S.ScerTFYeast transcription factor database Aaron Spivak
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ADR1

YDR216W

View at SGD ↗

Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization

01 / RECOMMENDED MATRIX

Best-performing DNA-binding model.

RecommendedSource: Foat et. al.
Fisher’s P-value6.00e-09
Information content13.55
Max PWM score14.38
Recommended cutoff10.8
View and copy the recommended matrices ↘
Position frequency matrix (PFM)
A | 0.58 0.06 0.05 0.01 0.52 0.86 0.30 0.01 0.01 0.02 0.02 0.03 0.51 
C | 0.31 0.01 0.11 0.88 0.01 0.01 0.59 0.97 0.21 0.16 0.01 0.57 0.34 
G | 0.02 0.15 0.80 0.03 0.43 0.07 0.10 0.01 0.01 0.77 0.08 0.09 0.01 
T | 0.10 0.78 0.04 0.09 0.04 0.07 0.02 0.01 0.78 0.06 0.89 0.30 0.15
Position count matrix (PCM)
A |  57   6   5   1  52  86  30   1   1   2   2   3  51 
C |  31   1  11  88   1   1  59  97  21  16   1  56  34 
G |   2  15  80   3  43   7  10   1   1  77   8   9   1 
T |  10  78   4   9   4   7   2   1  78   6  89  30  15
Position weight matrix (PWM)
A |  0.59 -1.67 -1.86 -3.47  0.49  0.99 -0.06 -3.47 -3.47 -2.77 -2.77 -2.37  0.47 
C |  0.54 -2.89 -0.49  1.59 -2.89 -2.89  1.19  1.68  0.15 -0.12 -2.89  1.15  0.64 
G | -2.20 -0.18  1.49 -1.79  0.87 -0.94 -0.59 -2.89 -2.89  1.45 -0.81 -0.69 -2.89 
T | -1.16  0.89 -2.08 -1.27 -2.08 -1.52 -2.77 -3.47  0.89 -1.67  1.02 -0.06 -0.76
02 / COMPARATIVE BENCHMARKS

Alternative candidate matrices 6

Historical matrix candidates from the original ScerTF database. Expand a source to inspect its original logo, scores, and matrix values.

ADR1Badis et. al.P = 0.02823View matrix ↘
Sequence logo for ADR1
Fisher’s P-value0.02823
Information content11.16
Max PWM score9.62
Recommended cutoff4.88
Position frequency matrix (PFM)
A | 0.73 0.01 0.01 0.01 0.01 0.70 0.24 
C | 0.06 0.97 0.97 0.97 0.97 0.01 0.66 
G | 0.06 0.01 0.01 0.01 0.01 0.28 0.05 
T | 0.15 0.01 0.01 0.01 0.01 0.01 0.05
Position count matrix (PCM)
A |  73   1   1   1   1  70  24 
C |   6  97  97  97  97   1  66 
G |   6   1   1   1   1  28   5 
T |  15   1   1   1   1   1   5
Position weight matrix (PWM)
A |  0.82 -3.47 -3.47 -3.47 -3.47  0.78 -0.29 
C | -1.10  1.68  1.68  1.68  1.68 -2.89  1.30 
G | -1.10 -2.89 -2.89 -2.89 -2.89  0.44 -1.28 
T | -0.76 -3.47 -3.47 -3.47 -3.47 -3.47 -1.86
Badis et. al.
ADR1_AFoat et. al.P = 1View matrix ↘
Sequence logo for ADR1_A
Fisher’s P-value1
Information content21.02
Max PWM score22.96
Recommended cutoff17.22
Position frequency matrix (PFM)
A | 0.08 0.24 0.18 0.01 0.01 0.01 0.09 0.01 0.10 0.04 0.43 0.23 0.17 0.14 0.03 0.13 0.41 0.71 0.01 0.87 0.97 0.63 0.56 
C | 0.74 0.32 0.31 0.01 0.97 0.01 0.06 0.41 0.35 0.10 0.48 0.50 0.13 0.83 0.20 0.01 0.21 0.01 0.09 0.01 0.01 0.36 0.21 
G | 0.07 0.40 0.32 0.97 0.01 0.01 0.85 0.30 0.20 0.23 0.06 0.01 0.39 0.01 0.67 0.46 0.01 0.03 0.01 0.10 0.01 0.01 0.22 
T | 0.10 0.03 0.19 0.01 0.01 0.97 0.01 0.29 0.35 0.63 0.03 0.26 0.31 0.02 0.10 0.41 0.38 0.26 0.90 0.02 0.01 0.01 0.01
Position count matrix (PCM)
A |   8  24  18   1   1   1   9   1  10   4  43  23  17  14   3  13  41  71   1  87  97  63  56 
C |  74  32  31   1  97   1   6  41  35  10  48  50  13  83  20   1  21   1   9   1   1  36  21 
G |   7  40  32  97   1   1  85  30  20  23   6   1  39   1  67  46   1   3   1  10   1   1  22 
T |  10   3  19   1   1  97   1  28  35  63   3  26  31   2  10  41  38  26  90   2   1   1   1
Position weight matrix (PWM)
A | -1.39 -0.29 -0.58 -3.47 -3.47 -3.47 -1.27 -3.47 -1.16 -2.08  0.30 -0.33 -0.63 -0.83 -2.37 -0.90  0.25  0.80 -3.47  1.00  1.11  0.68  0.56 
C |  1.41  0.58  0.54 -2.89  1.68 -2.89 -1.10  0.82  0.66 -0.59  0.98  1.02 -0.33  1.53  0.11 -2.89  0.15 -2.89 -0.69 -2.89 -2.89  0.69  0.15 
G | -0.94  0.80  0.58  1.68 -2.89 -2.89  1.55  0.51  0.11  0.25 -1.10 -2.89  0.77 -2.89  1.31  0.94 -2.89 -1.79 -2.89 -0.59 -2.89 -2.89  0.20 
T | -1.16 -2.37 -0.52 -3.47 -3.47  1.11 -3.47 -0.10  0.09  0.68 -2.37 -0.21 -0.03 -2.77 -1.16  0.25  0.17 -0.21  1.03 -2.77 -3.47 -3.47 -3.47
Foat et. al.
ADR1_BFoat et. al.P = 0.04009View matrix ↘
Sequence logo for ADR1_B
Fisher’s P-value0.04009
Information content10.51
Max PWM score11.95
Recommended cutoff10.38
Position frequency matrix (PFM)
A | 0.12 0.29 0.18 0.73 0.60 0.01 0.18 0.11 0.03 0.46 0.01 0.46 0.39 0.33 
C | 0.59 0.03 0.27 0.01 0.19 0.96 0.17 0.38 0.01 0.01 0.02 0.12 0.01 0.08 
G | 0.28 0.24 0.46 0.01 0.21 0.02 0.29 0.08 0.01 0.01 0.96 0.42 0.35 0.13 
T | 0.01 0.44 0.08 0.25 0.01 0.01 0.35 0.42 0.95 0.53 0.01 0.01 0.26 0.47
Position count matrix (PCM)
A |  12  28  18  73  60   1  18  11   3  46   1  46  39  33 
C |  59   3  27   1  19  96  17  38   1   1   2  12   1   8 
G |  28  24  46   1  21   2  28   8   1   1  96  42  35  13 
T |   1  44   8  25   1   1  35  42  95  53   1   1  26  47
Position weight matrix (PWM)
A | -0.98 -0.10 -0.58  0.82  0.63 -3.47 -0.58 -1.07 -2.37  0.36 -3.47  0.36  0.20  0.03 
C |  1.19 -1.79  0.41 -2.89  0.05  1.67 -0.06  0.75 -2.89 -2.89 -2.20 -0.41 -2.89 -0.81 
G |  0.44  0.29  0.94 -2.89  0.15 -2.20  0.48 -0.81 -2.89 -2.89  1.67  0.85  0.66 -0.33 
T | -3.47  0.32 -1.39 -0.25 -3.47 -3.47  0.09  0.27  1.09  0.50 -3.47 -3.47 -0.21  0.38
Foat et. al.
ADR1Harbison et. al.P = 0.04369View matrix ↘
Sequence logo for ADR1
Fisher’s P-value0.04369
Information content8.37
Max PWM score7.37
Recommended cutoff5.63
Position frequency matrix (PFM)
A | 0.250 0.012 0.012 0.488 0.012 0.012 
C | 0.250 0.012 0.012 0.012 0.012 0.012 
G | 0.250 0.964 0.964 0.488 0.964 0.488 
T | 0.250 0.012 0.012 0.012 0.012 0.488
Position count matrix (PCM)
A |  25   1   1  48   1   1 
C |  25   1   1   1   1   1 
G |  25  96  96  48  96  48 
T |  25   1   1   1   1  48
Position weight matrix (PWM)
A | -0.25 -3.28 -3.28  0.42 -3.28 -3.28 
C |  0.33 -2.71 -2.71 -2.71 -2.71 -2.71 
G |  0.33  1.68  1.68  1.00  1.68  1.00 
T | -0.25 -3.28 -3.28 -3.28 -3.28  0.42
Harbison et. al.
ADR1Macisaac et. alP = 0.04369View matrix ↘
Sequence logo for ADR1
Fisher’s P-value0.04369
Information content8.37
Max PWM score7.37
Recommended cutoff5.63
Position frequency matrix (PFM)
A | 0.250 0.012 0.012 0.488 0.012 0.012 
C | 0.250 0.012 0.012 0.012 0.012 0.012 
G | 0.250 0.964 0.964 0.488 0.964 0.488 
T | 0.250 0.012 0.012 0.012 0.012 0.488
Position count matrix (PCM)
A |  25   1   1  48   1   1 
C |  25   1   1   1   1   1 
G |  25  96  96  48  96  48 
T |  25   1   1   1   1  48
Position weight matrix (PWM)
A | -0.25 -3.28 -3.28  0.42 -3.28 -3.28 
C |  0.33 -2.71 -2.71 -2.71 -2.71 -2.71 
G |  0.33  1.68  1.68  1.00  1.68  1.00 
T | -0.25 -3.28 -3.28 -3.28 -3.28  0.42
Macisaac et. al
ADR1Pachkov et alP = 0.09011View matrix ↘
Sequence logo for ADR1
Fisher’s P-value0.09011
Information content11.21
Max PWM score9.12
Recommended cutoff5.55
Position frequency matrix (PFM)
A | 0.001 0.001 0.001 0.001 0.884 1.000 0.001 
C | 1.000 0.239 0.934 0.823 0.116 0.001 0.601 
G | 0.001 0.001 0.066 0.001 0.001 0.001 0.001 
T | 0.001 0.761 0.001 0.177 0.001 0.001 0.399
Position count matrix (PCM)
A |   0   0   0   0  88 100   0 
C | 100  23  93  82  11   0  60 
G |   0   0   6   0   0   0   0 
T |   0  76   0  17   0   0  39
Position weight matrix (PWM)
A | -5.77 -5.77 -5.77 -5.77  1.02  1.14 -5.77 
C |  1.71  0.28  1.65  1.52 -0.44 -5.19  1.21 
G | -5.19 -5.19 -1.00 -5.19 -5.19 -5.19 -5.19 
T | -5.77  0.87 -5.77 -0.59 -5.77 -5.77  0.22
Pachkov et al
03 / EXPERIMENTAL CONTEXT

Gene-level annotations and interactions.

Genes bound in ChIP-chip experiments 146 genes

YAL022C, YAR009C, YBL025W, YBR109C, YBR110W, YBR163W, YBR223C, YBR226C, YBR227C, YBR228W, YBR236C, YBR237W, YBR256C, YBR257W, YBR298C, YBR299W, YCL051W, YCL052C, YCL055W, YCL056C, YCR054C, YCR095C, YDL017W, YDL018C, YDL027C, YDL054C, YDL073W, YDL074C, YDL089W, YDL090C, YDL117W, YDL119C, YDL122W, YDL159W, YDL160C, YDL176W, YDL177C, YDL179W, YDL240W, YDR045C, YDR159W, YDR164C, YDR165W, YDR183W, YDR236C, YDR237W, YDR279W, YDR289C, YDR318W, YEL004W, YEL005C, YEL061C, YER057C, YER058W, YER099C, YER100W, YER133W, YFL012W, YFL013C, YFR007W, YFR023W, YFR044C, YFR045W, YGL083W, YGL084C, YGL133W, YGL139W, YGL140C, YGL204C, YGL258W, YGR098C, YGR099W, YGR191W, YGR223C, YGR224W, YHR008C, YHR044C, YHR045W, YHR056C, YHR101C, YHR102W, YIL003W, YIL004C, YIL016W, YIL146C, YJL023C, YJL146W, YJL147C, YJL155C, YJL205C-A, YJR004C, YJR005W, YJR088C, YJR089W, YJR154W, YKL015W, YKL016C, YKL071W, YKL216W, YKR051W, YLL016W, YLL035W, YLL036C, YLL038C, YLR035C-A, YLR222C, YLR329W, YLR365W, YLR366W, YLR455W, YML001W, YML108W, YMR158W-A, YMR169C, YNL100W, YNL126W, YNL264C, YNR006W, YNR011C, YNR012W, YNR054C, YNR059W, YOL164W, YOR018W, YOR056C, YOR057W, YOR114W, YOR115C, YOR387C, YPL006W, YPL007C, YPL010W, YPL011C, YPL022W, YPL023C, YPL114W, YPL115C, YPL147W, YPL148C, YPL173W, YPL174C, YPL235W, YPL236C, YPL254W, YPR071W, YPR121W

Genes affected by TF deletion 30 genes

YJR048W, YOR377W, YPL016W, YBR129C, YDR099W, YDR530C, YOL107W, YCL012W, YCR050C, YAR003W, YLR439W, YOR043W, YER152C, YNR066C, YJR148W, YLR099C, YBR132C, YMR291W, YPL156C, YNL154C, YJL152W, YGR294W, YPL066W, YKL030W, YIL062C, YJL206C, YHR136C, YFR055W, YHR135C, YHR137W