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AZF1

YOR113W

View at SGD ↗

Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Macisaac et. al
Fisher’s P-value4.84e-13
Information content14.77
Max PWM score16.21
Recommended cutoff13.05
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.014 0.332 0.001 0.001 0.027 0.180 0.014 0.111 0.069 0.069 0.001 0.152 0.235 0.250 0.014 0.001 0.055 0.042 
C | 0.216 0.064 0.001 0.001 0.015 0.549 0.007 0.015 0.098 0.181 0.416 0.764 0.015 0.001 0.299 0.125 0.007 0.540 
G | 0.007 0.022 0.042 0.001 0.223 0.049 0.216 0.181 0.015 0.015 0.001 0.015 0.181 0.500 0.007 0.292 0.216 0.001 
T | 0.763 0.582 0.956 0.997 0.735 0.222 0.763 0.693 0.818 0.735 0.582 0.069 0.569 0.250 0.680 0.582 0.722 0.417 
Position count matrix (PCM)
A |   1  33   0   0   2  18   1  11   6   6   0  15  23  25   1   0   5   4 
C |  21   6   0   0   1  54   0   1   9  18  41  76   1   0  29  12   0  54 
G |   0   2   4   0  22   4  21  18   1   1   0   1  18  50   0  29  21   0 
T |  76  58  95  99  73  22  76  69  81  73  58   6  56  25  68  58  72  41 
Position weight matrix (PWM)
A | -3.13  0.04 -5.77 -5.77 -2.47 -0.58 -3.13 -1.06 -1.53 -1.53 -5.77 -0.74 -0.31 -0.25 -3.13 -5.77 -1.76 -2.03 
C |  0.18 -1.03 -5.19 -5.19 -2.48  1.12 -3.25 -2.48 -0.61  0.01  0.84  1.45 -2.48 -5.19  0.51 -0.36 -3.25  1.10 
G | -3.25 -2.10 -1.46 -5.19  0.21 -1.30  0.18  0.01 -2.48 -2.48 -5.19 -2.48  0.01  1.02 -3.25  0.48  0.18 -5.19 
T |  0.87  0.60  1.09  1.14  0.83 -0.37  0.87  0.77  0.94  0.83  0.60 -1.53  0.58 -0.25  0.75  0.60  0.81  0.26 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 3

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

AZF1Badis et. al.P = 8.74e-05View matrix ↘
Sequence logo for AZF1
Fisher’s P-value8.74e-05
Information content9.194
Max PWM score8.87
Recommended cutoff8.87
Position frequency matrix (PFM)
A | 0.62 0.97 0.97 0.85 0.74 0.01 0.78 0.82 0.62 
C | 0.13 0.01 0.01 0.13 0.01 0.01 0.16 0.06 0.13 
G | 0.13 0.01 0.01 0.01 0.25 0.97 0.03 0.06 0.13 
T | 0.13 0.01 0.01 0.01 0.01 0.01 0.03 0.06 0.13 
Position count matrix (PCM)
A |  62  97  97  85  74   1  78  82  62 
C |  13   1   1  13   1   1  16   6  13 
G |  13   1   1   1  25  97   3   6  13 
T |  13   1   1   1   1   1   3   6  13 
Position weight matrix (PWM)
A |  0.66  1.11  1.11  0.98  0.84 -3.47  0.89  0.94  0.66 
C | -0.33 -2.89 -2.89 -0.33 -2.89 -2.89 -0.12 -1.10 -0.33 
G | -0.33 -2.89 -2.89 -2.89  0.33  1.68 -1.79 -1.10 -0.33 
T | -0.90 -3.47 -3.47 -3.47 -3.47 -3.47 -2.37 -1.67 -0.90 
AZF1Foat et. al.P = 5.88e-05View matrix ↘
Sequence logo for AZF1
Fisher’s P-value5.88e-05
Information content15.46
Max PWM score13.57
Recommended cutoff10.2
Position frequency matrix (PFM)
A | 0.01 0.01 0.01 0.88 0.92 0.81 0.79 0.03 0.01 0.01 0.55 0.97 
C | 0.01 0.01 0.94 0.01 0.06 0.01 0.16 0.49 0.19 0.01 0.01 0.01 
G | 0.97 0.97 0.01 0.01 0.01 0.17 0.01 0.31 0.01 0.01 0.04 0.01 
T | 0.01 0.01 0.04 0.11 0.01 0.01 0.04 0.17 0.79 0.97 0.41 0.01 
Position count matrix (PCM)
A |   1   1   1  88  92  81  79   3   1   1  55  97 
C |   1   1  94   1   6   1  16  49  19   1   1   1 
G |  97  97   1   1   1  17   1  31   1   1   4   1 
T |   1   1   4  11   1   1   4  17  79  97  41   1 
Position weight matrix (PWM)
A | -3.47 -3.47 -3.47  1.01  1.06  0.93  0.90 -2.37 -3.47 -3.47  0.54  1.11 
C | -2.89 -2.89  1.65 -2.89 -1.10 -2.89 -0.12  1.00  0.05 -2.89 -2.89 -2.89 
G |  1.68  1.68 -2.89 -2.89 -2.89 -0.06 -2.89  0.54 -2.89 -2.89 -1.50 -2.89 
T | -3.47 -3.47 -2.08 -1.07 -3.47 -3.47 -2.08 -0.63  0.90  1.11  0.25 -3.47 
AZF1Harbison et. al.P = 4.84e-13View matrix ↘
Sequence logo for AZF1
Fisher’s P-value4.84e-13
Information content14.79
Max PWM score16.21
Recommended cutoff13.05
Position frequency matrix (PFM)
A | 0.014 0.332 0.001 0.001 0.027 0.180 0.014 0.111 0.069 0.069 0.001 0.152 0.235 0.250 0.014 0.001 0.055 0.042 
C | 0.216 0.064 0.001 0.001 0.015 0.549 0.007 0.015 0.098 0.181 0.417 0.765 0.015 0.001 0.299 0.125 0.007 0.541 
G | 0.007 0.022 0.042 0.001 0.223 0.049 0.216 0.181 0.015 0.015 0.001 0.015 0.181 0.500 0.007 0.292 0.216 0.001 
T | 0.763 0.582 0.958 0.999 0.735 0.222 0.763 0.694 0.818 0.735 0.583 0.069 0.568 0.250 0.680 0.583 0.721 0.417 
Position count matrix (PCM)
A |   1  33   0   0   2  18   1  11   6   6   0  15  23  25   1   0   5   4 
C |  21   6   0   0   1  54   0   1   9  18  41  76   1   0  29  12   0  54 
G |   0   2   4   0  22   4  21  18   1   1   0   1  18  50   0  29  21   0 
T |  76  58  95  99  73  22  76  69  81  73  58   6  56  25  68  58  72  41 
Position weight matrix (PWM)
A | -3.13  0.04 -5.77 -5.77 -2.47 -0.58 -3.13 -1.06 -1.53 -1.53 -5.77 -0.74 -0.31 -0.25 -3.13 -5.77 -1.76 -2.03 
C |  0.18 -1.03 -5.19 -5.19 -2.48  1.12 -3.25 -2.48 -0.61  0.01  0.84  1.45 -2.48 -5.19  0.51 -0.36 -3.25  1.10 
G | -3.25 -2.10 -1.46 -5.19  0.21 -1.30  0.18  0.01 -2.48 -2.48 -5.19 -2.48  0.01  1.02 -3.25  0.48  0.18 -5.19 
T |  0.87  0.60  1.10  1.14  0.83 -0.37  0.87  0.77  0.94  0.83  0.60 -1.53  0.57 -0.25  0.75  0.60  0.81  0.26 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 97 genes

YAL032C, YAL037W, YAR009C, YAR019C, YAR023C, YBL029W, YBL074C, YBR157C, YBR158W, YBR159W, YBR230C, YBR281C, YBR282W, YDL037C, YDL122W, YDL245C, YDL246C, YDR001C, YDR002W, YDR006C, YDR007W, YDR042C, YDR257C, YDR259C, YDR441C, YDR442W, YDR524C, YDR525W, YDR526C, YEL047C, YEL050C, YEL055C, YEL062W, YEL063C, YER001W, YER007C-A, YER097W, YER098W, YER101C, YER102W, YFL034W, YGL001C, YGL012W, YGL013C, YGL115W, YGL135W, YGL136C, YGL189C, YGL195W, YGR001C, YGR084C, YGR085C, YGR190C, YHL034C, YHL041W, YIL014W, YIL015C-A, YIL056W, YIL099W, YIR020C, YJL048C, YJL148W, YJL191W, YJL192C, YJR100C, YJR158W, YLL019C, YLL020C, YLR023C, YLR027C, YLR074C, YLR075W, YLR166C, YLR167W, YLR367W, YLR368W, YLR413W, YML007W, YML008C, YML124C, YNL111C, YNL145W, YNR050C, YOL121C, YOR032C, YOR102W, YOR106W, YOR108W, YOR272W, YOR315W, YOR360C, YOR369C, YPL130W, YPL143W, YPR010C, YPR013C, YPR080W

Genes affected by TF deletion 18 genes

YPL016W, YML089C, YNL300W, YEL050C, YKL119C, YOL150C, YOR298W, YBL061C, YBR296C, YMR027W, YOR367W, YOL151W, YPL159C, YEL038W, YLR079W, YPR008W, YOR034C, YMR306W

Genes supported by both experiments 1 genes

YEL050C