 0.10 0.41 0.09 0.05 0.12 0.42 0.01 0.48 0.62 0.01 0.97 0.01 0.64 0.03 0.03
Position count matrix (PCM)
A |   1  95   2   2  44  36  36  75  17  13  24  18  28  16   1   2   1   9  27  79 
C |  20   1  96   1  28  47   7  14  23  17   1  59   3   5  11   1   2  24  26   8 
G |  24   3   1   1   4   7  16   3  56  56  34  23  21  17  87   1  96   3  44   9 
T |  55   1   1  96  24  10  41   9   5  12  42   1  48  62   1  97   1  64   3   3
Position weight matrix (PWM)
A | -3.47  1.09 -2.77 -2.77  0.32  0.12  0.12  0.85 -0.63 -0.90 -0.29 -0.58 -0.13 -0.69 -3.47 -2.77 -3.47 -1.27 -0.17  0.90 
C |  0.11 -2.89  1.67 -2.89  0.44  0.96 -0.94 -0.25  0.25 -0.06 -2.89  1.19 -1.79 -1.28 -0.49 -2.89 -2.20  0.29  0.37 -0.81 
G |  0.29 -1.79 -2.89 -2.89 -1.50 -0.94 -0.12 -1.79  1.13  1.15  0.64  0.25  0.15 -0.06  1.58 -2.89  1.67 -1.79  0.89 -0.69 
T |  0.54 -3.47 -3.47  1.10 -0.29 -1.16  0.25 -1.27 -1.86 -0.98  0.27 -3.47  0.41  0.66 -3.47  1.11 -3.47  0.69 -2.37 -2.37
Foat et. al.
DIG1_BFoat et. al.P = 1View matrix ↘
Sequence logo for DIG1_B
Fisher’s P-value1
Information content21.48
Max PWM score24.82
Recommended cutoff18.61
Position frequency matrix (PFM)
A | 0.41 0.17 0.84 0.01 0.01 0.84 0.03 0.44 0.21 0.20 0.34 0.26 0.21 0.38 0.08 0.59 0.07 0.11 0.30 0.02 0.01 0.82 0.01 0.18 0.03 
C | 0.49 0.11 0.10 0.01 0.97 0.04 0.62 0.04 0.46 0.51 0.01 0.55 0.35 0.31 0.62 0.12 0.65 0.01 0.30 0.43 0.97 0.01 0.02 0.13 0.32 
G | 0.01 0.02 0.01 0.02 0.01 0.08 0.14 0.40 0.27 0.29 0.21 0.01 0.01 0.17 0.21 0.01 0.27 0.01 0.01 0.51 0.01 0.01 0.96 0.01 0.45 
T | 0.09 0.69 0.05 0.96 0.01 0.04 0.21 0.12 0.06 0.01 0.45 0.19 0.43 0.14 0.10 0.29 0.01 0.88 0.39 0.04 0.01 0.16 0.01 0.68 0.20
Position count matrix (PCM)
A |  41  17  84   1   1  84   3  44  21  20  34  26  21  38   8  59   7  11  30   2   1  82   1  18   3 
C |  49  11  10   1  97   4  62   4  46  51   1  55  35  31  62  12  65   1  30  43  97   1   2  13  32 
G |   1   2   1   2   1   8  14  40  27  28  21   1   1  17  21   1  27   1   1  51   1   1  96   1  45 
T |   9  69   5  96   1   4  21  12   6   1  45  19  43  14  10  28   1  88  39   4   1  16   1  68  20
Position weight matrix (PWM)
A |  0.25 -0.63  0.97 -3.47 -3.47  0.97 -2.37  0.32 -0.42 -0.47  0.06 -0.21 -0.42  0.17 -1.39  0.61 -1.52 -1.07 -0.06 -2.77 -3.47  0.94 -3.47 -0.58 -2.37 
C |  1.00 -0.49 -0.59 -2.89  1.68 -1.50  1.24 -1.50  0.94  1.04 -2.89  1.12  0.66  0.54  1.24 -0.41  1.28 -2.89  0.51  0.87  1.68 -2.89 -2.20 -0.33  0.58 
G | -2.89 -2.20 -2.89 -2.20 -2.89 -0.81 -0.25  0.80  0.41  0.48  0.15 -2.89 -2.89 -0.06  0.15 -2.89  0.41 -2.89 -2.89  1.04 -2.89 -2.89  1.67 -2.89  0.92 
T | -1.27  0.77 -1.86  1.10 -3.47 -2.08 -0.42 -0.98 -1.67 -3.47  0.34 -0.52  0.30 -0.83 -1.16 -0.10 -3.47  1.01  0.20 -2.08 -3.47 -0.69 -3.47  0.75 -0.47
Foat et. al.
DIG1_CFoat et. al.P = 1View matrix ↘
Sequence logo for DIG1_C
Fisher’s P-value1
Information content17.27
Max PWM score15.16
Recommended cutoff11.37
Position frequency matrix (PFM)
A | 0.01 0.01 0.57 0.87 0.78 0.01 0.40 0.01 0.01 0.01 0.01 0.66 0.94 0.01 
C | 0.36 0.49 0.01 0.10 0.18 0.01 0.01 0.61 0.04 0.97 0.01 0.07 0.04 0.02 
G | 0.53 0.50 0.35 0.02 0.01 0.01 0.24 0.01 0.94 0.01 0.01 0.27 0.01 0.94 
T | 0.10 0.01 0.07 0.01 0.03 0.97 0.35 0.38 0.01 0.01 0.97 0.01 0.01 0.03
Position count matrix (PCM)
A |   1   1  56  87  78   1  40   1   1   1   1  66  94   1 
C |  36  49   1  10  18   1   1  61   4  97   1   7   4   2 
G |  53  50  35   2   1   1  24   1  94   1   1  27   1  94 
T |  10   1   7   1   3  97  35  38   1   1  97   1   1   3
Position weight matrix (PWM)
A | -3.47 -3.47  0.58  1.00  0.89 -3.47  0.22 -3.47 -3.47 -3.47 -3.47  0.72  1.08 -3.47 
C |  0.69  1.00 -2.89 -0.59  0.00 -2.89 -2.89  1.22 -1.50  1.68 -2.89 -0.94 -1.50 -2.20 
G |  1.08  1.02  0.66 -2.20 -2.89 -2.89  0.29 -2.89  1.65 -2.89 -2.89  0.41 -2.89  1.65 
T | -1.16 -3.47 -1.52 -3.47 -2.37  1.11  0.09  0.17 -3.47 -3.47  1.11 -3.47 -3.47 -2.37
Foat et. al.
DIG1_DFoat et. al.P = 0.0001805View matrix ↘
Sequence logo for DIG1_D
Fisher’s P-value0.0001805
Information content19.88
Max PWM score19
Recommended cutoff9.93
Position frequency matrix (PFM)
A | 0.01 0.52 0.01 0.97 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.94 0.29 0.20 0.28 
C | 0.07 0.25 0.41 0.01 0.97 0.97 0.04 0.16 0.79 0.10 0.01 0.97 0.01 0.39 0.40 0.70 
G | 0.48 0.01 0.54 0.01 0.01 0.01 0.01 0.81 0.01 0.60 0.11 0.01 0.03 0.01 0.32 0.01 
T | 0.44 0.23 0.05 0.01 0.01 0.01 0.94 0.02 0.19 0.30 0.88 0.01 0.02 0.31 0.08 0.01
Position count matrix (PCM)
A |   1  52   1  97   1   1   1   1   1   1   1   1  94  28  20  28 
C |   7  25  41   1  97  97   4  16  79  10   1  97   1  39  40  70 
G |  48   1  54   1   1   1   1  81   1  60  11   1   3   1  32   1 
T |  44  23   5   1   1   1  94   2  19  30  88   1   2  31   8   1
Position weight matrix (PWM)
A | -3.47  0.49 -3.47  1.11 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47 -3.47  1.08 -0.10 -0.47 -0.13 
C | -0.94  0.33  0.82 -2.89  1.68  1.68 -1.50 -0.12  1.48 -0.59 -2.89  1.68 -2.89  0.77  0.80  1.36 
G |  0.98 -2.89  1.10 -2.89 -2.89 -2.89 -2.89  1.50 -2.89  1.20 -0.49 -2.89 -1.79 -2.89  0.58 -2.89 
T |  0.32 -0.33 -1.86 -3.47 -3.47 -3.47  1.08 -2.77 -0.52 -0.06  1.01 -3.47 -2.77 -0.03 -1.39 -3.47
Foat et. al.
DIG1_EFoat et. al.P = 3.24e-08View matrix ↘
Sequence logo for DIG1_E
Fisher’s P-value3.24e-08
Information content15.13
Max PWM score14.04
Recommended cutoff9.98
Position frequency matrix (PFM)
A | 0.04 0.08 0.01 0.02 0.03 0.01 0.18 0.01 0.97 0.01 0.68 0.07 
C | 0.17 0.06 0.22 0.01 0.13 0.01 0.01 0.97 0.01 0.19 0.29 0.56 
G | 0.78 0.03 0.01 0.96 0.01 0.01 0.01 0.01 0.01 0.74 0.01 0.01 
T | 0.01 0.83 0.77 0.01 0.83 0.97 0.81 0.01 0.01 0.06 0.03 0.37
Position count matrix (PCM)
A |   4   8   1   2   3   1  18   1  97   1  68   7 
C |  17   6  22   1  13   1   1  97   1  19  28  56 
G |  78   3   1  96   1   1   1   1   1  74   1   1 
T |   1  83  77   1  83  97  81   1   1   6   3  37
Position weight matrix (PWM)
A | -2.08 -1.39 -3.47 -2.77 -2.37 -3.47 -0.58 -3.47  1.11 -3.47  0.75 -1.52 
C | -0.06 -1.10  0.20 -2.89 -0.33 -2.89 -2.89  1.68 -2.89  0.05  0.48  1.13 
G |  1.47 -1.79 -2.89  1.67 -2.89 -2.89 -2.89 -2.89 -2.89  1.41 -2.89 -2.89 
T | -3.47  0.95  0.88 -3.47  0.95  1.11  0.93 -3.47 -3.47 -1.67 -2.37  0.15
Foat et. al.
DIG1_GFoat et. al.P = 0.00169View matrix ↘
Sequence logo for DIG1_G
Fisher’s P-value0.00169
Information content18.94
Max PWM score16.89
Recommended cutoff10.49
Position frequency matrix (PFM)
A | 0.49 0.83 0.01 0.01 0.01 0.01 0.01 0.46 0.01 0.01 0.01 0.14 0.16 0.91 
C | 0.05 0.16 0.01 0.96 0.97 0.01 0.28 0.15 0.97 0.10 0.97 0.49 0.01 0.06 
G | 0.21 0.01 0.97 0.01 0.01 0.97 0.21 0.34 0.01 0.41 0.01 0.26 0.79 0.01 
T | 0.25 0.01 0.02 0.02 0.01 0.01 0.50 0.05 0.01 0.49 0.01 0.11 0.04 0.02
Position count matrix (PCM)
A |  49  83   1   1   1   1   1  46   1   1   1  14  16  91 
C |   5  16   1  96  97   1  28  15  97  10  97  49   1   6 
G |  21   1  97   1   1  97  21  34   1  41   1  26  79   1 
T |  25   1   2   2   1   1  50   5   1  49   1  11   4   2
Position weight matrix (PWM)
A |  0.43  0.95 -3.47 -3.47 -3.47 -3.47 -3.47  0.36 -3.47 -3.47 -3.47 -0.83 -0.69  1.05 
C | -1.28 -0.12 -2.89  1.67  1.68 -2.89  0.44 -0.18  1.68 -0.59  1.68  1.00 -2.89 -1.10 
G |  0.15 -2.89  1.68 -2.89 -2.89  1.68  0.15  0.64 -2.89  0.82 -2.89  0.37  1.48 -2.89 
T | -0.25 -3.47 -2.77 -2.77 -3.47 -3.47  0.45 -1.86 -3.47  0.43 -3.47 -1.07 -2.08 -2.77
Foat et. al.
DIG1Harbison et. al.P = 4.42e-15View matrix ↘
Sequence logo for DIG1
Fisher’s P-value4.42e-15
Information content7.323
Max PWM score7.86
Recommended cutoff5.99
Position frequency matrix (PFM)
A | 0.127 0.152 0.911 0.872 0.871 0.071 0.755 
C | 0.033 0.036 0.036 0.016 0.031 0.822 0.042 
G | 0.008 0.793 0.010 0.057 0.050 0.059 0.126 
T | 0.831 0.020 0.043 0.055 0.048 0.049 0.077
Position count matrix (PCM)
A |  12  15  91  87  87   7  75 
C |   3   3   3   1   3  82   4 
G |   0  79   1   5   5   5  12 
T |  83   2   4   5   4   4   7
Position weight matrix (PWM)
A | -0.92 -0.74  1.05  1.00  1.00 -1.51  0.86 
C | -1.70 -1.61 -1.61 -2.42 -1.76  1.52 -1.46 
G | -3.11  1.48 -2.89 -1.15 -1.28 -1.12 -0.36 
T |  0.95 -2.77 -2.01 -1.76 -1.90 -1.88 -1.42
Harbison et. al.
DIG1Macisaac et. alP = 1View matrix ↘
Sequence logo for DIG1
Fisher’s P-value1
Information content7.73
Max PWM score11.04
Recommended cutoff10.47
Position frequency matrix (PFM)
A | 0.488 0.399 0.506 0.220 0.534 0.383 0.289 0.244 0.397 0.147 0.074 0.921 0.859 0.916 0.134 0.533 
C | 0.145 0.219 0.129 0.481 0.121 0.188 0.147 0.181 0.221 0.051 0.052 0.001 0.019 0.022 0.797 0.116 
G | 0.156 0.141 0.161 0.095 0.167 0.144 0.147 0.095 0.150 0.146 0.863 0.006 0.042 0.035 0.017 0.160 
T | 0.211 0.242 0.204 0.204 0.178 0.284 0.417 0.479 0.233 0.656 0.011 0.072 0.080 0.027 0.052 0.191
Position count matrix (PCM)
A |  48  39  50  22  53  38  28  24  39  14   7  92  85  91  13  53 
C |  14  21  12  48  12  18  14  18  22   5   5   0   1   2  79  11 
G |  15  14  16   9  16  14  14   9  15  14  86   0   4   3   1  16 
T |  21  24  20  20  17  28  41  47  23  65   1   7   8   2   5  19
Position weight matrix (PWM)
A |  0.42  0.22  0.46 -0.37  0.51  0.18 -0.10 -0.27  0.22 -0.78 -1.46  1.06  0.99  1.05 -0.87  0.51 
C | -0.22  0.20 -0.33  0.98 -0.40  0.04 -0.20  0.01  0.21 -1.26 -1.24 -5.19 -2.25 -2.10  1.49 -0.44 
G | -0.14 -0.24 -0.11 -0.64 -0.07 -0.22 -0.20 -0.64 -0.18 -0.21  1.57 -3.40 -1.46 -1.64 -2.36 -0.12 
T | -0.42 -0.28 -0.45 -0.45 -0.59 -0.12  0.26  0.40 -0.32  0.72 -3.37 -1.49 -1.39 -2.47 -1.82 -0.52
Macisaac et. al
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 110 genes

YAL002W, YAR009C, YAR027W, YBL004W, YBL016W, YBL017C, YBL023C, YBR083W, YBR084W, YCL019W, YCL020W, YCL022C, YCL023C, YCL027W, YCL055W, YCL056C, YCR017C, YCR026C, YCR089W, YDL127W, YDR042C, YDR085C, YDR210W-D, YDR211W, YDR240C, YDR307W, YDR316W-A, YDR316W-B, YDR386W, YDR461W, YEL012W, YEL027W, YER138C, YER159C-A, YER160C, YFL039C, YFR023W, YGL032C, YGL062W, YGL134W, YGR013W, YGR014W, YGR038C-A, YGR038C-B, YGR162W, YGR165W, YGR189C, YGR256W, YHR005C, YHR072W, YHR072W-A, YHR082C, YHR083W, YHR084W, YHR086W, YIL015W, YIL036W, YIL037C, YIL082W, YIL083C, YIL095W, YIL123W, YIL169C, YJL148W, YJL186W, YJL187C, YKL095W, YKL189W, YKR091W, YLR035C-A, YLR105C, YLR344W, YLR452C, YML124C, YMR013C, YMR014W, YMR052C-A, YMR052W, YMR053C, YMR054W, YMR065W, YMR119W, YMR119W-A, YMR197C, YMR198W, YMR232W, YNL032W, YNL034W, YNL043C, YNL145W, YNL279W, YNL280C, YNR028W, YOL103W, YOR086C, YOR236W, YOR343C, YPL130W, YPL156C, YPL192C, YPL198W, YPL257W-A, YPL257W-B, YPR002C-A, YPR036W, YPR060C, YPR135W, YPR158W-A, YPR158W-B, YPR198W

Genes affected by TF deletion 121 genes

YCL055W, YLR216C, YOL045W, YMR226C, YPL049C, YNL078W, YMR189W, YOR066W, YPL016W, YPL048W, YKL016C, YOL104C, YAR064W, YAR068W, YDR339C, YER028C, YLR154C, YBR093C, YBR129C, YDR461W, YDR530C, YMR072W, YNL146W, YOL139C, YOL109W, YOR086C, YER029C, YGL106W, YIL015W, YBR010W, YHR005C, YJR060W, YML119W, YNL058C, YNL030W, YOR203W, YBR009C, YLR285W, YNL057W, YOR202W, YDL075W, YDR225W, YMR171C, YOR074C, YBR132C, YJR153W, YPR060C, YBL003C, YHR214W, YHR215W, YLR192C, YMR260C, YMR294W-A, YPL156C, YGR040W, YMR112C, YOL149W, YOR298C-A, YPL273W, YAR071W, YCL027W, YHR214W-A, YML063W, YML094W, YML095C-A, YMR321C, YNL312W, YPL117C, YPR199C, YKR093W, YNL065W, YLR231C, YLR292C, YLR294C, YNL031C, YOL032W, YDR209C, YGR137W, YOR052C, YBR082C, YFL026W, YGR019W, YGR234W, YMR304C-A, YBR083W, YDR481C, YFL027C, YBL042C, YGR195W, YNR044W, YPL129W, YHR018C, YNL107W, YNL109W, YMR034C, YNL108C, YOR212W, YGL032C, YHR201C, YLR079W, YLR049C, YLR452C, YNL266W, YPL038W, YPL071C, YBR087W, YBR090C, YCR099C, YDR486C, YDR524C, YGR085C, YNL205C, YIL044C, YIL076W, YLR210W, YMR305C, YGR024C, YOL159C, YOL133W, YOR342C, YIL009C-A

Genes supported by both experiments 11 genes

YBR083W, YCL027W, YCL055W, YDR461W, YGL032C, YHR005C, YIL015W, YLR452C, YOR086C, YPL156C, YPR060C