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CEP3

YMR168C, CSL1, CBF3B, CBF3

View at SGD ↗

Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Zhu et. al.
Fisher’s P-valueNo data
Information content13.79
Max PWM score18.61
Recommended cutoff13.95
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.09 0.24 0.23 0.13 0.41 0.11 0.03 0.01 0.01 0.01 0.01 0.78 0.89 0.66 0.21 0.35 0.12 0.20 0.42 0.17 
C | 0.18 0.15 0.43 0.31 0.15 0.57 0.37 0.03 0.96 0.28 0.01 0.04 0.01 0.14 0.32 0.28 0.16 0.16 0.11 0.13 
G | 0.58 0.48 0.06 0.48 0.21 0.17 0.09 0.01 0.02 0.70 0.97 0.14 0.03 0.10 0.11 0.15 0.19 0.43 0.30 0.57 
T | 0.15 0.13 0.27 0.08 0.23 0.15 0.52 0.95 0.01 0.01 0.01 0.03 0.07 0.10 0.36 0.23 0.53 0.20 0.17 0.13 
Position count matrix (PCM)
A |   9  24  23  13  41  11   3   1   1   1   1  78  89  66  21  35  12  20  42  17 
C |  18  15  43  31  15  56  37   3  96  28   1   4   1  14  32  28  16  16  11  13 
G |  57  48   6  48  21  17   9   1   2  70  97  14   3  10  11  15  19  43  30  56 
T |  15  13  27   8  23  15  52  95   1   1   1   3   7  10  36  23  53  20  17  13 
Position weight matrix (PWM)
A | -1.27 -0.29 -0.33 -0.90  0.25 -1.07 -2.37 -3.47 -3.47 -3.47 -3.47  0.89  1.02  0.72 -0.42  0.09 -0.98 -0.47  0.27 -0.63 
C |  0.00 -0.18  0.87  0.54 -0.18  1.15  0.72 -1.79  1.67  0.44 -2.89 -1.50 -2.89 -0.25  0.58  0.44 -0.12 -0.12 -0.49 -0.33 
G |  1.17  0.98 -1.10  0.98  0.15 -0.06 -0.69 -2.89 -2.20  1.36  1.68 -0.25 -1.79 -0.59 -0.49 -0.18  0.05  0.87  0.51  1.15 
T | -0.76 -0.90 -0.17 -1.39 -0.33 -0.76  0.49  1.09 -3.47 -3.47 -3.47 -2.37 -1.52 -1.16  0.12 -0.33  0.50 -0.47 -0.63 -0.90 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 2

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

CEP3Badis et. al.P = No dataView matrix ↘
Sequence logo for CEP3
Fisher’s P-valueNo data
Information content11.09
Max PWM score9.38
Recommended cutoff7.04
Position frequency matrix (PFM)
A | 0.04 0.01 0.01 0.01 0.01 0.91 0.91 
C | 0.56 0.01 0.97 0.01 0.01 0.01 0.03 
G | 0.04 0.01 0.01 0.97 0.97 0.01 0.03 
T | 0.36 0.97 0.01 0.01 0.01 0.07 0.03 
Position count matrix (PCM)
A |   4   1   1   1   1  91  91 
C |  56   1  97   1   1   1   3 
G |   4   1   1  97  97   1   3 
T |  36  97   1   1   1   7   3 
Position weight matrix (PWM)
A | -2.08 -3.47 -3.47 -3.47 -3.47  1.05  1.05 
C |  1.13 -2.89  1.68 -2.89 -2.89 -2.89 -1.79 
G | -1.50 -2.89 -2.89  1.68  1.68 -2.89 -1.79 
T |  0.12  1.11 -3.47 -3.47 -3.47 -1.52 -2.37 
CEP3Zhao and StormoP = No dataView matrix ↘
Sequence logo for CEP3
Fisher’s P-valueNo data
Information content3.95
Max PWM score6.3
Recommended cutoff4.72
Position frequency matrix (PFM)
A | 0.018 0.001 0.200 0.144 0.243 0.222 0.197 0.220 
C | 0.793 0.027 0.145 0.318 0.318 0.285 0.292 0.288 
G | 0.009 0.005 0.516 0.355 0.203 0.220 0.225 0.238 
T | 0.180 0.967 0.139 0.182 0.236 0.274 0.286 0.255 
Position count matrix (PCM)
A |   1   0  20  14  24  22  19  22 
C |  79   2  14  31  31  28  29  28 
G |   0   0  51  35  20  22  22  23 
T |  18  96  13  18  23  27  28  25 
Position weight matrix (PWM)
A | -2.88 -5.77 -0.47 -0.80 -0.28 -0.37 -0.49 -0.37 
C |  1.48 -1.90 -0.22  0.57  0.57  0.46  0.48  0.47 
G | -3.00 -3.58  1.05  0.68  0.12  0.20  0.22  0.28 
T | -0.58  1.11 -0.83 -0.56 -0.30 -0.16 -0.11 -0.23 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 1 genes

No Data

Genes affected by TF deletion 1 genes

No Data

Genes supported by both experiments 1 genes

No Data

Predicted TF–TF partners 1 genes

MIG3

Explore 1 original interaction plots →