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ARG81

YML099C, ARGRII, ARGR2

View at SGD ↗

Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Macisaac et. al
Fisher’s P-value1.50e-07
Information content10.82
Max PWM score9.69
Recommended cutoff5.2
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.300 0.040 0.080 0.970 0.010 0.010 0.010 0.320 
C | 0.060 0.010 0.010 0.010 0.970 0.010 0.970 0.320 
G | 0.420 0.020 0.900 0.010 0.010 0.010 0.010 0.020 
T | 0.220 0.930 0.010 0.010 0.010 0.970 0.010 0.340 
Position count matrix (PCM)
A |  30   4   8  97   1   1   1  32 
C |   6   1   1   1  97   1  97  32 
G |  42   2  90   1   1   1   1   2 
T |  22  93   1   1   1  97   1  34 
Position weight matrix (PWM)
A | -0.06 -2.08 -1.39  1.11 -3.47 -3.47 -3.47  0.00 
C | -1.10 -2.89 -2.89 -2.89  1.68 -2.89  1.68  0.58 
G |  0.85 -2.20  1.61 -2.89 -2.89 -2.89 -2.89 -2.20 
T | -0.37  1.07 -3.47 -3.47 -3.47  1.11 -3.47  0.06 
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 5

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

ARG81_AFoat et. al.P = 0.0001858View matrix ↘
Sequence logo for ARG81_A
Fisher’s P-value0.0001858
Information content18.57
Max PWM score20.5
Recommended cutoff10.7
Position frequency matrix (PFM)
A | 0.51 0.66 0.41 0.01 0.97 0.01 0.08 0.17 0.11 0.34 0.13 0.43 0.62 0.40 0.05 0.12 0.01 0.01 0.96 0.14 0.81 
C | 0.04 0.28 0.07 0.01 0.01 0.01 0.01 0.14 0.42 0.35 0.48 0.46 0.36 0.02 0.01 0.52 0.09 0.01 0.01 0.40 0.13 
G | 0.27 0.05 0.50 0.97 0.01 0.05 0.49 0.39 0.19 0.04 0.29 0.09 0.01 0.25 0.89 0.31 0.90 0.01 0.02 0.07 0.05 
T | 0.18 0.01 0.02 0.01 0.01 0.93 0.42 0.30 0.28 0.27 0.09 0.02 0.01 0.34 0.05 0.06 0.01 0.97 0.01 0.39 0.01 
Position count matrix (PCM)
A |  51  66  41   1  97   1   8  17  11  34  13  43  62  40   5  12   1   1  96  14  81 
C |   4  28   7   1   1   1   1  14  42  35  48  46  36   2   1  52   9   1   1  40  13 
G |  27   5  50  97   1   5  49  39  19   4  28   9   1  25  89  31  90   1   2   7   5 
T |  18   1   2   1   1  93  42  30  28  27   9   2   1  34   5   6   1  97   1  39   1 
Position weight matrix (PWM)
A |  0.47  0.72  0.25 -3.47  1.11 -3.47 -1.39 -0.63 -1.07  0.06 -0.90  0.30  0.66  0.22 -1.86 -0.98 -3.47 -3.47  1.10 -0.83  0.93 
C | -1.50  0.44 -0.94 -2.89 -2.89 -2.89 -2.89 -0.25  0.85  0.66  0.98  0.94  0.69 -2.20 -2.89  1.06 -0.69 -2.89 -2.89  0.80 -0.33 
G |  0.41 -1.28  1.02  1.68 -2.89 -1.28  1.00  0.77  0.05 -1.50  0.48 -0.69 -2.89  0.33  1.60  0.54  1.61 -2.89 -2.20 -0.94 -1.28 
T | -0.58 -3.47 -2.77 -3.47 -3.47  1.07  0.27 -0.06 -0.13 -0.17 -1.27 -2.77 -3.47  0.06 -1.86 -1.67 -3.47  1.11 -3.47  0.20 -3.47 
ARG81_BFoat et. al.P = 0.008544View matrix ↘
Sequence logo for ARG81_B
Fisher’s P-value0.008544
Information content13.38
Max PWM score13.06
Recommended cutoff10.32
Position frequency matrix (PFM)
A | 0.69 0.07 0.04 0.01 0.97 0.01 0.28 0.12 0.97 0.09 0.49 0.51 
C | 0.30 0.01 0.01 0.81 0.01 0.97 0.53 0.41 0.01 0.88 0.01 0.13 
G | 0.01 0.28 0.53 0.01 0.01 0.01 0.01 0.46 0.01 0.01 0.50 0.01 
T | 0.01 0.65 0.42 0.17 0.01 0.01 0.18 0.01 0.01 0.02 0.01 0.36 
Position count matrix (PCM)
A |  69   7   4   1  97   1  28  12  97   9  49  51 
C |  30   1   1  81   1  97  53  41   1  88   1  13 
G |   1  28  53   1   1   1   1  46   1   1  50   1 
T |   1  65  42  17   1   1  18   1   1   2   1  36 
Position weight matrix (PWM)
A |  0.77 -1.52 -2.08 -3.47  1.11 -3.47 -0.13 -0.98  1.11 -1.27  0.43  0.47 
C |  0.51 -2.89 -2.89  1.50 -2.89  1.68  1.08  0.82 -2.89  1.59 -2.89 -0.33 
G | -2.89  0.44  1.08 -2.89 -2.89 -2.89 -2.89  0.94 -2.89 -2.89  1.02 -2.89 
T | -3.47  0.71  0.27 -0.63 -3.47 -3.47 -0.58 -3.47 -3.47 -2.77 -3.47  0.12 
ARG81_AMorozov et. al.P = 0.0003338View matrix ↘
Sequence logo for ARG81_A
Fisher’s P-value0.0003338
Information content9.387
Max PWM score10.61
Recommended cutoff6.29
Position frequency matrix (PFM)
A | 0.095 0.013 0.025 0.059 0.609 0.081 0.038 0.063 0.019 
C | 0.856 0.095 0.175 0.270 0.167 0.034 0.754 0.121 0.129 
G | 0.034 0.870 0.761 0.023 0.149 0.314 0.153 0.690 0.679 
T | 0.015 0.022 0.039 0.648 0.075 0.571 0.055 0.127 0.172 
Position count matrix (PCM)
A |   9   1   2   5  60   8   3   6   1 
C |  85   9  17  27  16   3  75  12  12 
G |   3  87  76   2  14  31  15  69  67 
T |   1   2   3  64   7  57   5  12  17 
Position weight matrix (PWM)
A | -1.21 -3.20 -2.55 -1.69  0.64 -1.37 -2.13 -1.63 -2.82 
C |  1.56 -0.64 -0.03  0.41 -0.07 -1.67  1.43 -0.40 -0.33 
G | -1.67  1.58  1.44 -2.06 -0.19  0.56 -0.16  1.34  1.33 
T | -3.06 -2.68 -2.10  0.71 -1.45  0.58 -1.76 -0.92 -0.62 
ARG81_BMorozov et. al.P = 8.41e-05View matrix ↘
Sequence logo for ARG81_B
Fisher’s P-value8.41e-05
Information content8.075
Max PWM score12.57
Recommended cutoff8.26
Position frequency matrix (PFM)
A | 0.114 0.282 0.112 0.040 0.157 0.625 0.286 0.473 0.373 0.266 0.101 0.243 0.493 0.838 0.748 
C | 0.077 0.333 0.411 0.915 0.134 0.118 0.256 0.143 0.069 0.276 0.036 0.060 0.170 0.067 0.069 
G | 0.436 0.172 0.426 0.026 0.327 0.039 0.369 0.256 0.420 0.228 0.768 0.615 0.259 0.053 0.105 
T | 0.374 0.214 0.051 0.019 0.382 0.218 0.089 0.128 0.138 0.230 0.096 0.082 0.077 0.041 0.078 
Position count matrix (PCM)
A |  11  28  11   4  15  62  28  47  37  26  10  24  49  83  74 
C |   7  33  41  91  13  11  25  14   6  27   3   6  17   6   6 
G |  43  17  42   2  32   3  36  25  42  22  76  61  25   5  10 
T |  37  21   5   1  38  21   8  12  13  23   9   8   7   4   7 
Position weight matrix (PWM)
A | -1.03 -0.13 -1.05 -2.08 -0.71  0.67 -0.11  0.39  0.15 -0.18 -1.15 -0.28  0.43  0.96  0.85 
C | -0.85  0.62  0.83  1.63 -0.30 -0.42  0.35 -0.23 -0.96  0.43 -1.61 -1.10 -0.06 -0.99 -0.96 
G |  0.88 -0.05  0.86 -1.93  0.60 -1.53  0.72  0.35  0.85  0.24  1.45  1.23  0.36 -1.22 -0.54 
T |  0.16 -0.40 -1.84 -2.82  0.18 -0.38 -1.28 -0.92 -0.84 -0.33 -1.20 -1.36 -1.42 -2.05 -1.41 
ARG81_CMorozov et. al.P = 1.75e-06View matrix ↘
Sequence logo for ARG81_C
Fisher’s P-value1.75e-06
Information content7.701
Max PWM score8.67
Recommended cutoff6.26
Position frequency matrix (PFM)
A | 0.015 0.056 0.800 0.015 0.020 0.091 0.655 0.065 
C | 0.027 0.124 0.103 0.952 0.053 0.731 0.137 0.190 
G | 0.021 0.591 0.061 0.024 0.091 0.131 0.118 0.076 
T | 0.936 0.229 0.036 0.009 0.836 0.047 0.089 0.670 
Position count matrix (PCM)
A |   1   5  80   1   2   9  65   6 
C |   2  12  10  95   5  73  13  19 
G |   2  59   6   2   9  13  11   7 
T |  93  22   3   0  83   4   8  67 
Position weight matrix (PWM)
A | -3.06 -1.74  0.92 -3.06 -2.77 -1.26  0.72 -1.59 
C | -1.90 -0.37 -0.56  1.67 -1.22  1.40 -0.27  0.05 
G | -2.15  1.19 -1.08 -2.01 -0.68 -0.32 -0.42 -0.86 
T |  1.07 -0.33 -2.18 -3.57  0.96 -1.92 -1.28  0.74 
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 59 genes

YBR012W-A, YBR012W-B, YBR099C, YBR159W, YBR178W, YCR039C, YCR040W, YCR041W, YDL068W, YDL071C, YDL152W, YDR042C, YDR084C, YDR098C, YDR282C, YDR372C, YDR373W, YDR426C, YDR427W, YDR491C, YDR493W, YDR522C, YEL050C, YER007C-A, YER069W, YFL023W, YFL024C, YFL034W, YGL188C, YGR024C, YGR174C, YHR179W, YHR193C, YHR194W, YJL032W, YJL059W, YJL085W, YJL088W, YKL057C, YKL072W, YKR056W, YLR322W, YLR398C, YLR435W, YML098W, YML099C, YMR057C, YMR058W, YNL337W, YNR052C, YOL058W, YOL121C, YOL139C, YOL140W, YOR302W, YOR303W, YPL130W, YPL265W, YPL266W

Genes affected by TF deletion 118 genes

YLR276C, YOR191W, YPL211W, YPR080W, YDR187C, YGR153W, YOR003W, YFL013W-A, YOL140W, YPL283C, YPL111W, YGR296W, YGL244W, YKL088W, YJL088W, YKL087C, YLR438W, YLR411W, YPR119W, YDL039C, YDR472W, YDR504C, YGR038C-B, YMR141C, YNL123W, YNL187W, YOR325W, YCL028W, YDL164C, YDL228C, YGL145W, YGL117W, YML037C, YMR324C, YOR137C, YOR139C, YOR109W, YOR141C, YOR171C, YMR138W, YPL275W, YJL222W, YCR026C, YCR061W, YDR024W, YDR084C, YDR086C, YDR384C, YDR386W, YER129W, YER160C, YGL221C, YHL026C, YHR010W, YIL096C, YLR262C-A, YLR264W, YNL095C, YOL058W, YOL002C, YDL180W, YAR023C, YBR241C, YDR210W, YGL029W, YPR094W, YDR246W, YGL188C, YML097C, YDL115C, YNL161W, YNL193W, YOL154W, YOR302W, YGR230W, YLR142W, YDL047W, YDR515W, YLR014C, YMR118C, YOL119C, YOR303W, YER069W, YML099C, YML100W-A, YPL157W, YCR006C, YKR037C, YAL033W, YEL067C, YGR172C, YHR136C, YHR170W, YKL099C, YMR247C, YPR108W, YBL106C, YCR071C, YDR027C, YJR103W, YLR265C, YMR034C, YDR243C, YOR034C, YDL186W, YER076C, YLR148W, YFL068W, YKL038W, YLL057C, YMR157C, YCL010C, YIL071C, YIL010W, YKL224C, YKL162C, YML046W, YOR122C

Genes supported by both experiments 9 genes

YDR084C, YER069W, YGL188C, YJL088W, YML099C, YOL058W, YOL140W, YOR302W, YOR303W

Predicted TF–TF partners 2 genes

CAT8, STB4

Explore 2 original interaction plots →